What is acamprosate? Acamprosate is used to help maintain sobriety in alcohol-dependent adults who no longer drink alcohol. acamprosate is used with behavioral therapy or counseling support to help prevent an urge to drink again. Acamprosate will not treat or prevent alcohol withdrawal symptoms. Acamprosate may not be as effective if you have not gone through detox and stopped drinking alcohol completely. This medicine is also unlikely to be effective in people who abuse drugs or other substances. Acamprosate may also be used for purposes not listed in this medication guide. Warnings Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies. Before taking this medicine You should not use acamprosate if you are allergic to it, or if you have severe kidney disease. Tell your doctor if you have ever had kidney problems. Some people have thoughts about suicide while taking acamprosate. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Tell your doctor if you are pregnant or breastfeeding. How should I take acamprosate? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Start taking acamprosate as soon as possible after you have quit drinking. May be taken with or without food. If you routinely eat 3 meals daily, take the medicine at each meal. Swallow the tablet whole and do not crush, chew, or break it. Keep taking acamprosate as directed even if you relapse and drink alcohol. Tell your doctor about any alcohol you consume, no matter how much. Your treatment will also include counseling support and continued abstinence from alcohol. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking acamprosate? Follow your doctor's instructions about any restrictions on food, beverages, or activity. Acamprosate side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: severe anxiety or depression; mood or behavior changes; thoughts about suicide or hurting yourself; severe diarrhea; or kidney problems--swelling, urinating less, feeling tired or short of breath. Common side effects may include: anxiety, depressed mood; dizziness; sleep problems; pain, weakness; itching, sweating, tingling; nausea, diarrhea, gas, loss of appetite; or dry mouth. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Acamprosate dosing information Usual Adult Dose for Alcohol Dependence: 666 mg orally 3 times a day Comments: -Doses should be taken with meals in patients who regularly eat 3 meals a day. -Treatment should begin as soon as possible after the withdrawal period (when the patient achieves abstinence) and should be maintained if the patient relapses. -This drug should be used as part of a comprehensive psychosocial treatment program. -Lower doses may be effective in some patients. Use: For the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation What other drugs will affect acamprosate? Other drugs may affect acamprosate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

What is acyclovir? Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus in the body. It will not cure herpes, but it can lessen the symptoms of the infection. Acyclovir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chickenpox. Sitavig (acyclovir tablet, delayed release) is only for use in treating cold sores on the lips. Sitavig will not treat genital herpes. Warnings Take acyclovir for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Treatment with acyclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others. Before taking this medicine You should not take this medicine if you are allergic to acyclovir or valacyclovir (Valtrex). You should not take acyclovir buccal tablets (Sitavig) if you are allergic to milk proteins. To make sure this medicine is safe for you, tell your doctor if you have: kidney disease; or a weak immune system (caused by disease or by using certain medicine). Tell your doctor if you are pregnant or breastfeeding. Herpes can be passed to your baby during childbirth if you have a genital lesion when your baby is born. If you have genital herpes, it is very important to prevent herpes lesions during pregnancy. Take your medicine as directed to best control your infection. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Acyclovir should not be given to a child younger than 2 years old. How should I take acyclovir? Take acyclovir exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Start taking acyclovir as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). Start taking Sitavig within 1 hour after you first notice sold core symptoms, before the cold sore appears. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Do not crush, chew, suck on, or swallow a buccal tablet. Place the flat side of the tablet against your upper gum, on the same side of the mouth as your cold sore. Allow the tablet to dissolve in your mouth throughout the day. You may eat and drink normally while the buccal tablet is in place. Do not give an acyclovir buccal tablet to a young child or choking could occur. Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Acyclovir doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight. Drink plenty of water while you are taking this medicine to keep your kidneys working properly. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses may increase the risk of your virus becoming resistant to medication. Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What to avoid Avoid brushing your teeth, chewing gum, or wearing an upper denture while you have a buccal tablet in your mouth. You may rinse your mouth gently. Drink plenty of liquids to prevent dry mouth. Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others. Taking acyclovir will not prevent you from passing genital herpes to your sexual partner. Avoid sexual intercourse while you have active lesions or the first symptoms of an outbreak. Genital herpes may still be contagious through "viral shedding" from your skin, even if you have no symptoms. Acyclovir side effects Get emergency medical help if you have signs of an allergic reaction to acyclovir: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: easy bruising or bleeding, purple or red pinpoint spots under your skin; changes in behavior; confusion, hallucinations; or signs of a kidney problem - little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath. Common acyclovir side effects may include: mild skin pain; rash, itching; nausea, vomiting, diarrhea; headache; or mouth pain while using an acyclovir buccal tablet. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Acyclovir side effects What other drugs will affect acyclovir? Acyclovir can harm your kidneys, especially if you also use certain medicines for infections, cancer, osteoporosis, organ transplant rejection, bowel disorders, high blood pressure, or pain or arthritis (including Advil, Motrin, and Aleve). Other drugs may interact with acyclovir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.  

What is acyclovir? Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus in the body. It will not cure herpes, but it can lessen the symptoms of the infection. Acyclovir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chickenpox. Sitavig (acyclovir tablet, delayed release) is only for use in treating cold sores on the lips. Sitavig will not treat genital herpes.   Warnings Take acyclovir for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Treatment with acyclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.   Before taking this medicine You should not take this medicine if you are allergic to acyclovir or valacyclovir (Valtrex). You should not take acyclovir buccal tablets (Sitavig) if you are allergic to milk proteins. To make sure this medicine is safe for you, tell your doctor if you have: kidney disease; or a weak immune system (caused by disease or by using certain medicine). Tell your doctor if you are pregnant or breastfeeding. Herpes can be passed to your baby during childbirth if you have a genital lesion when your baby is born. If you have genital herpes, it is very important to prevent herpes lesions during pregnancy. Take your medicine as directed to best control your infection. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Acyclovir should not be given to a child younger than 2 years old.   How should I take acyclovir? Take acyclovir exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Start taking acyclovir as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). Start taking Sitavig within 1 hour after you first notice sold core symptoms, before the cold sore appears. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Do not crush, chew, suck on, or swallow a buccal tablet. Place the flat side of the tablet against your upper gum, on the same side of the mouth as your cold sore. Allow the tablet to dissolve in your mouth throughout the day. You may eat and drink normally while the buccal tablet is in place. Do not give an acyclovir buccal tablet to a young child or choking could occur. Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Acyclovir doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight. Drink plenty of water while you are taking this medicine to keep your kidneys working properly. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses may increase the risk of your virus becoming resistant to medication. Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions. Store at room temperature away from moisture and heat.   Detailed Acyclovir dosage information What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What to avoid Avoid brushing your teeth, chewing gum, or wearing an upper denture while you have a buccal tablet in your mouth. You may rinse your mouth gently. Drink plenty of liquids to prevent dry mouth. Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others. Taking acyclovir will not prevent you from passing genital herpes to your sexual partner. Avoid sexual intercourse while you have active lesions or the first symptoms of an outbreak. Genital herpes may still be contagious through "viral shedding" from your skin, even if you have no symptoms.   Acyclovir side effects Get emergency medical help if you have signs of an allergic reaction to acyclovir: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: easy bruising or bleeding, purple or red pinpoint spots under your skin; changes in behavior; confusion, hallucinations; or signs of a kidney problem - little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath. Common acyclovir side effects may include: mild skin pain; rash, itching; nausea, vomiting, diarrhea; headache; or mouth pain while using an acyclovir buccal tablet. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect acyclovir? Acyclovir can harm your kidneys, especially if you also use certain medicines for infections, cancer, osteoporosis, organ transplant rejection, bowel disorders, high blood pressure, or pain or arthritis (including Advil, Motrin, and Aleve). Other drugs may interact with acyclovir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is acyclovir? Acyclovir is an antiviral drug. It slows the growth and spread of the herpes virus in the body. It will not cure herpes, but it can lessen the symptoms of the infection. Acyclovir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chickenpox. Sitavig (acyclovir tablet, delayed release) is only for use in treating cold sores on the lips. Sitavig will not treat genital herpes.   Warnings Take acyclovir for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Treatment with acyclovir should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.   Before taking this medicine You should not take this medicine if you are allergic to acyclovir or valacyclovir (Valtrex). You should not take acyclovir buccal tablets (Sitavig) if you are allergic to milk proteins. To make sure this medicine is safe for you, tell your doctor if you have: kidney disease; or a weak immune system (caused by disease or by using certain medicine). Tell your doctor if you are pregnant or breastfeeding. Herpes can be passed to your baby during childbirth if you have a genital lesion when your baby is born. If you have genital herpes, it is very important to prevent herpes lesions during pregnancy. Take your medicine as directed to best control your infection. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Acyclovir should not be given to a child younger than 2 years old.   How should I take acyclovir? Take acyclovir exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Start taking acyclovir as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). Start taking Sitavig within 1 hour after you first notice sold core symptoms, before the cold sore appears. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Do not crush, chew, suck on, or swallow a buccal tablet. Place the flat side of the tablet against your upper gum, on the same side of the mouth as your cold sore. Allow the tablet to dissolve in your mouth throughout the day. You may eat and drink normally while the buccal tablet is in place. Do not give an acyclovir buccal tablet to a young child or choking could occur. Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Acyclovir doses are based on weight (especially in children and teenagers). Your dose needs may change if you gain or lose weight. Drink plenty of water while you are taking this medicine to keep your kidneys working properly. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses may increase the risk of your virus becoming resistant to medication. Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions. Store at room temperature away from moisture and heat.   Detailed Acyclovir dosage information What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What to avoid Avoid brushing your teeth, chewing gum, or wearing an upper denture while you have a buccal tablet in your mouth. You may rinse your mouth gently. Drink plenty of liquids to prevent dry mouth. Herpes infections are contagious and you can infect other people, even while you are being treated with acyclovir. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others. Taking acyclovir will not prevent you from passing genital herpes to your sexual partner. Avoid sexual intercourse while you have active lesions or the first symptoms of an outbreak. Genital herpes may still be contagious through "viral shedding" from your skin, even if you have no symptoms.   Acyclovir side effects Get emergency medical help if you have signs of an allergic reaction to acyclovir: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: easy bruising or bleeding, purple or red pinpoint spots under your skin; changes in behavior; confusion, hallucinations; or signs of a kidney problem - little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath. Common acyclovir side effects may include: mild skin pain; rash, itching; nausea, vomiting, diarrhea; headache; or mouth pain while using an acyclovir buccal tablet. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect acyclovir? Acyclovir can harm your kidneys, especially if you also use certain medicines for infections, cancer, osteoporosis, organ transplant rejection, bowel disorders, high blood pressure, or pain or arthritis (including Advil, Motrin, and Aleve). Other drugs may interact with acyclovir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is albuterol inhalation? Albuterol is a bronchodilator that relaxes muscles in the airways and increases air flow to the lungs. Albuterol inhalation is used to treat or prevent bronchospasm, or narrowing of the airways in the lungs, in people with asthma or certain types of chronic obstructive pulmonary disease (COPD). It is also used to prevent exercise-induced bronchospasm. Albuterol inhalation is for use in adults and children who are at least 4 years old. Always follow your doctor's directions when giving albuterol to a child. Warnings It is important to keep albuterol on hand at all times. Get your prescription refilled before you run out of medicine completely. Keep using all of your other medications as prescribed by your doctor. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing attacks. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor. An increased need for medication could be an early sign of a serious asthma attack. Only use albuterol as prescribed by your physician. An overdose of albuterol can be fatal. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of albuterol can be fatal. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Before taking this medicine You should not use this medicine if you are allergic to albuterol. You should not use ProAir RespiClick if you are allergic to milk proteins. Albuterol may increase the risk of death or hospitalization in people with asthma, but the risk in people with obstructive airway disease or chronic obstructive pulmonary disease (COPD) is not known. To make sure albuterol inhalation is safe for you, tell your doctor if you have: heart disease, high blood pressure, congestive heart failure; a heart rhythm disorder; a seizure disorder such as epilepsy; diabetes; overactive thyroid; or low levels of potassium in your blood. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether albuterol will harm an unborn baby. However, having uncontrolled asthma during pregnancy may increase the risk of premature birth, low birth weight, or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of preventing bronchospasm may outweigh any risks to the baby. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of albuterol on the baby. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. How should I use albuterol inhalation? Use albuterol inhalation exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use albuterol inhalation in larger or smaller amounts or for longer than recommended. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. You may need to prime your albuterol inhaler device before the first use. Your medicine comes with directions for priming if needed. You may also need to shake your albuterol device just before each use. Keeping your inhaler clean is important to ensure you are receiving the medication. Clean the plastic actuator with the canister removed at least once a week. Your medicine comes with directions for properly cleaning your device. Follow all medication instructions very carefully. Do not allow a young child to use albuterol inhalation without help from an adult. The usual dose of albuterol inhalation is 2 inhalations every 4 to 6 hours. To prevent exercise-induced bronchospasm, use 2 inhalations 15 to 30 minutes before you exercise. The effects of albuterol inhalation should last about 4 to 6 hours. Seek medical attention if you think your asthma medications are not working as well. An increased need for medication could be an early sign of a serious asthma attack. Use the dose counter on your albuterol inhaler device and get your prescription refilled before you run out of medicine completely. Always use the new inhaler device provided with your refill. Do not float a medicine canister in water to see if it is empty. ProAir HFA, Proventil HFA, or Ventolin HFA must be shaken before each use. You do not need to shake ProAir RespiClick before using. Follow all product instructions on how to clean your albuterol inhaler device and mouthpiece. Do not try to clean or take apart the ProAir RespiClick inhaler device. Asthma is often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Store at room temperature away from moisture, heat, or cold temperatures. Keep the albuterol canister away from open flame or high heat, such as in a car on a hot day. The canister may explode if it gets too hot. Do not puncture or burn an empty inhaler canister.   What happens if I miss a dose? Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of albuterol can be fatal. Overdose symptoms may include dry mouth, tremors, chest pain, fast or irregular heartbeat, nausea, general ill feeling, seizure (convulsions), feeling light-headed or fainting. What should I avoid while using albuterol inhalation? Rinse with water if this medicine gets in your eyes. Albuterol inhalation side effects Get emergency medical help if you have signs of an allergic reaction to albuterol: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: wheezing, choking, or other breathing problems after using this medicine; chest pain, fast heart rate, pounding heartbeats or fluttering in your chest; pain or burning when you urinate; increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss; or signs of low potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, extreme thirst, increased urination, numbness or tingling, muscle weakness or limp feeling. Common albuterol side effects may include: chest pain, fast or pounding heartbeats; upset stomach, vomiting; painful urination; dizziness; feeling shaky or nervous; headache, back pain, body aches; or cough, sore throat, sinus pain, runny or stuffy nose. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect albuterol inhalation? Tell your doctor about all your current medicines and any you start or stop using, especially: any other inhaled medicines or bronchodilators; digoxin; a diuretic or "water pill"; an antidepressant - amitriptyline, desipramine, imipramine, doxepin, nortriptyline, and others; a beta blocker - atenolol, carvedilol, labetalol, metoprolol, propranolol, sotalol, and others; or a MAO inhibitor - isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine, and others or methylene blue injection This list is not complete. Other drugs may interact with albuterol inhalation, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What is albuterol inhalation? Albuterol is a bronchodilator that relaxes muscles in the airways and increases air flow to the lungs. Albuterol inhalation is used to treat or prevent bronchospasm, or narrowing of the airways in the lungs, in people with asthma or certain types of chronic obstructive pulmonary disease (COPD). It is also used to prevent exercise-induced bronchospasm. Albuterol inhalation is for use in adults and children who are at least 4 years old. Always follow your doctor's directions when giving albuterol to a child. Warnings It is important to keep albuterol on hand at all times. Get your prescription refilled before you run out of medicine completely. Keep using all of your other medications as prescribed by your doctor. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing attacks. If it seems like you need to use more of any of your medications in a 24-hour period, talk with your doctor. An increased need for medication could be an early sign of a serious asthma attack. Only use albuterol as prescribed by your physician. An overdose of albuterol can be fatal. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of albuterol can be fatal. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Before taking this medicine You should not use this medicine if you are allergic to albuterol. You should not use ProAir RespiClick if you are allergic to milk proteins. Albuterol may increase the risk of death or hospitalization in people with asthma, but the risk in people with obstructive airway disease or chronic obstructive pulmonary disease (COPD) is not known. To make sure albuterol inhalation is safe for you, tell your doctor if you have: heart disease, high blood pressure, congestive heart failure; a heart rhythm disorder; a seizure disorder such as epilepsy; diabetes; overactive thyroid; or low levels of potassium in your blood. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether albuterol will harm an unborn baby. However, having uncontrolled asthma during pregnancy may increase the risk of premature birth, low birth weight, or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of preventing bronchospasm may outweigh any risks to the baby. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of albuterol on the baby. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. How should I use albuterol inhalation? Use albuterol inhalation exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use albuterol inhalation in larger or smaller amounts or for longer than recommended. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. You may need to prime your albuterol inhaler device before the first use. Your medicine comes with directions for priming if needed. You may also need to shake your albuterol device just before each use. Keeping your inhaler clean is important to ensure you are receiving the medication. Clean the plastic actuator with the canister removed at least once a week. Your medicine comes with directions for properly cleaning your device. Follow all medication instructions very carefully. Do not allow a young child to use albuterol inhalation without help from an adult. The usual dose of albuterol inhalation is 2 inhalations every 4 to 6 hours. To prevent exercise-induced bronchospasm, use 2 inhalations 15 to 30 minutes before you exercise. The effects of albuterol inhalation should last about 4 to 6 hours. Seek medical attention if you think your asthma medications are not working as well. An increased need for medication could be an early sign of a serious asthma attack. Use the dose counter on your albuterol inhaler device and get your prescription refilled before you run out of medicine completely. Always use the new inhaler device provided with your refill. Do not float a medicine canister in water to see if it is empty. ProAir HFA, Proventil HFA, or Ventolin HFA must be shaken before each use. You do not need to shake ProAir RespiClick before using. Follow all product instructions on how to clean your albuterol inhaler device and mouthpiece. Do not try to clean or take apart the ProAir RespiClick inhaler device. Asthma is often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Store at room temperature away from moisture, heat, or cold temperatures. Keep the albuterol canister away from open flame or high heat, such as in a car on a hot day. The canister may explode if it gets too hot. Do not puncture or burn an empty inhaler canister.   What happens if I miss a dose? Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of albuterol can be fatal. Overdose symptoms may include dry mouth, tremors, chest pain, fast or irregular heartbeat, nausea, general ill feeling, seizure (convulsions), feeling light-headed or fainting. What should I avoid while using albuterol inhalation? Rinse with water if this medicine gets in your eyes. Albuterol inhalation side effects Get emergency medical help if you have signs of an allergic reaction to albuterol: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: wheezing, choking, or other breathing problems after using this medicine; chest pain, fast heart rate, pounding heartbeats or fluttering in your chest; pain or burning when you urinate; increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss; or signs of low potassium - leg cramps, constipation, irregular heartbeats, fluttering in your chest, extreme thirst, increased urination, numbness or tingling, muscle weakness or limp feeling. Common albuterol side effects may include: chest pain, fast or pounding heartbeats; upset stomach, vomiting; painful urination; dizziness; feeling shaky or nervous; headache, back pain, body aches; or cough, sore throat, sinus pain, runny or stuffy nose. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect albuterol inhalation? Tell your doctor about all your current medicines and any you start or stop using, especially: any other inhaled medicines or bronchodilators; digoxin; a diuretic or "water pill"; an antidepressant - amitriptyline, desipramine, imipramine, doxepin, nortriptyline, and others; a beta blocker - atenolol, carvedilol, labetalol, metoprolol, propranolol, sotalol, and others; or a MAO inhibitor - isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine, and others or methylene blue injection This list is not complete. Other drugs may interact with albuterol inhalation, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What is alclometasone topical? Alclometasone is a topical steroid. It reduces the actions of chemicals in the body that cause inflammation. Alclometasone topical (for the skin) is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. Alclometasone topical may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Before taking this medicine You should not use alclometasone topical if you are allergic to it. Do not use alclometasone topical to treat diaper rash. To make sure alclometasone topical is safe for you, tell your doctor if you have: bacterial, fungal, or viral skin infection. Steroids can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes. FDA pregnancy category C. It is not known whether alclometasone topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using alclometasone topical. It is not known whether alclometasone topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Alclometasone topical should not be used on a child younger than 1 year old. Do not use this medicine on any child without a doctor's advice. Children can absorb larger amounts of this medication through the skin and may be more likely to have side effects. How should I use alclometasone topical? Alclometasone topical is usually applied 2 or 3 times per day. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Wash your hands before and after using alclometasone topical, unless you are using the medicine to treat the skin on your hands. Apply a small amount to the affected area and rub it gently into the skin. Do not apply alclometasone topical over a large area of skin. Do not cover the treated skin area unless your doctor tells you to. Call your doctor if your symptoms do not improve after 2 weeks of treatment, or if they get worse while using alclometasone topical. Store at room temperature away from moisture and heat. What happens if I miss a dose? Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. An overdose of alclometasone topical is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid while using alclometasone topical? Avoid getting alclometasone topical in your eyes. If contact does occur, rinse with water. Do not use alclometasone topical on broken or infected skin. Also avoid using this medicine in open wounds. Avoid applying alclometasone topical to the skin of your face, underarms, or groin area without your doctor's instruction. Do not use alclometasone topical to treat any condition that has not been checked by your doctor. Alclometasone topical side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body. Stop using alclometasone topical and call your doctor if you have: blurred vision, or seeing halos around lights; uneven heartbeats; sleep problems (insomnia); weight gain, puffiness in your face; or tired feeling. Common side effects may include: redness, burning, or itching of treated skin; skin dryness or irritation; acne, skin rash; lightened color of treated skin; or folliculitis (redness or crusting around your hair follicles). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Alclometasone topical dosing information Usual Adult Dose for Dermatitis: Apply a thin film to the affected area two or three times a day Comments: Massage gently until the drug disappears Use: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses Usual Adult Dose for Eczema: Apply a thin film to the affected area two or three times a day Comments: Massage gently until the drug disappears Use: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses Usual Pediatric Dose for Dermatitis: 1 year or older: Apply a thin film to the affected area two or three times a day Comments: -Massage gently until the drug disappears -Safety and efficacy of drug use in pediatric patients for longer than 3 weeks have not been established. Use: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses Usual Pediatric Dose for Eczema: 1 year or older: Apply a thin film to the affected area two or three times a day Comments: -Massage gently until the drug disappears -Safety and efficacy of drug use in pediatric patients for longer than 3 weeks have not been established. Use: Relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses   What other drugs will affect alclometasone topical? It is not likely that other drugs you take orally or inject will have an effect on topically applied alclometasone. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

What is alendronate? Alendronate is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. alendronate is for use when you have a high risk of bone fracture due to osteoporosis. Alendronate is also used to treat Paget's disease of bone. Alendronate may also be used for purposes not listed in this medication guide. Warnings You should not take alendronate if you have problems with your esophagus, or low levels of calcium in your blood. Do not take alendronate if you cannot sit upright or stand for at least 30 minutes after taking the medicine. Alendronate can cause serious problems in the stomach or esophagus. Stop using alendronate and call your doctor at once if you have chest pain, new or worsening heartburn, or pain when swallowing. Also call your doctor if you have muscle spasms, numbness or tingling (in hands and feet or around the mouth), new or unusual hip pain, or severe pain in your joints, bones, or muscles. Before taking this medicine You should not take alendronate if you are allergic to it, or if you have: low levels of calcium in your blood (hypocalcemia); or problems with the muscles in your esophagus (the tube that connects your mouth and stomach). Do not take alendronate if you cannot sit upright or stand for at least 30 minutes. Alendronate can cause serious problems in the stomach or esophagus. You must stay upright for at least 30 minutes after taking alendronate. Tell your doctor if you have ever had: trouble swallowing; problems with your stomach or digestion; hypocalcemia; a dental problem (you may need a dental exam before you begin taking alendronate); kidney disease; or any condition that makes it hard for your body to absorb nutrients from food (malabsorption). The effervescent tablet contains a lot of sodium. Tell your doctor if you are on a low-salt diet before using this form of alendronate. This medicine may cause jaw bone problems (osteonecrosis). The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. Ask your doctor about your own risk. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or trying to become pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. How should I take alendronate? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Alendronate is taken either once daily or once per week. Follow your doctor's dosing instructions very carefully. Take alendronate first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take alendronate only once per week, take it on the same day each week and always first thing in the morning. Take with a full glass (6 to 8 ounces) of plain water. Do not use coffee, tea, soda, juice, or mineral water. Do not eat or drink anything other than plain water. Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Do not crush, chew, or suck on an alendronate regular tablet. Swallow it whole. Dissolve the effervescent tablet in at least 4 ounces of water (at room temperature, not hot or cold). Let the tablet dissolve for 5 minutes. Stir this mixture for 10 seconds and drink all of it right away. Add a little more water to the glass, swirl gently and drink right away. For at least 30 minutes after taking alendronate: Do not lie down or recline. Do not take any other medicine including vitamins, calcium, or antacids. Pay special attention to your dental hygiene while taking alendronate. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using alendronate. Alendronate is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely. Store at room temperature away from moisture and heat. Keep unused effervescent tablets in the foil blister pack. Your doctor will determine how long to treat you with this medicine. Alendronate is often given for only 3 to 5 years.   What happens if I miss a dose? Once-daily dosing: If you forget to take alendronate first thing in the morning, do not take it later in the day. Wait until the following morning and skip the missed dose. Do not take two (2) doses in one day. Once-per-week dosing: If you forget to take alendronate on your scheduled day, take it first thing in the morning on the day after you remember the missed dose. Then return to your regular weekly schedule on your chosen dose day. Do not take 2 doses in one day. What happens if I overdose? Drink a full glass of milk and seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not make yourself vomit and do not lie down. What should I avoid while taking alendronate? Avoid taking any other medicines for at least 30 minutes after taking alendronate. This includes vitamins, calcium, and antacids. Some medicines can make it harder for your body to absorb alendronate. Avoid smoking, or try to quit. Smoking can reduce your bone mineral density, making fractures more likely. Avoid drinking large amounts of alcohol. Heavy drinking can also cause bone loss. Alendronate side effects Get emergency medical help if you have signs of an allergic reaction: hives; wheezing, difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using alendronate and call your doctor at once if you have: chest pain, new or worsening heartburn; difficulty or pain when swallowing; pain or burning under the ribs or in the back; severe heartburn, burning pain in your upper stomach, or coughing up blood; new or unusual pain in your thigh or hip; jaw pain, numbness, or swelling; severe joint, bone, or muscle pain; or low calcium levels--muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes). Common side effects may include: heartburn, upset stomach; stomach pain, nausea; diarrhea, constipation; or bone pain, muscle or joint pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect alendronate? Tell your doctor about all your other medicines, especially: aspirin; or NSAIDs (nonsteroidal anti-inflammatory drugs)--ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect alendronate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is alfuzosin? Alfuzosin is an alpha-adrenergic (AL-fa ad-ren-ER-Jk) blocker that is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate). Alfuzosin may also be used for purposes not listed in this medication guide. Warnings You should not take alfuzosin if you have moderate to severe liver disease. Many drugs can affect alfuzosin, and some should not be used at the same time. Tell your doctor about all your current medicines and any you start or stop using. Alfuzosin lowers blood pressure and may cause dizziness or fainting, especially if you take heart or blood pressure medications. Avoid driving or hazardous activity until you know how alfuzosin will affect you. Call your doctor at once if you feel light-headed feeling, like you might pass out. Before taking this medicine You should not take alfuzosin if you are allergic to it, or if you have: moderate to severe liver disease. Some medicines can cause unwanted or dangerous effects when used with alfuzosin. Your doctor may change your treatment plan if you also use: an antibiotic; antifungal medicine; heart medication; antiviral medicine to treat hepatitis C or HIV/AIDS; or medicines similar to alfuzosin (doxazosin, prazosin, silodosin, tamsulosin, or terazosin). Tell your doctor if you have ever had: low blood pressure, especially if caused by taking medications; liver disease; kidney disease; prostate cancer; or long QT syndrome (in you or a family member). Alfuzosin can affect your pupils. If you have cataract surgery, tell your surgeon ahead of time that you use alfuzosin. Alfuzosin is not for use in women, and the effects of this medicine during pregnancy or in breastfeeding women are unknown. Alfuzosin is not approved for use by anyone younger than 18 years old. How should I take alfuzosin? Your doctor may test your prostate specific antigen (PSA) to check for prostate cancer before you take alfuzosin. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Take alfuzosin just after a meal, at the same time each day. Do not take the medicine on an empty stomach. Swallow the tablet whole and do not crush, chew, or break it. Alfuzosin lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it. You may feel very dizzy when you first wake up. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Your blood pressure will need to be checked often. Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, or heavy sweating. Call your doctor if you are sick with vomiting or diarrhea. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking alfuzosin? Avoid driving or hazardous activity until you know how alfuzosin will affect you. Your reactions could be impaired. Drinking alcohol with this medicine can cause side effects. Alfuzosin side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; new or worsening chest pain; upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or penis erection that is painful or lasts 4 hours or longer. Common side effects may include: dizziness; headache; or feeling tired. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Alfuzosin dosing information Usual Adult Dose for Benign Prostatic Hyperplasia: Extended-release tablet: 10 mg orally once a day immediately after the same meal each day   What other drugs will affect alfuzosin? Tell your doctor about all your current medicines. Many drugs can increase your risk of very low blood pressure while taking alfuzosin, especially: heart or blood pressure medication; nitrate medication (such as nitroglycerin); or sildenafil (Viagra) and other erectile dysfunction medicines. This list is not complete. Many other drugs can affect alfuzosin, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

What is allopurinol? Allopurinol reduces the production of uric acid in the body. Uric acid buildup can lead to gout or kidney stones. Allopurinol is used to treat gout or kidney stones. Allopurinol is also used to decrease levels of uric acid in people who are receiving cancer treatment. Warnings Allopurinol can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Visit your doctor regularly. You should not use this medicine if you have ever had a serious allergic reaction to allopurinol. Stop taking the medicine and call your doctor at once if you have any signs of skin rash (no matter how mild), painful urination, blood in your urine, burning in your eyes, or swelling in your face or throat. Avoid drinking alcohol. It can make your condition worse. Allopurinol may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Allopurinol side effects Stop using this medicine and get emergency medical help if you have signs of an allergic reaction to allopurinol (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Stop using allopurinol and call your doctor at once if you have: any skin rash, no matter how mild; painful urination, blood in the urine; little or no urination; easy bruising, unusual bleeding; numbness, tingling, burning pain; worsening gout symptoms; or liver problems - loss of appetite, weight loss, stomach pain (upper right side), itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Common allopurinol side effects may include: an increase in gout attacks when you first starting taking allopurinol oral; rash; drowsiness; fever, chills; abnormal liver function tests; nausea, diarrhea; or joint pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Before taking this medicine You should not use allopurinol if you are allergic to it. To make sure allopurinol is safe for you, tell your doctor if you have ever had: kidney disease; liver disease; diabetes; congestive heart failure; high blood pressure; if you are receiving chemotherapy; or if you have a gene variation called HLA-B*58:01 allele (your doctor will test you for this). Tell your doctor if you are pregnant or breastfeeding. Do not give this medicine to a child without medical advice. How should I use allopurinol? Take allopurinol exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Take allopurinol oral with a full glass of water. To reduce your risk of kidney stones forming, drink 8 to 10 full glasses of fluid every day, unless your doctor tells you otherwise. If this medicine upsets your stomach, take allopurinol oral after a meal. Allopurinol injection is given as an infusion into a vein if you are unable to take the medicine by mouth. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself. You may need to mix the injection with a liquid (diluent) in an IV bag. When using injections by yourself, be sure you understand how to properly mix and store the medicine. Ask your doctor or pharmacist if you don't understand all instructions. Prepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine. You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if allopurinol is effective. You may have gout attacks more often when you first start taking this medicine oral. Your doctor may recommend other gout medication to take with allopurinol. Keep taking the medicine as directed. It may take 2 to 6 weeks before you have fewer gout attacks. Call your doctor if your symptoms do not improve after 6 weeks. You may need to follow a special diet to help prevent kidney stones. Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid. Store at room temperature away from moisture and heat. Dosing information Usual Adult Dose of Allopurinol for Gout: Dose will vary with the severity of the disease: Initial dose: 100 mg orally once a day -Increase in increments of 100 mg weekly until a serum uric level of 6 mg/dL or less is attained Mild Gout: -Average maintenance dose: 200 to 300 mg orally once a day Moderately Severe Tophaceous Gout: -Average maintenance dose: 400 to 600 mg orally/day in divided doses Minimal Effective Dose: 100 to 200 mg per day Maximum Dose: 800 mg per day Comments: -Oral doses in excess of 300 mg/day should be given in divided doses, preferably after meals to minimize gastric irritation. -A gradual dose titration is recommended to reduce the possibility of acute gouty attacks. -Normal serum urate levels are usually achieved in 1 to 3 weeks. Use: For the management of patients with signs and symptoms of primary or secondary gout (acute attacks, tophi, joint destruction, uric acid lithiasis, and/or nephropathy). Usual Adult Dose of Allopurinol for Hyperuricemia Secondary to Chemotherapy: Parenteral: 200 to 400 mg/m2/day IV as a single infusion or in equally divided infusions at 6, 8, or 12 hour intervals Maximum dose: 600 mg/day Oral: Initial dose: 600 to 800 mg orally in divided doses Maintenance: Adjust dose as needed based on serum uric acid levels Maximum dose: 800 mg per day Comments: -When possible, therapy should be initiated 24 to 48 hours before the start of chemotherapy; treatment should be discontinued when the potential for overproduction of uric acid is no longer present. -Oral doses in excess of 300 mg/day should be given in divided doses, preferably after meals to minimize gastric irritation. -The dose to lower serum uric acid to normal or near-normal varies with the severity of the disease; the above dosing represents suggested doses; serum uric acid levels should serve as an index. -Fluid intake should be sufficient to maintain a daily urinary output of at least 2 L; neutral or preferably slightly alkaline urine is desirable. Use: For the management of patients with leukemia, lymphoma, and malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels; IV therapy is available for patients who cannot tolerate oral therapy. Usual Adult Dose of Allopurinol for Calcium Oxalate Calculi with Hyperuricosuria: 200 to 300 mg orally once a day or in divided doses Comments: -Carefully assess risk versus benefit when initiating therapy and periodically thereafter. -Dose adjustments should be based on control of hyperuricosuria based on 24-hour urinary urate determinations. -Clinical experience suggests these patients may benefit dietary changes in addition to drug therapy. Use: For the management recurrent calcium oxalate calculi in patients whose daily uric acid excretion exceeds 800 mg/day in males or 750 mg/day in females. Usual Pediatric Dose for Hyperuricemia Secondary to Chemotherapy: Parenteral: Initial dose: 200 mg/m2/day IV as a single infusion or in equally divided infusions at 6, 8, or 12 hour intervals Maximum dose: 600 mg/day Oral: Age: Less than 6 years: 150 mg orally once a day or in divided doses Age: 6 to 10 years: 300 mg orally once a day or in divided doses Age: Greater than 10 years: 600 to 800 mg orally per day in divided doses -After 48 hours, evaluate and adjust dose as needed Comments: -Oral doses in excess of 300 mg should be administered in divided doses. -When possible, therapy should be initiated 24 to 48 hours before the start of chemotherapy; treatment should be discontinued when the potential for overproduction of uric acid is no longer present. -The dose to lower serum uric acid to normal or near-normal varies with the severity of the disease; the above dosing represents suggested doses in children; serum uric acid levels should serve as an index. -Fluid intake should be sufficient to maintain a daily urinary output of at least 2 L; neutral or preferably slightly alkaline urine is desirable. Use: For the management of patients with leukemia, lymphoma, and malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels.   What happens if I miss a dose? Take the allopurinol oral dose as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Call your doctor for instructions if you miss an injection. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using allopurinol? Avoid driving or hazardous activity until you know how allopurinol will affect you. Your reactions could be impaired. Avoid drinking alcohol. It may worsen your condition. What other drugs will affect allopurinol? Tell your doctor about all your other medicines, especially: azathioprine or mercaptopurine; chlorpropamide; cyclosporine; an antibiotic such as ampicillin or amoxicillin; a blood thinner such as warfarin, Coumadin, Jantoven; or a diuretic or "water pill". This list is not complete. Other drugs may interact with allopurinol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is alprazolam? Alprazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that it works by enhancing the activity of certain neurotransmitters in the brain. Alprazolam is used to treat anxiety disorders, panic disorders, and anxiety caused by depression. It is dangerous to purchase alprazolam on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. Warnings MISUSE OF ALPRAZOLAM CAN CAUSE ADDICTION, OVERDOSE, OR DEATH and should be used only by the person for whom it was prescribed. Keep the medication in a place where others cannot get to it. Alprazolam can slow or stop your breathing and fatal side effects can occur if you take this medicine with alcohol, opioid medicine, or other drugs that cause drowsiness or slow your breathing. Do not stop using this medicine without asking your doctor. You may have life-threatening withdrawal symptoms if you stop using the medicine suddenly after long-term use. Some withdrawal symptoms may last up to 12 months or longer. Get medical help right away if you stop using alprazolam and have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, or thoughts about suicide. You should not use alprazolam if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to alprazolam or similar medicines (Valium, Ativan, Tranxene, and others). Do not use alprazolam if you are pregnant. This medicine can cause birth defects or life-threatening withdrawal symptoms in a newborn. Before taking this medicine You should not take alprazolam if: you also take antifungal medicine such as itraconazole or ketoconazole; or you have a history of allergic reaction to any benzodiazepine (alprazolam, lorazepam, diazepam, Ativan, Valium, Versed, Klonopin, and others). To make sure alprazolam is safe for you, tell your doctor if you have ever had: breathing problems; drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease. Tell your doctor if you are pregnant or plan to become pregnant. If you use alprazolam during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks. You should not breastfeed. If you do breastfeed, tell your doctor if you notice drowsiness or feeding problems in the baby. Not approved for use by anyone younger than 18 years old. How should I take alprazolam? Take alprazolam exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides or instruction sheets. Never use alprazolam in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of alprazolam. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law. Measure liquid medicine with the supplied measuring device (not a kitchen spoon). Swallow the extended-release tablet whole and do not crush, chew, or break it. Allow the orally disintegrating tablet to dissolve in your mouth without chewing. Call your doctor if your symptoms do not improve, or if they get worse. If you use this medicine long-term, you may need frequent medical tests. Do not stop using alprazolam without asking your doctor. You may have life-threatening withdrawal symptoms if you stop using the medicine suddenly after long-term use. Store at room temperature away from moisture, heat, and light. Keep your medicine in a place where no one can use it improperly. Throw away any alprazolam liquid not used within 90 days. Dosing information Usual Adult Dose for Anxiety: Immediate-release tablets/orally disintegrating tablets (ODT): 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day Usual Adult Dose for Panic Disorder: Immediate-release tablets/ODTs: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours. Usual Geriatric Dose for Anxiety: Elderly or debilitated patients: Immediate-release tablets/ODTs: 0.25 mg orally administered 2 or 3 times a day. Usual Geriatric Dose for Panic Disorder: Elderly or debilitated patients: Immediate-release tablets/ODTs: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal if you take it with alcohol, opioid medicine, or other drugs that cause drowsiness or slow your breathing. Overdose symptoms may include severe drowsiness, confusion, slurred speech, muscle weakness, loss of balance or coordination, feeling light-headed, slow heartbeats, weak or shallow breathing, fainting, or coma. What should I avoid while taking alprazolam? Avoid drinking alcohol. Dangerous side effects or death could occur. Avoid driving or hazardous activity until you know how alprazolam will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Alprazolam side effects Get emergency medical help if you have signs of an allergic reaction to alprazolam: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Alprazolam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up. Call your doctor at once if you have: weak or shallow breathing; a light-headed feeling, like you might pass out; a seizure; hallucinations, risk-taking behavior; increased energy, decreased need for sleep; racing thoughts, being agitated or talkative; double vision; or jaundice (yellowing of the skin or eyes). Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury. Common alprazolam side effects may include: drowsiness; or feeling light-headed. After you stop using alprazolam, get medical help right away if you have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, suicidal thoughts or actions. Some withdrawal symptoms may last up to 12 months or longer after stopping this medicine suddenly. Tell your doctor if you have ongoing anxiety, depression, problems with memory or thinking, trouble sleeping, ringing in your ears, a burning or prickly feeling, or a crawling sensation under your skin. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect alprazolam? Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective. Taking alprazolam with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Many drugs can interact with alprazolam, and some drugs should not be used at the same time. Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

What is alprazolam? Alprazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that it works by enhancing the activity of certain neurotransmitters in the brain. Alprazolam is used to treat anxiety disorders, panic disorders, and anxiety caused by depression. It is dangerous to purchase alprazolam on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. Warnings MISUSE OF ALPRAZOLAM CAN CAUSE ADDICTION, OVERDOSE, OR DEATH and should be used only by the person for whom it was prescribed. Keep the medication in a place where others cannot get to it. Alprazolam can slow or stop your breathing and fatal side effects can occur if you take this medicine with alcohol, opioid medicine, or other drugs that cause drowsiness or slow your breathing. Do not stop using this medicine without asking your doctor. You may have life-threatening withdrawal symptoms if you stop using the medicine suddenly after long-term use. Some withdrawal symptoms may last up to 12 months or longer. Get medical help right away if you stop using alprazolam and have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, or thoughts about suicide. You should not use alprazolam if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to alprazolam or similar medicines (Valium, Ativan, Tranxene, and others). Do not use alprazolam if you are pregnant. This medicine can cause birth defects or life-threatening withdrawal symptoms in a newborn. Before taking this medicine You should not take alprazolam if: you also take antifungal medicine such as itraconazole or ketoconazole; or you have a history of allergic reaction to any benzodiazepine (alprazolam, lorazepam, diazepam, Ativan, Valium, Versed, Klonopin, and others). To make sure alprazolam is safe for you, tell your doctor if you have ever had: breathing problems; drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease. Tell your doctor if you are pregnant or plan to become pregnant. If you use alprazolam during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks. You should not breastfeed. If you do breastfeed, tell your doctor if you notice drowsiness or feeding problems in the baby. Not approved for use by anyone younger than 18 years old. How should I take alprazolam? Take alprazolam exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides or instruction sheets. Never use alprazolam in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of alprazolam. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law. Measure liquid medicine with the supplied measuring device (not a kitchen spoon). Swallow the extended-release tablet whole and do not crush, chew, or break it. Allow the orally disintegrating tablet to dissolve in your mouth without chewing. Call your doctor if your symptoms do not improve, or if they get worse. If you use this medicine long-term, you may need frequent medical tests. Do not stop using alprazolam without asking your doctor. You may have life-threatening withdrawal symptoms if you stop using the medicine suddenly after long-term use. Store at room temperature away from moisture, heat, and light. Keep your medicine in a place where no one can use it improperly. Throw away any alprazolam liquid not used within 90 days. Dosing information Usual Adult Dose for Anxiety: Immediate-release tablets/orally disintegrating tablets (ODT): 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day Usual Adult Dose for Panic Disorder: Immediate-release tablets/ODTs: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours. Usual Geriatric Dose for Anxiety: Elderly or debilitated patients: Immediate-release tablets/ODTs: 0.25 mg orally administered 2 or 3 times a day. Usual Geriatric Dose for Panic Disorder: Elderly or debilitated patients: Immediate-release tablets/ODTs: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal if you take it with alcohol, opioid medicine, or other drugs that cause drowsiness or slow your breathing. Overdose symptoms may include severe drowsiness, confusion, slurred speech, muscle weakness, loss of balance or coordination, feeling light-headed, slow heartbeats, weak or shallow breathing, fainting, or coma. What should I avoid while taking alprazolam? Avoid drinking alcohol. Dangerous side effects or death could occur. Avoid driving or hazardous activity until you know how alprazolam will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Alprazolam side effects Get emergency medical help if you have signs of an allergic reaction to alprazolam: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Alprazolam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up. Call your doctor at once if you have: weak or shallow breathing; a light-headed feeling, like you might pass out; a seizure; hallucinations, risk-taking behavior; increased energy, decreased need for sleep; racing thoughts, being agitated or talkative; double vision; or jaundice (yellowing of the skin or eyes). Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury. Common alprazolam side effects may include: drowsiness; or feeling light-headed. After you stop using alprazolam, get medical help right away if you have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, suicidal thoughts or actions. Some withdrawal symptoms may last up to 12 months or longer after stopping this medicine suddenly. Tell your doctor if you have ongoing anxiety, depression, problems with memory or thinking, trouble sleeping, ringing in your ears, a burning or prickly feeling, or a crawling sensation under your skin. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect alprazolam? Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective. Taking alprazolam with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Many drugs can interact with alprazolam, and some drugs should not be used at the same time. Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

What is amantadine? Amantadine is an antiviral medicine that blocks the actions of viruses in your body. Amantadine is used to treat Parkinson's disease and "Parkinson-like" symptoms such as stiffness or tremors, shaking, and repetitive uncontrolled muscle movements that may be caused by the use of certain drugs. Amantadine is also used to treat or prevent influenza A in adults and children. It may not be effective during every flu season because certain strains of the virus may be resistant to amantadine. This medicine should not be used in place of getting a yearly flu shot. The Centers for Disease Control recommends an annual flu shot to help protect you each year from new strains of influenza virus. Amantadine is available as tablets, capsules, and oral solution. Warnings You should not use amantadine if you received a nasal flu vaccine in the past 14 days. Do not receive a nasal flu vaccine while taking amantadine, and for at least 48 hours after your last dose. You may receive a flu shot (injection) while taking amantadine. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this amantadine affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs. Heat stroke has happened in people taking amantadine. Be careful in hot weather and during physical activity. If you have kidney problems, talk with your doctor. Your dose may need to be changed based on how well your kidneys work. Deaths have happened in people with kidney problems whose dose was too high for their kidney function. Do not stop taking amantadine all of a sudden without calling your doctor. You may have a greater risk of side effects. If you need to stop amantadine, you will want to slowly stop it as ordered by your doctor. Before taking this medicine You should not use amantadine if you are allergic to it, or if: you have severe kidney disease; or you received a "live" nasal flu vaccine (FluMist) within the past 14 days. To make sure amantadine is safe for you, tell your doctor if you have ever had: kidney disease; daytime drowsiness (caused by a sleep disorder or taking certain medicines); congestive heart failure; eczema; glaucoma; liver disease; a seizure; low blood pressure, fainting spells; alcoholism or drug addiction; or mental illness, psychosis, or suicidal thoughts or actions. People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for. It is not known whether amantadine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. You should not breast-feed while using this medicine. Amantadine is not approved for influenza in a child younger than 1 year old. Gocovri is not approved for use by anyone younger than 18 years old. How should I take amantadine? Take amantadine exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. If you take amantadine to treat influenza A, start taking the medicine within 24 to 48 hours after flu symptoms begin. Keep taking this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. You may take amantadine with or without food. You may need to take this medicine only at bedtime. Follow your doctor's instructions. Measure liquid oral solution carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Swallow the capsule or tablet whole and do not crush, chew, or break it. If you cannot swallow a capsule whole, open it and sprinkle the medicine into a spoonful of applesauce. Swallow the mixture right away without chewing. Do not save it for later use. Call your doctor if your symptoms do not improve, or if you have a fever with a headache, cough, skin rash, or other new symptoms. If you take amantadine for Parkinson symptoms: You should not stop using amantadine suddenly or your condition may become worse. Stopping suddenly may also cause unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine. Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.   What happens if I miss a dose? Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time. Call your doctor if you miss several doses in a row. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amantadine can be fatal. Overdose symptoms may include confusion, agitation, behavior changes, hallucinations, severe headache or pounding in your ears, muscle stiffness, problems with balance or walking, trouble breathing, fast heartbeats, or seizure. What to avoid Do not receive a nasal flu vaccine while using amantadine, and for at least 48 hours after your last dose. The vaccine may not work as well during this time, and may not protect you from influenza. You may receive a flu shot (injection) while taking amantadine. Do not drink alcohol. Dangerous side effects could occur. Avoid driving or operating machinery until you know how amantadine will affect you. Amantadine may impair your thinking or reactions. Some people taking this medicine have fallen asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with amantadine can increase your risk of unpleasant side effects. Amantadine side effects Get emergency medical help if you have signs of an allergic reaction to amantadine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: extreme drowsiness, falling asleep suddenly even after feeling alert; a light-headed feeling, like you might pass out; shortness of breath (even with mild exertion), swelling in your hands or feet; painful or difficult urination; depression, agitation, aggression, behavior changes, hallucinations, thoughts of hurting yourself; a seizure; or severe nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors. You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs. Side effects may be more likely in older adults. Common amantadine side effects may include: dizziness, falls; dry mouth; swelling in your legs or feet; nausea, constipation; or sleep problems (insomnia). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect amantadine? Using amantadine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: glaucoma medication; or medicine that contains sodium bicarbonate (such as Alka-Seltzer). This list is not complete. Other drugs may interact with amantadine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.  

What is amitriptyline?   Amitriptyline is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood. Amitriptyline is a prescription medicine used to treat symptoms of depression. Amitriptyline may also be used for purposes not listed in this medication guide.   Warnings You should not use amitriptyline if you have recently had a heart attack. Do not use amitriptyline if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. You may have thoughts about suicide when you first start taking an antidepressant such as amitriptyline, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Before taking this medicine You should not use this medicine if you are allergic to amitriptyline, or: if you have recently had a heart attack. Do not use amitriptyline if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. To make sure amitriptyline is safe for you, tell your doctor if you have ever had: bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination. Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Tell your doctor if you are pregnant or breastfeeding. Amitriptyline is not approved for use by anyone younger than 12 years old. How should I take amitriptyline? Take amitriptyline exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve. If you need surgery, tell your surgeon you currently use amitriptyline. You may need to stop for a short time. Do not stop using amitriptyline suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using amitriptyline. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. Dosing information Usual Adult Dose for Depression: OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression Usual Geriatric Dose for Depression: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression Usual Pediatric Dose for Depression: 12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal. Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma. What to avoid Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with amitriptyline. Avoid driving or hazardous activity until you know how amitriptyline will affect you. Your reactions could be impaired. Avoid exposure to sunlight or tanning beds. Amitriptyline can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Amitriptyline side effects Get emergency medical help if you have signs of an allergic reaction to amitriptyline: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: signs of a blood clot - sudden numbness or weakness, problems with vision or speech, swelling or redness in an arm or leg; unusual thoughts or behavior; a light-headed feeling, like you might pass out; chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; pounding heartbeats or fluttering in your chest; confusion, hallucinations; a seizure (convulsions); painful or difficult urination; severe constipation; easy bruising, unusual bleeding; or fever, chills, sore throat, mouth sores. Common amitriptyline side effects may include: constipation, diarrhea; nausea, vomiting, upset stomach; mouth pain, unusual taste, black tongue; appetite or weight changes; urinating less than usual; itching or rash; breast swelling (in men or women); or decreased sex drive, impotence, or difficulty having an orgasm. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect amitriptyline? Taking amitriptyline with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking amitriptyline with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Tell your doctor about all your other medicines, especially: other antidepressants; medicine to treat depression, anxiety, mood disorders, or mental illness; cold or allergy medicine (Benadryl and others); medicine to treat Parkinson's disease; medicine to treat stomach problems, motion sickness, or irritable bowel syndrome; medicine to treat overactive bladder; or bronchodilator asthma medication. This list is not complete. Other drugs may affect amitriptyline, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.  

What is amlodipine?   Amlodipine is a calcium channel blocker that dilates (widens) blood vessels and improves blood flow. Amlodipine is used to treat chest pain (angina) and other conditions caused by coronary artery disease. Amlodipine is also used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack. Amlodipine is for use in adults and children who are at least 6 years old. Warnings Before taking amlodipine, tell your doctor if you have congestive heart failure or liver disease. Drinking alcohol can further lower your blood pressure and may increase certain side effects of amlodipine. If you are being treated for high blood pressure, keep using amlodipine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Amlodipine is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely. Tell your doctor about all other heart or blood pressure medications you are taking. Your chest pain may become worse when you first start taking amlodipine or when your dose is increased. Call your doctor if your chest pain is severe or ongoing. Before taking this medicine You should not take amlodipine if you are allergic to it. To make sure amlodipine is safe for you, tell your doctor if you have ever had: liver disease; or a heart valve problem called aortic stenosis. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether amlodipine will harm an unborn baby. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby. Amlodipine can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breast-feeding. Amlodipine is not approved for use by anyone younger than 6 years old.   How should I take amlodipine? Take amlodipine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended. You may take amlodipine with or without food. Take the medicine at the same time each day. Shake the Katerzia oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Your blood pressure will need to be checked often. Your chest pain may become worse when you first start taking amlodipine or when your dose is increased. Call your doctor if your chest pain is severe or ongoing. If you are being treated for high blood pressure, keep using amlodipine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Your hypertension or heart condition may be treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or stop taking any of your medications without your doctor's advice. This is especially important if you also take nitroglycerin. Amlodipine is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely. Store at room temperature away from moisture, heat, and light.   What happens if I miss a dose? Take the missed dose as soon as you remember. If you are more than 12 hours late, skip the missed dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include rapid heartbeats, redness or warmth in your arms or legs, or fainting. What to avoid Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Amlodipine side effects Get emergency medical help if you have signs of an allergic reaction to amlodipine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. In rare cases, when you first start taking amlodipine, your angina may get worse or you could have a heart attack. Seek emergency medical attention or call your doctor right away if you have symptoms such as: chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. Call your doctor at once if you have: pounding heartbeats or fluttering in your chest; worsening chest pain; swelling in your feet or ankles; severe drowsiness; or a light-headed feeling, like you might pass out. Common amlodipine side effects may include: dizziness, drowsiness; feeling tired; stomach pain, nausea; or flushing (warmth, redness, or tingly feeling).   This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect amlodipine? Tell your doctor about all your current medicines and any you start or stop using, especially: nitroglycerin; simvastatin (Zocor, Simcor, Vytorin); or any other heart or blood pressure medications. This list is not complete. Other drugs may interact with amlodipine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.  

What is amlodipine and benazepril? Amlodipine is a calcium channel blocker. Amlodipine relaxes (widens) blood vessels and improves blood flow. Benazepril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Benazepril also widens blood vessels and also prevents the body from retaining water. Amlodipine and benazepril is a combination medicine used to treat high blood pressure (hypertension). Amlodipine and benazepril may also be used for purposes not listed in this medication guide. Warnings Do not use if you are pregnant. If you become pregnant, stop taking amlodipine and benazepril and tell your doctor right away. You should not use this medicine if you have ever had angioedema. Do not take this medicine within 36 hours before or after taking medicine that contains sacubitril (such as Entresto). If you have diabetes, do not use amlodipine and benazepril together with any medication that contains aliskiren (a blood pressure medicine). Before taking this medicine You should not use this medicine if you are allergic to amlodipine or benazepril, or if: you have had angioedema (hives or severe swelling of deep skin tissues sometimes caused by allergic reaction); you recently took a heart medicine called sacubitril; or you are allergic to any other ACE inhibitor, such as captopril, enalapril, lisinopril, moexipril, benazepril, quinapril, ramipril, Accupril, Prinivil, Mavik, Vasotec, and many others. Do not take amlodipine and benazepril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto). If you have diabetes, do not use amlodipine and benazepril together with any medication that contains aliskiren (a blood pressure medicine). You may also need to avoid taking amlodipine and benazepril with aliskiren if you have kidney disease. Tell your doctor if you have ever had: heart disease or congestive heart failure; high levels of potassium in your blood (hyperkalemia); kidney disease (or if you are on dialysis); liver disease; or if you are on a low-salt diet. Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Benazepril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. You should not breast-feed while you are using this medicine. How should I take amlodipine and benazepril? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. You may take amlodipine and benazepril with or without food. Take the medicine at the same time each day. Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. Drink plenty of water each day while you are taking amlodipine and benazepril. Your blood pressure will need to be checked often, and you may also need frequent blood tests. If you need surgery, tell your surgeon you currently use this medicine. You may need to stop for a short time. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking amlodipine and benazepril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if you are more than 12 hours late for the dose. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking amlodipine and benazepril? Drinking alcohol with amlodipine and benazepril can cause side effects. Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Do not use salt substitutes or potassium supplements while taking amlodipine and benazepril, unless your doctor has told you to. Amlodipine and benazepril side effects Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. You may be more likely to have an allergic reaction if you are African-American. Some side effects may not occur until after you have used the medicine for several months. Call your doctor at once if you have: a light-headed feeling, like you might pass out; swelling in your hands or feet, rapid weight gain; new or worsened chest pain; fever, chills, sore throat, body aches, flu symptoms; high potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or liver problems--nausea, stomach pain (upper right side), itching, unusual tiredness, flu-like symptoms, dark urine, jaundice (yellowing of the skin or eyes). Common side effects may include: cough; dizziness; or swelling in your hands or feet. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Amlodipine and benazepril dosing information Usual Adult Dose for Hypertension: Initial dose: Amlodipine 2.5 mg-Benazepril 10 mg orally once a day Maintenance dose: Amlodipine 2.5 to 10 mg-Benazepril 10 to 40 mg orally once a day Maximum dose: Amlodipine: 10 mg/day; Benazepril 80 mg/day Comments: -May increase dose after 2 weeks as needed to achieve blood pressure goal. -Adding benazepril to amlodipine should not be expected to provide additional blood pressure reduction in African Americans.   What other drugs will affect amlodipine and benazepril? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Tell your doctor about all your current medicines. Many drugs can affect amlodipine and benazepril, especially: lithium; probenecid; simvastatin; a diuretic or "water pill"; gold injections to treat arthritis; heart or blood pressure medication; insulin or oral diabetes medicine; an antibiotic--clarithromycin, telithromycin; antifungal medicine--itraconazole, ketoconazole; antiviral medicine to treat HIV/AIDS--indinavir, ritonavir, and others; medicine to prevent organ transplant rejection--cyclosporine, everolimus, sirolimus, tacrolimus, temsirolimus; or NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete and many other drugs may affect amlodipine and benazepril. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is amlodipine and olmesartan? Amlodipine is a calcium channel blocker. Olmesartan is an angiotensin II receptor blocker (sometimes called an ARB). Amlodipine and olmesartan is a combination medicine used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack. Amlodipine and olmesartan may also be used for purposes not listed in this medication guide. Warnings Do not use if you are pregnant. If you become pregnant, stop taking amlodipine and olmesartan and tell your doctor right away. If you have diabetes, do not use amlodipine and olmesartan together with any medication that contains aliskiren (a blood pressure medicine). Before taking this medicine You should not use this medicine if you are allergic to amlodipine or olmesartan. If you have diabetes, do not use amlodipine and olmesartan together with any medication that contains aliskiren (a blood pressure medicine). You may also need to avoid taking amlodipine and olmesartan with aliskiren if you have kidney disease. Tell your doctor if you have ever had: kidney disease; liver disease; coronary artery disease; angina (chest pain), congestive heart failure; high levels of potassium in your blood; if you are on a low-salt diet; if you are 75 years or older; or if you recently had a heart attack. Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Olmesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. You should not breastfeed while using this medicine. Amlodipine and olmesartan is not approved for use by anyone younger than 18 years old. How should I take amlodipine and olmesartan? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. You may take this medication with or without food. Your blood pressure will need to be checked often. Your kidney function may also need to be checked. Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, or heavy sweating. Call your doctor if you are sick with vomiting or diarrhea. If you need surgery, tell the surgeon ahead of time that you are using amlodipine and olmesartan. Keep using amlodipine and olmesartan as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking amlodipine and olmesartan? Avoid driving or hazardous activity until you know how amlodipine and olmesartan will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Do not use potassium supplements or salt substitutes, unless your doctor has told you to. Amlodipine and olmesartan side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. When you first start taking this medicine, you may have new or worsening chest pain (angina), or you could have a heart attack. Seek emergency medical attention or call your doctor right away if you have symptoms such as: chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating. Call your doctor at once if you have: new or worsening chest pain; swelling in your hands or feet, rapid weight gain; severe or ongoing diarrhea with weight loss; pounding heartbeats or fluttering in your chest; a light-headed feeling, like you might pass out; or high potassium level--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement. Common side effects include swelling. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Amlodipine and olmesartan dosing information Usual Adult Dose for Hypertension: Initial dose: Amlodipine 5 mg-Olmesartan 20 mg orally once a day; may increase dose after 1 to 2 weeks of therapy. Maximum dose: Amlodipine 10 mg-Olmesartan 40 mg orally once a day Uses: -Substitution therapy for patients maintained on the individual components separately or for patients not adequately controlled with one of the components or a component within the same antihypertensive class. -Initial therapy in patients who are likely to need more than 1 antihypertensive agent to control blood pressure.   What other drugs will affect amlodipine and olmesartan? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. If you also take colesevelam, take it 4 hours after you take amlodipine and olmesartan. Tell your doctor about all your other medicines, especially: cyclosporine; lithium; simvastatin; tacrolimus; or NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect amlodipine and olmesartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is amlodipine and valsartan? Amlodipine is a calcium channel blocker. Valsartan is an angiotensin II receptor antagonist. Amlodipine and valsartan is a combination medicine used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack. Amlodipine and valsartan is usually given after other blood pressure medicines have been tried without success. Amlodipine and valsartan may also be used for purposes not listed in this medication guide. Warnings Do not use if you are pregnant. If you become pregnant, stop taking amlodipine and valsartan and tell your doctor right away. If you have diabetes, do not use amlodipine and valsartan together with any medication that contains aliskiren (a blood pressure medicine). Before taking this medicine You should not use this medicine if you are allergic to amlodipine (Norvasc) or valsartan (Diovan). If you have diabetes, do not use amlodipine and valsartan together with any medication that contains aliskiren (a blood pressure medicine). You may also need to avoid taking amlodipine and valsartan with aliskiren if you have kidney disease. Tell your doctor if you have ever had: heart problems; a heart attack; kidney disease; liver disease; or if you are on a low-salt diet. Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Amlodipine and valsartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. You should not breastfeed while using this medicine. Amlodipine and valsartan is not approved for use by anyone younger than 18 years old. How should I take amlodipine and valsartan? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. You may take this medication with or without food. Your blood pressure will need to be checked often. Your kidney function may also need to be checked. You may have very low blood pressure while taking this medication. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. If you need surgery, tell the surgeon ahead of time that you are using amlodipine and valsartan. It may take up to 4 weeks for this medication to control your blood pressure. Keep using amlodipine and valsartan as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Blood pressure medication is only part of a complete treatment program that may also include diet, exercise, regular blood pressure checks, lifestyle changes, and other medications. Follow your doctor's instructions very carefully. Use all medications as directed by your doctor. Do not change your doses or stop taking any of your medications without your doctor's advice. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking amlodipine and valsartan? Do not use potassium supplements or salt substitutes, unless your doctor has told you to. Drinking alcohol with amlodipine and valsartan can cause side effects. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Amlodipine and valsartan side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; swelling in your hands or feet, rapid weight gain; or high potassium level--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement. Common side effects include: swelling in your hands or feet; dizziness; or cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Amlodipine and valsartan dosing information Usual Adult Dose for Hypertension: Initial therapy: Amlodipine 5 mg-Valsartan 160 mg orally once a day Add-on/Replacement therapy: Amlodipine 5 to 10 mg-Valsartan 160 to 320 mg orally once a day Comments: -May increase dose after 1 to 2 weeks of therapy. -A patient who experiences dose-limiting adverse reactions on either component alone may be switched to this drug containing a lower dose of that component in combination with the other. If blood pressure remains uncontrolled after 3 to 4 weeks, may titrate up to a maximum of amlodipine 10 mg-valsartan 320 mg orally once a day.   What other drugs will affect amlodipine and valsartan? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Tell your doctor about all your current medicines. Many drugs can affect amlodipine and valsartan, especially: cyclosporine; lithium; simvastatin or other cholesterol medication; an antibiotic or antifungal medicine; heart or blood pressure medication, including a diuretic ("water pill"); or NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), and others. This list is not complete and many other drugs may affect amlodipine and valsartan. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is amoxapine? Amoxapine is a tricyclic antidepressant that is used to treat symptoms of depression, anxiety, or agitation. Amoxapine may also be used for purposes not listed in this medication guide. Warnings You should not use amoxapine if you have recently had a heart attack. Do not use amoxapine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor. Before taking this medicine You should not use amoxapine if you are allergic to it, or if: you have recently had a heart attack. Do not use trimipramine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Tell your doctor if you have ever had: heart disease, stroke, or seizures; kidney disease; schizophrenia or other mental illness; diabetes (amoxapine may raise or lower blood sugar); bipolar disorder (manic depression); if you are receiving electroshock treatment; glaucoma; or problems with urination. Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Tell your doctor if you are pregnant or breastfeeding. Amoxapine is not approved for use by anyone younger than 18 years old. How should I take amoxapine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. If you take amoxapine once daily, take your dose at bedtime. It may take up to 3 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve. Do not stop using amoxapine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using trimipramine. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amoxapine can be fatal. Overdose symptoms may include seizure (convulsions), acidosis, or coma. What should I avoid while taking amoxapine? Drinking alcohol with amoxapine can cause side effects. Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Amoxapine side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: skin rash, fever; uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); pounding heartbeats or fluttering in your chest; chest pain or pressure, pain spreading to your jaw or shoulder; sudden numbness or weakness (especially on one side of the body), slurred speech, problems with vision or balance; or severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out. Common side effects may include: drowsiness; constipation; dry mouth; or blurred vision. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Amoxapine dosing information Usual Adult Dose for Depression: Initial dose: 50 mg orally 2 to 3 times a day Maintenance dose: 100 mg orally 2 to 3 times a day Maximum dose: 600 mg/day Comments: -Increases above 300 mg/day should be made only if 300 mg/day has been ineffective during at least two weeks. -Hospitalized patients who have been refractory to antidepressant treatment and who have no history of convulsive seizures may have dosage increased cautiously up to 600 mg/day in divided doses. -This drug may be given in a single daily dose, not to exceed 300 mg, preferably at bedtime. -Doses above 300 mg should be given in divided doses. Uses: -Relief of symptoms of depression in patients with neurotic or reactive depressive disorders as well as endogenous and psychotic depression -Depression accompanied by agitation or anxiety Usual Geriatric Dose for Depression: Initial dose: 25 mg orally 2 to 3 times a day Maintenance dose: 50 mg orally 2 to 3 times a day Maximum dose: 300 mg/day Comments: -Once an effective dosage is established, this drug may be administered in a single bedtime dose, not to exceed 300 mg. -Recommended maintenance dosage is the lowest dose that will maintain remission. -If symptoms reappear, the dosage should be increased to previous level until symptoms are under control. Use: -Relief of symptoms of depression in patients with neurotic or reactive depressive disorders as well as endogenous and psychotic depression -Depression accompanied by agitation or anxiety   What other drugs will affect amoxapine? Using amoxapine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Many drugs can affect amoxapine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is anastrozole? Anastrozole lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body. Anastrozole is used to treat breast cancer in postmenopausal women. It is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox). Anastrozole may also be used for purposes not listed in this medication guide. Warnings Anastrozole may decrease blood flow to your heart, especially if you have ever had coronary artery disease (clogged arteries). Seek medical attention if you have new or worsening chest pain, or if you feel short of breath. Before taking this medicine You should not use anastrozole if you are allergic to it, or if you have not yet completed menopause. Anastrozole is not approved for use in men or children. You should not take anastrozole if you also take tamoxifen. Tell your doctor if you have ever had: heart problems; coronary artery disease (clogged artery disease); high cholesterol; or osteoporosis or low bone mineral density. Hormonal cancer treatment can weaken your bones. You may be more likely to have a broken bone while using anastrozole. Talk with your doctor about ways to keep your bones healthy. Although it is not likely that a postmenopausal woman would be pregnant, anastrozole may harm an unborn baby. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control if you are not past menopause. Keep using birth control for at least 3 weeks after your last dose of anastrozole. Tell your doctor if you become pregnant. Do not breastfeed while using anastrozole, and for at least 2 weeks after your last dose. How should I take anastrozole? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Anastrozole is usually taken once per day. Follow your doctor's dosing instructions very carefully. You may take anastrozole with or without food. You may need to keep taking this medication for up to 5 years. Follow your doctor's instructions. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking anastrozole? Avoid driving or hazardous activity until you know how anastrozole will affect you. Your reactions could be impaired. Anastrozole side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Anastrozole may decrease blood flow to your heart, especially if you have ever had coronary artery disease (clogged arteries). Seek medical attention if you have new or worsening chest pain, or if you feel short of breath. Call your doctor at once if you have: shortness of breath (even with mild exertion), swelling, rapid weight gain; numbness, prickly feeling, pain, or weakness in your hands or wrists; symptoms of bone fracture--bruising, swelling, tenderness, pain that worsens with movement; liver problems--right-sided upper stomach pain, yellowing of your skin or eyes, and not feeling well; or signs of a stroke--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance. Common side effects may include: numbness, tingling, or tickling feeling in your skin; hot flashes; weakness; joint pain or stiffness; bone pain, risk of fracture; swelling in your arms, legs, or feet; sore throat, cough, shortness of breath; headache, back pain; depression, sleep problems (insomnia); high blood pressure; nausea, vomiting; or rash. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Anastrozole dosing information Usual Adult Dose for Breast Cancer: Initial dose: 1 mg orally taken once a day Duration of therapy: Until tumor progression (treatment of advanced breast cancer); unknown (adjuvant treatment of early breast cancer) Uses: -Adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer; -First-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor unknown locally advanced or metastatic breast cancer; -Second-line treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy.   What other drugs will affect anastrozole? Anastrozole may not work as well if you take it together with an estrogen medication (such as hormone replacement therapy, estrogen creams, or birth control pills, injections, implants, skin patches, and vaginal rings or vaginal suppositories). Other drugs may affect anastrozole, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is aripiprazole? Aripiprazole is an antipsychotic medicine that is used to treat schizophrenia in adults and children at least 13 years old. Aripiprazole is also used in children 6 years or older who have Tourette's disorder, or symptoms of autistic disorder (irritability, aggression, mood swings, temper tantrums, and self-injury). Aripiprazole is used alone or with a mood stabilizer medicine to treat bipolar I disorder (manic depression) in adults and children at least 10 years old. Aripiprazole is used with antidepressant medication to treat major depressive disorder in adults. Warnings Aripiprazole is not approved for use in older adults with dementia-related psychosis. People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide. Do not stop using aripiprazole suddenly, or you could have unpleasant withdrawal symptoms. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how aripiprazole affects you. High blood sugar or diabetes, high cholesterol, and weight gain have happened with drugs like this one. These may raise the chance of heart and brain blood vessel disease. Low white blood cell counts have happened with drugs like this one. This may lead to a higher chance of infection. Rarely, infections have been deadly. Tell your doctor if you have ever had a low white blood cell count. Call your doctor right away if you have signs of infection like fever, chills, or sore throat. Before taking this medicine You should not take aripiprazole if you are allergic to it. Aripiprazole may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. To make sure aripiprazole is safe for you, tell your doctor if you have:: heart problems or a stroke; high or low blood pressure; diabetes (in you or a family member); seizures; or low white blood cell (WBC) counts. People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Stay alert to changes in your mood or symptoms. Your family or caregivers should also watch for sudden changes in your behavior. The liquid form (oral solution) of this medication contains sugar. Before taking aripiprazole oral solution, tell your doctor if you have diabetes. Aripiprazole can cause high blood sugar (hyperglycemia). If you are diabetic, check your blood sugar levels carefully. The orally disintegrating tablet form of this medication may contain over 3 milligrams of phenylalanine per tablet. Before taking Abilify Discmelt, tell your doctor if you have phenylketonuria (PKU). Taking antipsychotic medicine in the last 3 months of pregnancy may cause serious problems in the newborn. Tell your doctor right away if you get pregnant. Do not stop the medicine without your doctor's advice. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of aripiprazole on the baby. Ask a doctor if it is safe to breastfeed while using aripiprazole. How should I take aripiprazole? Take aripiprazole exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Aripiprazole can be taken with or without food. Swallow the regular tablet whole and do not crush, chew, or break it. Do not split the orally disintegrating tablet. Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).. Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves. If needed, you may drink liquid to help swallow the dissolved tablet. Your doctor will need to check your progress on a regular basis. If you also use antidepressant medicine, do not stop using it suddenly or you could have unpleasant symptoms. Ask your doctor before stopping the antidepressant. Store at room temperature away from moisture and heat. Aripiprazole liquid may be used for up to 6 months after opening, but not after the expiration date on the medicine label.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include drowsiness, vomiting, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma. What should I avoid while taking aripiprazole? Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid driving or hazardous activity until you know how aripiprazole will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid drinking alcohol. Dangerous side effects could occur. While taking aripiprazole, you may be more sensitive to very hot conditions. Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. Aripiprazole side effects Get emergency medical help if you have signs of an allergic reaction to aripiprazole: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Tell your doctor right away if you have new or sudden changes in mood or behavior, including new or worse depression or anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, more active or talkative, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: severe agitation, distress, or restless feeling; twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs; mask-like appearance of the face, trouble swallowing, problems with speech; seizure (convulsions); severe nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out; low blood cell counts - fever, chills, sore throat, weakness, easy bruising, unusual bleeding, purple or red spots under your skin; or high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor. You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs. Common aripiprazole side effects may include: blurred vision; increased saliva or drooling; muscle stiffness; uncontrolled muscle movements, shaking, anxiety, feeling restless; weight gain; nausea, vomiting, constipation; increased or decreased appetite; headache, dizziness, drowsiness, feeling tired; sleep problems (insomnia); or cold symptoms such as stuffy nose, sneezing, sore throat; This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect aripiprazole? Taking aripiprazole with other drugs that make you drowsy or slow your breathing can cause dangerous side effects or death. Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective. Many drugs can interact with aripiprazole. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all other medicines you use.

What is armodafinil? Armodafinil is a medication that promotes wakefulness. Armodafinil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. Armodafinil may also be used for purposes not listed in this medication guide. Warnings You should not use armodafinil if you have ever had a rash or allergic reaction caused by armodafinil or modafinil (Provigil). Stop taking armodafinil and call your doctor if you have a skin rash, no matter how mild. Other signs of a severe reaction include fever, swelling in your face or tongue, mouth sores, trouble breathing, swelling in your legs, yellowing of your skin or eyes, and skin rash or blistering sores. Before taking this medicine You should not use this medicine if you are allergic to armodafinil or modafinil (Provigil). To make sure armodafinil is safe for you, tell your doctor if you have ever had: liver or kidney disease; a heart muscle or valve disorder such as mitral valve prolapse; high blood pressure, heart disease, or prior heart attack; mental illness or psychosis; or drug or alcohol addiction. It is not known whether armodafinil will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Use a barrier form of birth control (condom or diaphragm with spermicide). Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during your treatment. It is not known whether armodafinil passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding. Armodafinil is not approved for use by anyone younger than 17 years old. How should I take armodafinil? Follow all directions on your prescription label. Do not take armodafinil in larger or smaller amounts or for longer than recommended. Armodafinil may be habit-forming. Never share armodafinil with another person, especially someone with a history of drug abuse or addiction. Selling or giving away armodafinil is against the law. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Armodafinil is usually taken each morning to prevent daytime sleepiness, or 1 hour before the start of a work shift to treat work-time sleep disorders. You may take armodafinil with or without food. Armodafinil is usually given for up to 12 weeks. Follow your doctor's instructions. If you are taking armodafinil to treat sleepiness caused by obstructive sleep apnea, you may also be treated with a continuous positive airway pressure (CPAP) machine. This machine is an air pump connected to mask that gently blows pressurized air into your nose while you sleep. The pump does not breathe for you, but the gentle force of air helps keep your airway open to prevent obstruction. Do not stop using your CPAP machine during sleep unless your doctor tells you to. The combination of treatment with CPAP and armodafinil may be necessary to best treat your condition. Taking this medication does not take the place of getting enough sleep. Talk with your doctor if you continue to have excessive sleepiness even while taking armodafinil. Armodafinil will not cure obstructive sleep apnea or treat its underlying causes. Follow your doctor's instructions about all your other treatments for this disorder. Store at room temperature away from moisture and heat. Keep track of your medicine. Armodafinil is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. What happens if I miss a dose? Take the missed dose as soon as you remember, but avoid taking the medication if you do not plan to be awake for several hours. If it is close to your normal bedtime hour, you may need to skip the missed dose and wait until the next day to take the medicine again. Talk with your doctor about what to do if you miss a dose of armodafinil. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, diarrhea, confusion, feeling restless or excited, fast or slow heart rate, chest pain, trouble sleeping, or hallucinations (seeing or hearing things that are not real). What should I avoid while taking armodafinil? Armodafinil may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid other dangerous activity until you know how this medication will affect your level of wakefulness. Avoid drinking alcohol while taking armodafinil. Armodafinil side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). Skin rashes serious enough to require hospitalization have occurred in people using a medicine similar to armodafinil. These rashes usually occurred within 1 to 5 weeks after the first dose. Stop taking armodafinil and call your doctor at the first sign of any skin rash, no matter how minor you think it might be. Seek medical treatment if you have symptoms of a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, unusual bruising, or jaundice (yellowing of your skin or eyes). Stop using armodafinil and call your doctor at once if you have: bruising, severe tingling, numbness, pain, muscle weakness; unusual bleeding (nosebleeds, bleeding gums); skin sores or blistering; mouth sores, trouble swallowing; chest pain, uneven heart beats; or depression, anxiety, hallucinations, aggression, unusual thoughts or behavior, suicidal thoughts. Common side effects may include: headache, dizziness; nausea; or sleep problems (insomnia). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Armodafinil dosing information Usual Adult Dose for Narcolepsy: 150 to 250 mg orally once a day in the morning Comments: -In obstructive sleep apnea (OSA), doses up to 250 mg/day have been well-tolerated but there is no consistent evidence of additional benefit beyond the 150 mg/day. -This drug is not a treatment for the underlying obstruction in OSA. -In cases where continuous positive airway pressure (CPAP) is the treatment of choice for excessive sleepiness, a maximal effort to treat with CPAP for an adequate period of time should be made prior to initiating this drug. Uses: To improve wakefulness in patients with excessive sleepiness associated with OSA and narcolepsy. Usual Adult Dose for Obstructive Sleep Apnea/Hypopnea Syndrome: 150 to 250 mg orally once a day in the morning Comments: -In obstructive sleep apnea (OSA), doses up to 250 mg/day have been well-tolerated but there is no consistent evidence of additional benefit beyond the 150 mg/day. -This drug is not a treatment for the underlying obstruction in OSA. -In cases where continuous positive airway pressure (CPAP) is the treatment of choice for excessive sleepiness, a maximal effort to treat with CPAP for an adequate period of time should be made prior to initiating this drug. Uses: To improve wakefulness in patients with excessive sleepiness associated with OSA and narcolepsy. Usual Adult Dose for Shift Work Sleep Disorder: 150 mg orally once a day approximately 1 hour prior to the start of the work shift Use: To improve wakefulness in patients with excessive sleepiness associated with shift work disorder.   What other drugs will affect armodafinil? Taking armodafinil with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking a sleeping pill, narcotic medication, muscle relaxer, or medicine for anxiety, depression, or seizures. Other drugs may interact with armodafinil, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What is aspirin?   Aspirin is a salicylate (sa-LIS-il-ate). It works by reducing substances in the body that cause pain, fever, and inflammation. Aspirin is used to treat pain, and reduce fever or inflammation. It is sometimes used to treat or prevent heart attacks, strokes, and chest pain (angina). Aspirin should be used for cardiovascular conditions only under the supervision of a doctor. Warnings You should not use aspirin if you have a bleeding disorder such as hemophilia, a recent history of stomach or intestinal bleeding, or if you are allergic to an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others. Do not give this medication to a child or teenager with a fever, flu symptoms, or chickenpox. Salicylates can cause Reye's syndrome, a serious and sometimes fatal condition in children. Before taking this medicine Do not give this medicine to a child or teenager with a fever, flu symptoms, or chickenpox. Aspirin can cause Reye's syndrome, a serious and sometimes fatal condition in children. You should not use aspirin if you are allergic to it, or if you have: a recent history of stomach or intestinal bleeding; a bleeding disorder such as hemophilia; or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others. To make sure this medicine is safe for you, tell your doctor if you have: asthma or seasonal allergies; stomach ulcers; liver disease; kidney disease; a bleeding or blood clotting disorder; gout; or heart disease, high blood pressure, or congestive heart failure. Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery. Tell your doctor if you are pregnant or plan to become pregnant.   Aspirin can pass into breast milk and may harm a nursing baby. You should not breastfeed while using this medicine. How should I take aspirin? Take aspirin exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Always follow directions on the medicine label about giving aspirin to a child. Take with food if aspirin upsets your stomach. You must chew the chewable tablet before you swallow it. Do not crush, chew, break, or open an enteric-coated or delayed/extended-release pill. Swallow the pill whole. If you need surgery, tell the surgeon ahead of time that you are using this medicine. You may need to stop using it for a short time. Do not use aspirin if you smell a strong vinegar odor in the bottle. The medicine may no longer be effective. Store at room temperature away from moisture and heat.   What happens if I miss a dose?   Since aspirin is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include stomach pain, vomiting, diarrhea, vision or hearing problems, fast or slow breathing, or confusion. What to avoid Avoid drinking alcohol while you are taking aspirin. Heavy drinking can increase your risk of stomach bleeding. If you are taking this medicine to prevent heart attack or stroke, avoid also taking ibuprofen (Advil, Motrin). Ibuprofen may make this medicine less effective in protecting your heart and blood vessels. If you must use both medications, ask your doctor how far apart your doses should be. Ask a doctor or pharmacist before using any cold, allergy, or pain medication. Many medicines available over the counter contain aspirin or an NSAID. Taking certain products together can cause you to get too much of this type of medication. Check the label to see if a medicine contains aspirin, ibuprofen, ketoprofen, naproxen, or an NSAID. Aspirin side effects Get emergency medical help if you have signs of an allergic reaction to aspirin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have: ringing in your ears, confusion, hallucinations, rapid breathing, seizure (convulsions); severe nausea, vomiting, or stomach pain; bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; fever lasting longer than 3 days; or swelling, or pain lasting longer than 10 days.   Common aspirin side effects may include: upset stomach, heartburn; drowsiness; or mild headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.  

What is atenolol? Atenolol (Tenormin) is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins). Atenolol is used to treat angina (chest pain) and hypertension (high blood pressure). Atenolol is also used to lower the risk of death after a heart attack. Warnings You should not use this atenolol if you have a serious heart condition such as "AV block," very slow heartbeats, or heart failure. Do not stop taking atenolol without first talking to your doctor. Stopping suddenly may make your condition worse. If you are having any type of surgery, be sure the surgeon knows ahead of time that you are using this medicine. Atenolol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking this medicine. Atenolol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension. If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Before taking this medicine You should not use atenolol if you are allergic to it, or if you have: a serious heart condition such as "AV block" (second or third degree); slow heartbeats; heart failure; or if your heart cannot pump blood properly. To make sure atenolol is safe for you, tell your doctor if you have: congestive heart failure; coronary artery disease (hardened arteries); asthma, bronchitis, emphysema; diabetes; overactive thyroid; liver or kidney disease; pheochromocytoma (tumor of the adrenal gland); peripheral vascular disease such as Raynaud's syndrome; or allergies (or if you are undergoing allergy treatments or skin-testing). Atenolol may harm an unborn baby. Tell your doctor if you are pregnant or if you become pregnant while using this medicine. Atenolol can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breastfeeding a baby. Atenolol is not approved for use by anyone younger than 18 years old. How should I take atenolol? Take atenolol exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Your blood pressure will need to be checked often. If you need surgery, tell the surgeon ahead of time that you are using atenolol. You may need to stop using the medicine for a short time. Keep using the medication as directed and tell your doctor if your symptoms do not improve. You should not stop taking atenolol suddenly. Stopping suddenly may make your condition worse. If you are being treated for high blood pressure: Keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Your condition may need to be treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. Atenolol dosing information Usual Adult Dose of Atenolol for Hypertension: Initial dose: 50 mg orally once a day Maintenance dose: 50 to 100 mg orally once a day Maximum dose: 100 mg per day Comments: -If desired response not achieved after 1 to 2 weeks, increase to 100 mg may be beneficial. -Doses greater than 100 mg once a day did not result in significant additional antihypertensive effects. Use: For the treatment of hypertension alone or in combination with other antihypertensive agents. Usual Adult Dose of Atenolol for Angina Pectoris Prophylaxis: Initial dose: 50 mg orally once a day -Increase to 100 mg orally once a day after 1 week if optimal response not achieved Maintenance dose: 50 to 200 mg orally once a day Maximum dose: 200 mg per day Comments: -Some patients may require 200 mg per day to attain optimal effect. Use: For the long-term management of angina pectoris due to coronary atherosclerosis. Usual Adult Dose of Atenolol for Angina Pectoris: Initial dose: 50 mg orally once a day -Increase to 100 mg orally once a day after 1 week if optimal response not achieved Maintenance dose: 50 to 200 mg orally once a day Maximum dose: 200 mg per day Comments: -Some patients may require 200 mg per day to attain optimal effect. Use: For the long-term management of angina pectoris due to coronary atherosclerosis. Usual Adult Dose of Atenolol for Myocardial Infarction: 50 mg orally twice a day or 100 mg orally once a day Comments: -If IV beta blockers are contraindicated or inappropriate, oral therapy should continue for at least 7 days post-myocardial infarction (MI). -Treatment with beta blockers post MI should generally continue for 1 to 3 years if there are no contraindications. Use: For the management of hemodynamically stable patients with definite or suspected acute myocardial infarction to reduce cardiovascular mortality. Usual Geriatric Dose of Atenolol for Hypertension: Initial dose: Consider reducing the starting dose to 25 mg orally once a day Detailed Atenolol dosage information What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include extreme weakness or lack of energy, very slow heart rate, shortness of breath, or fainting. What should I avoid while taking atenolol? Follow your doctor's instructions about any restrictions on food, beverages, or activity. Atenolol side effects Get emergency medical help if you have signs of an allergic reaction to atenolol: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: new or worsening chest pain; slow or uneven heartbeats; a light-headed feeling, like you might pass out; shortness of breath (even with mild exertion), swelling, rapid weight gain; or a cold feeling in your hands and feet. Common atenolol side effects may include include: cold hands or feet; dizziness; tiredness; or depressed mood. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect atenolol? Tell your doctor about all your current medicines and any you start or stop using, especially: digoxin, digitalis; indomethacin; any other beta-blocker--bisoprolol, carvedilol, labetalol, metoprolol, nebivolol, propranolol, sotalol, timolol, and others; or heart or blood pressure medication--amiodarone, clonidine, diltiazem, disopyramide, nicardipine, nifedipine, reserpine, verapamil, and others. This list is not complete. Other drugs may interact with atenolol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.