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Umbrella Health Care Systems - Medicines

Our pharmacy offers prescription drugs at discounted prices.

Aripiprazole tablet

Schizophrenia / Bipolar

What is aripiprazole? Aripiprazole is an antipsychotic medicine that is used to treat schizophrenia in adults and children at least 13 years old. Aripiprazole is also used in children 6 years or older who have Tourette's disorder, or symptoms of autistic disorder (irritability, aggression, mood swings, temper tantrums, and self-injury). Aripiprazole is used alone or with a mood stabilizer medicine to treat bipolar I disorder (manic depression) in adults and children at least 10 years old. Aripiprazole is used with antidepressant medication to treat major depressive disorder in adults. Warnings Aripiprazole is not approved for use in older adults with dementia-related psychosis. People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide. Do not stop using aripiprazole suddenly, or you could have unpleasant withdrawal symptoms. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how aripiprazole affects you. High blood sugar or diabetes, high cholesterol, and weight gain have happened with drugs like this one. These may raise the chance of heart and brain blood vessel disease. Low white blood cell counts have happened with drugs like this one. This may lead to a higher chance of infection. Rarely, infections have been deadly. Tell your doctor if you have ever had a low white blood cell count. Call your doctor right away if you have signs of infection like fever, chills, or sore throat. Before taking this medicine You should not take aripiprazole if you are allergic to it. Aripiprazole may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. To make sure aripiprazole is safe for you, tell your doctor if you have:: heart problems or a stroke; high or low blood pressure; diabetes (in you or a family member); seizures; or low white blood cell (WBC) counts. People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Stay alert to changes in your mood or symptoms. Your family or caregivers should also watch for sudden changes in your behavior. The liquid form (oral solution) of this medication contains sugar. Before taking aripiprazole oral solution, tell your doctor if you have diabetes. Aripiprazole can cause high blood sugar (hyperglycemia). If you are diabetic, check your blood sugar levels carefully. The orally disintegrating tablet form of this medication may contain over 3 milligrams of phenylalanine per tablet. Before taking Abilify Discmelt, tell your doctor if you have phenylketonuria (PKU). Taking antipsychotic medicine in the last 3 months of pregnancy may cause serious problems in the newborn. Tell your doctor right away if you get pregnant. Do not stop the medicine without your doctor's advice. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of aripiprazole on the baby. Ask a doctor if it is safe to breastfeed while using aripiprazole. How should I take aripiprazole? Take aripiprazole exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Aripiprazole can be taken with or without food. Swallow the regular tablet whole and do not crush, chew, or break it. Do not split the orally disintegrating tablet. Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).. Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves. If needed, you may drink liquid to help swallow the dissolved tablet. Your doctor will need to check your progress on a regular basis. If you also use antidepressant medicine, do not stop using it suddenly or you could have unpleasant symptoms. Ask your doctor before stopping the antidepressant. Store at room temperature away from moisture and heat. Aripiprazole liquid may be used for up to 6 months after opening, but not after the expiration date on the medicine label.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include drowsiness, vomiting, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma. What should I avoid while taking aripiprazole? Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid driving or hazardous activity until you know how aripiprazole will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid drinking alcohol. Dangerous side effects could occur. While taking aripiprazole, you may be more sensitive to very hot conditions. Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. Aripiprazole side effects Get emergency medical help if you have signs of an allergic reaction to aripiprazole: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Tell your doctor right away if you have new or sudden changes in mood or behavior, including new or worse depression or anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, more active or talkative, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: severe agitation, distress, or restless feeling; twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs; mask-like appearance of the face, trouble swallowing, problems with speech; seizure (convulsions); severe nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out; low blood cell counts - fever, chills, sore throat, weakness, easy bruising, unusual bleeding, purple or red spots under your skin; or high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor. You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs. Common aripiprazole side effects may include: blurred vision; increased saliva or drooling; muscle stiffness; uncontrolled muscle movements, shaking, anxiety, feeling restless; weight gain; nausea, vomiting, constipation; increased or decreased appetite; headache, dizziness, drowsiness, feeling tired; sleep problems (insomnia); or cold symptoms such as stuffy nose, sneezing, sore throat; This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect aripiprazole? Taking aripiprazole with other drugs that make you drowsy or slow your breathing can cause dangerous side effects or death. Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective. Many drugs can interact with aripiprazole. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all other medicines you use.

Olanzapine Tablet

Schizophrenia / Bipolar

What is olanzapine? Olanzapine is an antipsychotic medication that is used to treat psychotic conditions such as schizophrenia and bipolar disorder (manic depression) in adults and children at least 13 years old. Olanzapine is also used together with fluoxetine (Prozac) to treat episodes of depression in adults and children at least 10 years old who have bipolar I disorder. Olanzapine may also be used for purposes not listed in this medication guide. Warnings Olanzapine is not approved for use in older adults with dementia-related psychosis. Before taking this medicine You should not take olanzapine if you are allergic to it. Olanzapine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. Tell your doctor if you have ever had: liver disease; heart disease, high or low blood pressure; high cholesterol or triglycerides; a stroke, including "mini-stroke"; breast cancer; a seizure; Alzheimer's disease; diabetes or high blood sugar; an enlarged prostate; bowel problems; or narrow-angle glaucoma. Taking antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking olanzapine without your doctor's advice. Olanzapine can pass into breast milk. If you are breastfeeding, tell your doctor if you notice severe drowsiness, irritability, feeding problems, tremors, or unusual muscle movements in the nursing baby. The olanzapine orally disintegrating tablet (Zyprexa Zydis) may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU). How should I take olanzapine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Olanzapine can be taken with or without food. Remove an orally disintegrating tablet (Zyprexa Zydis) from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves. Olanzapine can cause high blood sugar (hyperglycemia). If you are diabetic, check your blood sugar levels on a regular basis. You may gain weight or have high cholesterol and triglycerides (types of fat) while taking olanzapine, especially if you are a teenager. You may need frequent blood tests. Call your doctor if your symptoms do not improve, or if they get worse while using olanzapine. Do not stop using olanzapine suddenly, even if you feel fine. Stopping suddenly may cause serious side effects. Olanzapine is sometimes used together with other antipsychotic medications or antidepressants. Use all medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor's advice. Medication may be only part of a complete program of treatment that also includes counseling and other psychological support programs. Follow your doctor's instructions. Store at room temperature away from moisture, heat, and light.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include drowsiness, agitation, aggression, slurred speech, confusion, increased heart rate, jerky or uncontrolled muscle movements, trouble breathing, or fainting. What should I avoid while taking olanzapine? Avoid driving or hazardous activity until you know how olanzapine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid drinking alcohol. Dangerous side effects could occur. Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking olanzapine. Olanzapine side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. High doses or long-term use of olanzapine can cause a serious movement disorder that may not be reversible. The longer you use olanzapine, the more likely you are to develop this disorder, especially if you are a woman or an older adult. Call your doctor at once if you have: uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); trouble speaking or swallowing; swelling in your hands or feet; confusion, unusual thoughts or behavior, hallucinations, or thoughts about hurting yourself; low white blood cell counts--fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing, feeling light-headed; or signs of dehydration--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; liver problems--upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); high blood sugar--increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss; or severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out. Common side effects may include: weight gain (more likely in teenagers), increased appetite; headache, dizziness, drowsiness, feeling tired or restless; problems with speech or memory; tremors or shaking, numbness or tingly feeling; changes in personality; dry mouth, or increased salivation; stomach pain, constipation; or pain in your arms or legs. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.  

Risperidone Tablet

Schizophrenia / Bipolar

What is risperidone? Risperidone is an antipsychotic medicine that works by changing the effects of chemicals in the brain. Risperidone is used to treat schizophrenia in adults and children who are at least 13 years old. Risperidone is also used to treat symptoms of bipolar disorder (manic depression) in adults and children who are at least 10 years old. Risperidone is also used to treat symptoms of irritability in autistic children who are 5 to 16 years old. Warnings Risperidone is not approved for use in older adults with dementia-related psychosis. Do not give risperidone to a child without a doctor's advice. While you are taking this medicine, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medication. Risperidone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of this medicine. Stop using this medicine and call your doctor at once if you have fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, restless muscle movements in your face or neck, tremor (uncontrolled shaking), trouble swallowing, feeling light-headed, or fainting. Before taking this medicine You should not use risperidone if you are allergic to it. Risperidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. To make sure this medicine is safe for you, tell your doctor if you have ever had: heart disease, high blood pressure, heart rhythm problems, stroke or heart attack; diabetes (or risk factors such as obesity or family history of diabetes); low white blood cell (WBC) counts; liver or kidney disease; seizures; breast cancer; low bone mineral density; trouble swallowing; Parkinson's disease; or if you are dehydrated. The risperidone orally disintegrating tablet may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU). Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking risperidone, do not stop taking it without your doctor's advice. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of risperidone on the baby. This medicine may temporarily affect fertility (ability to have children) in women. Risperidone can pass into breast milk and may cause side effects in the baby. If you breast-feed while using this medicine, tell your doctor if the baby has symptoms such as drowsiness, tremors, or involuntary muscle movements. Do not give this medicine to a child without a doctor's advice. How should I take risperidone? Take risperidone exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Risperidone can be taken with or without food. Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves. Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Do not mix the liquid medicine with cola or tea. It may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve. Store at room temperature away from moisture, heat, and light. Do not liquid medicine to freeze.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe drowsiness, fast heart rate, feeling light-headed, fainting, and restless muscle movements in your eyes, tongue, jaw, or neck. What to avoid Avoid driving or hazardous activity until you know how risperidone will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Dizziness or severe drowsiness can cause falls, fractures, or other injuries. Avoid drinking alcohol. Dangerous side effects could occur. While you are taking risperidone, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. Risperidone side effects Get emergency medical help if you have signs of an allergic reaction to risperidone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); breast swelling or tenderness (in men or women), nipple discharge, impotence, lack of interest in sex, missed menstrual periods; severe nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out; low white blood cells - sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing, skin sores, cold or flu symptoms, cough, trouble breathing; low levels of platelets in your blood - easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; or penis erection that is painful or lasts 4 hours or longer. Common risperidone side effects may include: headache; dizziness, drowsiness, feeling tired; tremors, twitching or uncontrollable muscle movements; agitation, anxiety, restless feeling; depressed mood; dry mouth, upset stomach, diarrhea, constipation; weight gain; or cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect risperidone? Taking risperidone with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: blood pressure medication; carbamazepine; clozapine; fluoxetine (Prozac) or paroxetine (Paxil); or levodopa. This list is not complete. Other drugs may interact with risperidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Ziprasidone capsule

Schizophrenia / Bipolar

What is ziprasidone? Ziprasidone is an antipsychotic medicine. Ziprasidone oral is used to treat schizophrenia and the manic symptoms of bipolar disorder (manic depression). Ziprasidone injection is used to quickly treat agitation in people with schizophrenia. Ziprasidone may also be used for purposes not listed in this medication guide. Warnings You should not use ziprasidone if you have a heart rhythm disorder, long QT syndrome, uncontrolled heart failure, or if you have recently had a heart attack. Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together. Stop taking ziprasidone and call your doctor right away if you have sudden dizziness, fast or pounding heartbeats, fluttering in your chest, shortness of breath, or a new or worsening skin rash with fever, or swollen glands. Ziprasidone is not approved for use in older adults with dementia-related psychosis. Before taking this medicine You should not use this medicine if you are allergic to ziprasidone, or if you have: a heart rhythm disorder; long QT syndrome (in you or a family member); uncontrolled or untreated heart failure; or if you have recently had a heart attack. Ziprasidone can cause a serious heart problem. Your risk may be higher if you also use certain other medicines. Your doctor may change your treatment plan if you also use: an antidepressant; bronchodilator asthma medication; cancer medicine; certain medicines for infections; heart or blood pressure medication; medicine to treat or prevent malaria; medicine to prevent nausea or vomiting; medicine to treat a psychiatric disorder; or medicine to treat HIV or AIDS. Ziprasidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. Tell your doctor if you have ever had: any heart problems; a heart attack or stroke; fainting spells; breast cancer; low blood levels of potassium or magnesium; diabetes (ziprasidone may raise your blood sugar); seizures or epilepsy; suicidal thoughts; Alzheimer's disease; trouble swallowing; liver disease; or kidney disease. Taking antipsychotic medicine in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking ziprasidone without your doctor's advice. You should not breastfeed while using this medicine. Older adults may be more sensitive to the effects of this medicine. Ziprasidone is not approved for use by anyone younger than 18 years old. How should I take ziprasidone? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Ziprasidone oral is taken by mouth. Ziprasidone injection is injected into a muscle. A healthcare provider will give you this injection if you are unable to take the medicine by mouth. Take ziprasidone with food. Swallow the capsule whole. You may need frequent medical tests. If you are diabetic, check your blood sugar levels on a regular basis while you are taking ziprasidone. It may take several weeks before your symptoms improve. Do not stop using ziprasidone suddenly, even if you feel fine. Keep using the medication as directed and tell your doctor if your symptoms do not improve. Store at room temperature away from moisture, light, and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking ziprasidone? While you are taking ziprasidone, you may be more sensitive to extreme temperatures, such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking ziprasidone. Avoid driving or hazardous activity until you know how ziprasidone will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid drinking alcohol. Dangerous side effects could occur. Ziprasidone side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Stop using ziprasidone and call your doctor at once if you have: fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out); uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); any skin rash, no matter how mild; low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough, trouble breathing; high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, agitation. Common side effects may include: dizziness, drowsiness, weakness; headache; nausea, vomiting; trouble swallowing; weight gain; feeling restless or being unable to sit still; tremors, involuntary muscle movements; vision problems; or runny nose, new or worsening cough. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Ziprasidone dosing information Usual Adult Dose for Schizophrenia: Oral: Initial dose: 20 mg orally twice a day Maintenance dose: Adjust as clinically indicated at intervals of not less than 2 days Maximum dose: 100 mg twice a day Comments: A dose greater than 80 mg twice a day is generally not recommended. Intramuscular: Recommended dose: 10 to 20 mg IM; may repeat 10 mg IM every 2 hours or 20 mg IM every 4 hours up to maximum daily dose Maximum dose: 40 mg IM per day Duration of therapy: Use beyond 3 consecutive days has not been studied Comments: -Coadministration of IM ziprasidone to patient's already taking oral ziprasidone has not been studied and is not recommended. -If long-term therapy is indicated, oral capsules should replace IM administration as soon as possible. Uses: -Treatment of schizophrenia (oral) -Acute treatment of agitation in schizophrenia (IM) Usual Adult Dose for Bipolar Disorder: Acute Treatment of Manic or Mixed Episodes: -Initial dose: 40 mg orally twice daily -Increase dose to 60 mg or 80 mg twice daily on the second day; subsequently adjust dose based on tolerance and efficacy within the dose range of 40 to 80 mg orally twice a day Maintenance Treatment (as adjunct to lithium or valproate): -Once stabilized, continue on same dose within the range of 40 to 80 mg orally twice daily. Comments: -The mean ziprasidone dose administered in flexible-dose clinical trials was approximately 120 mg per day. -Monotherapy has not been systematically evaluated for maintenance treatment of bipolar I disorder. Uses: -As monotherapy for the acute management of manic or mixed episodes associated with bipolar I disorder -As adjunct to lithium or valproate for the maintenance treatment of bipolar I disorder.   What other drugs will affect ziprasidone? Ziprasidone can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Using ziprasidone with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Many drugs can affect ziprasidone, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

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