What is bethanechol? Bethanechol is used to treat urinary retention (trouble urinating) that may be caused by surgery, delivering a baby, or other conditions. Bethanechol may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Before taking this medicine You should not use bethanechol if you are allergic to it, or if you have: slow heartbeats or very low blood pressure (especially if this has caused you to faint); coronary artery disease (clogged arteries); asthma; an overactive thyroid; epilepsy or other seizure disorder; an active ulcer in your stomach or intestines; a blockage in your digestive tract (stomach or intestines); peritonitis (inflammation of the membrane lining the organs inside your abdomen); a bladder obstruction or other urination problems; Parkinson's disease; or if you recently had surgery on your bladder or intestines. Tell your doctor if you have ever had: urination problems, or a bladder infection; a stomach or intestinal disorder; heart problems; low blood pressure; a thyroid disorder; or breathing problems. Tell your doctor if you are pregnant. You should not breastfeed while using bethanechol. Bethanechol is not approved for use by anyone younger than 18 years old. How should I take bethanechol? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Take bethanechol on an empty stomach, at least 1 hour before or 2 hours after a meal. It may take up to 90 minutes before your symptoms improve. The effects of bethanechol usually last for about 1 hour. Call your doctor if your symptoms do not improve within 90 minutes after taking bethanechol. Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include drooling, stomach discomfort, nausea, vomiting, or feeling hot. What should I avoid while taking bethanechol? Avoid driving or hazardous activity until you know how bethanechol will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Bethanechol side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: slow heartbeats; a light-headed feeling, like you might pass out; or wheezing, chest tightness, trouble breathing. Common side effects may include: an urgent need to urinate; stomach cramps, nausea, diarrhea; burping, increased saliva; headache, dizziness; sweating, flushing (sudden warmth, redness, or tingly feeling); a general ill feeling; or watery eyes, vision changes. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Bethanechol dosing information Usual Adult Dose for Urinary Retention: Initial dose: 5 to 10 mg orally once to obtain minimum effective dose; repeat the same amount at hourly intervals until satisfactory response occurs or a maximum of 50 mg has been given Maintenance dose: 10 to 50 mg orally 3 to 4 times a day Comments: -Drug effects sometimes appear within 30 minutes and are usually maximal within 60 to 90 minutes. -Drug effects persist for about 1 hour. -If necessary, the effects of this drug can be eradicated promptly by atropine. Uses: For the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention; and for neurogenic atony of the urinary bladder with retention Usual Adult Dose for Neurogenic Bladder: Initial dose: 5 to 10 mg orally once to obtain minimum effective dose; repeat the same amount at hourly intervals until satisfactory response occurs or a maximum of 50 mg has been given Maintenance dose: 10 to 50 mg orally 3 to 4 times a day Comments: -Drug effects sometimes appear within 30 minutes and are usually maximal within 60 to 90 minutes. -Drug effects persist for about 1 hour. -If necessary, the effects of this drug can be eradicated promptly by atropine. Uses: For the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention; and for neurogenic atony of the urinary bladder with retention   What other drugs will affect bethanechol? Other drugs may affect bethanechol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is darifenacin? Darifenacin reduces muscle spasms of the bladder and urinary tract. Darifenacin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage). Darifenacin may also be used for purposes not listed in this medication guide. Warnings You should not take darifenacin if you are have untreated or uncontrolled narrow-angle glaucoma, a stomach disorder causing delayed emptying, or if you have trouble emptying your bladder. Before taking this medicine You should not take darifenacin if you are allergic to it, or if you have: untreated or uncontrolled narrow-angle glaucoma; a stomach disorder causing delayed emptying; or if you have trouble emptying your bladder. To make sure darifenacin is safe for you, tell your doctor if you have: glaucoma; liver disease; ulcerative colitis; a blockage in your stomach or intestines; a muscle disorder such as myasthenia gravis; or if you have very little urine or a weak stream of urine. FDA pregnancy category C. It is not known whether darifenacin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using darifenacin. It is not known whether darifenacin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. How should I take darifenacin? Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Take this medicine with water. Darifenacin can be taken with or without food. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause vision problems. What should I avoid while taking darifenacin? darifenacin may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Darifenacin side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using darifenacin and call your doctor at once if you have: severe stomach pain or constipation; confusion, hallucinations; little or no urinating; pain or burning when you urinate; or signs of dehydration--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin. Common side effects may include: nausea, indigestion; constipation; headache, dizziness; dry mouth; or blurred vision. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Darifenacin dosing information Usual Adult Dose for Urinary Incontinence: Initial dose: 7.5 mg orally once a day Maintenance dose: The dosage may be increased to 15 mg orally once a day as early as 2 weeks after starting therapy Comments: -This drug may be taken with or without food. -The tablet should be swallowed whole with water and not chewed, divided, or crushed. Use: For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency Usual Adult Dose for Urinary Frequency: Initial dose: 7.5 mg orally once a day Maintenance dose: The dosage may be increased to 15 mg orally once a day as early as 2 weeks after starting therapy Comments: -This drug may be taken with or without food. -The tablet should be swallowed whole with water and not chewed, divided, or crushed. Use: For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency   What other drugs will affect darifenacin? Tell your doctor about all medicines you use, and those you start or stop using during your treatment with darifenacin, especially: clarithromycin; flecainide; thioridazine; an antidepressant--amitriptyline, clomipramine, desipramine, doxepin, imipramine, nefazodone, nortriptyline; antifungal medicine--itraconazole, ketoconazole; or HIV or AIDS medicine--nelfinavir, ritonavir. This list is not complete. Other drugs may interact with darifenacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What is oxybutynin? Oxybutynin reduces muscle spasms of the bladder and urinary tract. Oxybutynin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased night-time urination. Oxybutynin is also used in children at least 6 years old with overactive bladder related to a neurologic condition such as spina bifida. Warnings You should not use oxybutynin if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate. Before using oxybutynin, tell your doctor if you have glaucoma, liver or kidney disease, an enlarged prostate, myasthenia gravis, ulcerative colitis, a blockage in your stomach or intestines, or a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion. Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease perspiration and you may be more prone to heat stroke. This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. There are many other medicines that can interact with oxybutynin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you. Stop using this medication and call your doctor if you have serious side effects such as hot and dry skin, extreme thirst, severe stomach pain or constipation, pain or burning when you urinate, or if you stop urinating. Before taking this medicine You should not use oxybutynin if you are allergic to it, or if you have: untreated or uncontrolled narrow-angle glaucoma; a blockage in your digestive tract (stomach or intestines); or if you are unable to urinate. To make sure you can safely take oxybutynin, tell your doctor if you have ever had: glaucoma; trouble urinating; ulcerative colitis; Parkinson's disease; dementia; a nerve disorder that affects your heart rate, blood pressure, or digestion; myasthenia gravis; or a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion. Tell your doctor if you are pregnant or breastfeeding. How should I take oxybutynin? Take oxybutynin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Take this medicine with a full glass of water, at the same time each day. You may take oxybutynin with or without food. Swallow the extended-release tablet whole and do not crush, chew, or break it. Measure liquid medicine with the supplied measuring device (not a kitchen spoon). Some tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using oxybutynin? Avoid driving or hazardous activity until you know how oxybutynin will affect you. Your reactions could be impaired. Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease sweating and you may be more prone to heat stroke. Drinking alcohol with this medicine can increase side effects. Oxybutynin side effects Get emergency medical help if you have signs of an allergic reaction to oxybutynin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have: severe stomach pain or constipation; blurred vision, tunnel vision, eye pain, or seeing halos around lights; little or no urination; painful or difficult urination; or dehydration - dizziness, confusion, feeling very thirsty, less urination or sweating. Common oxybutynin side effects may include: dizziness, drowsiness; headache; dry mouth; or diarrhea, constipation. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect oxybutynin? Using oxybutynin with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: antibiotic, antifungal, or antiviral medicine; bronchodilator asthma medication; cold or allergy medicine (Benadryl and others); medicine to treat overactive bladder; medicine to treat dementia; medicine to treat Parkinson's disease; or medicine to treat stomach problems, motion sickness, or irritable bowel syndrome. This list is not complete. Other drugs may interact with oxybutynin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.  

What is oxybutynin? Oxybutynin reduces muscle spasms of the bladder and urinary tract. Oxybutynin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased night-time urination. Oxybutynin is also used in children at least 6 years old with overactive bladder related to a neurologic condition such as spina bifida. Warnings You should not use oxybutynin if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate. Before using oxybutynin, tell your doctor if you have glaucoma, liver or kidney disease, an enlarged prostate, myasthenia gravis, ulcerative colitis, a blockage in your stomach or intestines, or a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion. Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease perspiration and you may be more prone to heat stroke. This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. There are many other medicines that can interact with oxybutynin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you. Stop using this medication and call your doctor if you have serious side effects such as hot and dry skin, extreme thirst, severe stomach pain or constipation, pain or burning when you urinate, or if you stop urinating. Before taking this medicine You should not use oxybutynin if you are allergic to it, or if you have: untreated or uncontrolled narrow-angle glaucoma; a blockage in your digestive tract (stomach or intestines); or if you are unable to urinate. To make sure you can safely take oxybutynin, tell your doctor if you have ever had: glaucoma; trouble urinating; ulcerative colitis; Parkinson's disease; dementia; a nerve disorder that affects your heart rate, blood pressure, or digestion; myasthenia gravis; or a stomach disorder such as gastroesophageal reflux disease (GERD) or slow digestion. Tell your doctor if you are pregnant or breastfeeding. How should I take oxybutynin? Take oxybutynin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Take this medicine with a full glass of water, at the same time each day. You may take oxybutynin with or without food. Swallow the extended-release tablet whole and do not crush, chew, or break it. Measure liquid medicine with the supplied measuring device (not a kitchen spoon). Some tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using oxybutynin? Avoid driving or hazardous activity until you know how oxybutynin will affect you. Your reactions could be impaired. Avoid becoming overheated or dehydrated during exercise and in hot weather. Oxybutynin can decrease sweating and you may be more prone to heat stroke. Drinking alcohol with this medicine can increase side effects. Oxybutynin side effects Get emergency medical help if you have signs of an allergic reaction to oxybutynin: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have: severe stomach pain or constipation; blurred vision, tunnel vision, eye pain, or seeing halos around lights; little or no urination; painful or difficult urination; or dehydration - dizziness, confusion, feeling very thirsty, less urination or sweating. Common oxybutynin side effects may include: dizziness, drowsiness; headache; dry mouth; or diarrhea, constipation. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect oxybutynin? Using oxybutynin with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: antibiotic, antifungal, or antiviral medicine; bronchodilator asthma medication; cold or allergy medicine (Benadryl and others); medicine to treat overactive bladder; medicine to treat dementia; medicine to treat Parkinson's disease; or medicine to treat stomach problems, motion sickness, or irritable bowel syndrome. This list is not complete. Other drugs may interact with oxybutynin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.  

What is tolterodine? Tolterodine is used in adults to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence (urine leakage). Tolterodine may also be used for purposes not listed in this medication guide. Warnings Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies. Before taking this medicine You should not use tolterodine if you are allergic to tolterodine or fesoterodine (Toviaz), or if you have: trouble emptying your bladder; a blockage in your stomach, slow digestion; or uncontrolled narrow-angle glaucoma. Tell your doctor if you have ever had: a stomach or intestinal disorder; problems with constipation; liver disease; kidney disease; myasthenia gravis; trouble emptying your bladder, or a weak stream of urine; glaucoma; or long QT syndrome (in you or a family member). Tell your doctor if you are pregnant or breastfeeding. How should I take tolterodine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take with water. Take tolterodine with or without food, at the same times each day. Swallow the capsule whole and do not crush, chew, break, or open it. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Skip the missed dose and use your next dose at the regular time. Do not use 2 doses in one day What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking tolterodine? Avoid driving or hazardous activity until you know how tolterodine will affect you. Your reactions could be impaired. Tolterodine side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using tolterodine and call your doctor at once if you have: confusion, hallucinations; severe stomach pain or constipation; or painful or difficult urination. Common side effects may include: dry mouth; dizziness; constipation; stomach pain; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Tolterodine dosing information Usual Adult Dose for Urinary Incontinence: Immediate release tablets: -Initial dose: 2 mg orally 2 times a day -Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability Extended release capsules: -Initial dose: 4 mg orally once a day -Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability Comments: -This drug can be taken with or without food. -The extended release formulation should be swallowed whole. Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency Usual Adult Dose for Urinary Frequency: Immediate release tablets: -Initial dose: 2 mg orally 2 times a day -Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability Extended release capsules: -Initial dose: 4 mg orally once a day -Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability Comments: -This drug can be taken with or without food. -The extended release formulation should be swallowed whole. Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency   What other drugs will affect tolterodine? Tolterodine can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Tell your doctor about all your other medicines, especially: cyclosporine; or vinblastine. This list is not complete. Other drugs may affect tolterodine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is tolterodine? Tolterodine is used in adults to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence (urine leakage). Tolterodine may also be used for purposes not listed in this medication guide. Warnings Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies. Before taking this medicine You should not use tolterodine if you are allergic to tolterodine or fesoterodine (Toviaz), or if you have: trouble emptying your bladder; a blockage in your stomach, slow digestion; or uncontrolled narrow-angle glaucoma. Tell your doctor if you have ever had: a stomach or intestinal disorder; problems with constipation; liver disease; kidney disease; myasthenia gravis; trouble emptying your bladder, or a weak stream of urine; glaucoma; or long QT syndrome (in you or a family member). Tell your doctor if you are pregnant or breastfeeding. How should I take tolterodine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take with water. Take tolterodine with or without food, at the same times each day. Swallow the capsule whole and do not crush, chew, break, or open it. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Skip the missed dose and use your next dose at the regular time. Do not use 2 doses in one day What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking tolterodine? Avoid driving or hazardous activity until you know how tolterodine will affect you. Your reactions could be impaired. Tolterodine side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using tolterodine and call your doctor at once if you have: confusion, hallucinations; severe stomach pain or constipation; or painful or difficult urination. Common side effects may include: dry mouth; dizziness; constipation; stomach pain; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Tolterodine dosing information Usual Adult Dose for Urinary Incontinence: Immediate release tablets: -Initial dose: 2 mg orally 2 times a day -Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability Extended release capsules: -Initial dose: 4 mg orally once a day -Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability Comments: -This drug can be taken with or without food. -The extended release formulation should be swallowed whole. Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency Usual Adult Dose for Urinary Frequency: Immediate release tablets: -Initial dose: 2 mg orally 2 times a day -Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability Extended release capsules: -Initial dose: 4 mg orally once a day -Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability Comments: -This drug can be taken with or without food. -The extended release formulation should be swallowed whole. Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency   What other drugs will affect tolterodine? Tolterodine can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Tell your doctor about all your other medicines, especially: cyclosporine; or vinblastine. This list is not complete. Other drugs may affect tolterodine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is trospium? Trospium relieves spasms of the bladder. Trospium is used to treat overactive bladder and symptoms of urinary incontinence, frequency, and urgency. Trospium may also be used for purposes not listed in this medication guide. Warnings You should not take trospium if you are allergic to trospium, or if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive system, or if you are unable to urinate. Take trospium on an empty stomach, at least 1 hour before a meal. Avoid drinking alcohol within 2 hours before or after you take trospium. Drinking alcohol can increase certain side effects of trospium. This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Avoid becoming overheated or dehydrated during exercise and in hot weather. Trospium can decrease sweating, which makes it easier for you to have heat stroke. Drink plenty of fluids while you are taking this medication. Before using trospium, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by trospium. Before taking this medicine You should not use trospium if you are allergic to it, or if you have: untreated or uncontrolled narrow-angle glaucoma; a blockage in your digestive system; or if you are unable to urinate. To make sure you can safely take trospium, tell your doctor if you have any of these other conditions: glaucoma; liver disease; kidney disease; a stomach or intestinal disorder such as ulcerative colitis; a muscle disorder such as myasthenia gravis; or an enlarged prostate. FDA pregnancy category C. It is not known whether trospium will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether trospium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medicine. How should I take trospium? Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Take trospium on an empty stomach, at least 1 hour before a meal. Extended-release trospium (Sanctura XR) should be taken once each morning, at least 1 hour before a meal. Do not crush, chew, break, or open an extended-release capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the missed dose 1 hour before your next meal. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe forms of some of the side effects listed in this medication guide. What should I avoid while taking trospium? This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Avoid drinking alcohol within 2 hours before or after you take trospium. Drinking alcohol can increase certain side effects of trospium. Avoid becoming overheated or dehydrated during exercise and in hot weather. Trospium can decrease sweating, which makes it easier for you to have heat stroke. Drink plenty of fluids while you are taking this medication. Trospium side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using trospium and call your doctor at once if you have a serious side effect such as: severe stomach pain or bloating; severe constipation; urinating less than usual or not at all; or confusion, hallucinations. Less serious side effects may include: dry mouth or throat; headache; mild constipation; upset stomach, gas; dizziness, drowsiness, or dry eyes. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Trospium dosing information Usual Adult Dose for Urinary Incontinence: Immediate-release formulation: 20 mg orally 2 times a day Extended-release formulation: 60 mg orally once a day in the morning Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency Usual Adult Dose for Urinary Frequency: Immediate-release formulation: 20 mg orally 2 times a day Extended-release formulation: 60 mg orally once a day in the morning Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency Usual Geriatric Dose for Urinary Incontinence: Immediate-release formulation: 75 years and older: 20 mg orally once a day based on tolerability Extended-release formulation: 60 mg orally once a day in the morning Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency Usual Geriatric Dose for Urinary Frequency: Immediate-release formulation: 75 years and older: 20 mg orally once a day based on tolerability Extended-release formulation: 60 mg orally once a day in the morning Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency   What other drugs will affect trospium? Before using trospium, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by trospium. Tell your doctor about all other medicines you use, especially: atropine (Atreza, Sal-Tropine, and others); belladonna (Donnatal, and others); benztropine (Cogentin); dimenhydrinate (Dramamine); metformin (Actoplus Met, Avandamet, Glucophage, Glucovance, Janumet, Kombiglyze, Metaglip, PrandiMet); morphine (Kadian, MS Contin, Oramorph); procainamide (Procanbid, Pronestyl); tenofovir (Viread); vancomycin (Vancocin); bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva); bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine); or ulcer medications such as glycopyrrolate (Robinul) or mepenzolate (Cantil). This list is not complete and other drugs may interact with trospium. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.