Pharmacy

Categories By Alphabets

Umbrella Health Care Systems - Medicines

Our pharmacy offers prescription drugs at discounted prices.

Glyburide Tablet

Diabetes

What is glyburide? Glyburide is an oral diabetes medicine that helps control blood sugar levels. Glyburide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Glyburide is not for treating type 1 diabetes. Warnings You should not use glyburide if you are being treated with bosentan (Tracleer), or if you have diabetic ketoacidosis (call your doctor for treatment). Glyburide is not for treating type 1 diabetes. Before taking glyburide, tell your doctor if you are allergic to sulfa drugs, if you have been using insulin or chlorpropamide (Diabinese), or if you have hemolytic anemia (a lack of red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease. Take care not to let your blood sugar get too low. Low blood sugar (hypoglycemia) can occur if you skip a meal, exercise too long, drink alcohol, or are under stress. Symptoms include headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. Carry hard candy or glucose tablets with you in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your family and close friends know how to help you in an emergency. Before taking this medicine You should not use glyburide if you are allergic to it, or if: you are being treated with bosentan (Tracleer); you have type 1 diabetes; or you have diabetic ketoacidosis (call your doctor for treatment). Tell your doctor if you have ever had: hemolytic anemia (a lack of red blood cells); an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD); a nerve disorder affecting bodily functions; liver or kidney disease; or an allergy to sulfa drugs. Before taking glyburide, tell your doctor if you have taken another oral diabetes medicine or used insulin during the past 2 weeks. Glyburide may increase your risk of serious heart problems, but not treating your diabetes can also damage your heart and other organs. Talk to your doctor about the risks and benefits of this medicine. Tell your doctor if you are pregnant or breastfeeding. Follow your doctor's instructions about using glyburide if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby. How should I take glyburide? Glyburide is usually taken with breakfast or the first main meal of the day. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Your blood sugar may need to be checked often, and you may need other blood tests at your doctor's office. Low blood sugar (hypoglycemia) can happen to anyone who has diabetes. Symptoms include headache, hunger, sweating, irritability, dizziness, nausea, fast heart rate, and feeling anxious or shaky. To quickly treat low blood sugar, always keep a fast-acting source of sugar with you such as fruit juice, hard candy, crackers, raisins, or non-diet soda. Your doctor can prescribe a glucagon emergency injection kit to use in case you have severe hypoglycemia and cannot eat or drink. Be sure your family and close friends know how to give you this injection in an emergency. Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination. Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule. If your doctor changes your brand, strength, or type of glyburide, your dosage needs may change. Ask your pharmacist if you have any questions about the new kind of glyburide you receive at the pharmacy. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A glyburide overdose can cause life-threatening hypoglycemia. Symptoms of severe hypoglycemia include extreme weakness, nausea, tremors, sweating, confusion, trouble speaking, fast heartbeats, or seizure. What to avoid Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment. Glyburide could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Glyburide side effects Get emergency medical help if you have signs of an allergic reaction to glyburide (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). Call your doctor at once if you have: dark urine, jaundice (yellowing of the skin or eyes); severe skin rash, redness, or itching; pale skin, easy bruising or bleeding; fever, chills, sore throat, mouth sores; or low levels of sodium in the bodyheadache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady. Older adults may be more likely to have low blood sugar while taking glyburide. Common glyburide side effects may include: low blood sugar; nausea, heartburn, feeling full; muscle or joint pain; blurred vision; or mild rash or skin redness. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Dosing information Usual Adult Dose for Diabetes Type 2: Standard glyburide: -Initial dose: 2.5 mg to 5 mg orally once a day -Dose titration: Increase in increments of no more than 2.5 mg at weekly intervals based upon blood glucose response -Maintenance dose: 1.25 to 20 mg orally as a single dose or in divided doses -Maximum dose: 20 mg/day Micronized glyburide: -Initial dose: 1.5 mg to 3 mg orally once a day -Dose titration: Increase in increments of no more than 1.5 mg at weekly intervals based upon blood glucose response -Maintenance dose: 0.75 to 12 mg orally as a single dose or in divided doses -Maximum dose: 12 mg/day Comments: -Administer with breakfast or the first main meal of the day -Lower initial doses may be used in patients who are sensitive to hypoglycemic drugs -Once a day therapy is generally satisfactory, however, some patients may have a more satisfactory response with twice-a-day dosing, especially those receiving higher doses. TRANSFER FROM OTHER HYPOGLYCEMIC THERAPY: -Oral Antidiabetic Therapy: No exact dosage relationships exists between standard glyburide, micronized glyburide, or other oral hypoglycemic agents; when transferring patients from other oral hypoglycemic therapy, the maximum starting doses should be observed. -Insulin: --If the insulin dose is less than 20 units per day substitute 2.5 to 5 mg (standard) OR 1.5 to 3 mg (micronized) orally once a day. --If the insulin dose is between 20 and 40 units per day, substitute 5 mg (standard) OR 3 mg (micronized) orally once a day. --If the insulin dose is more than 40 units per day; transition the patient by concomitantly decreasing insulin by 50% and starting glyburide at 5 mg (standard) OR 3 mg (micronized) orally once a day; as insulin is progressively withdrawn, titrate in increments of 1.25 to 2.5 mg (standard) OR 0.75 to 1.5 mg (micronized) orally once a day every 2 to 10 days. Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Usual Geriatric Dose for Diabetes Type 2: Initial dose: 1.25 to 2.5 mg (standard) orally or 0.75 to 1.5 mg (micronized) orally once a day.   What other drugs will affect glyburide? If you also take colesevelam, take your glyburide dose 4 hours before you take colesevelam. Glyburide may not work as well when you use other medicines at the same time. Many other drugs can also affect blood sugar control. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Glyburide/Metformin Tablet

Diabetes

What is glyburide and metformin? Glyburide and metformin is a combination of two oral diabetes medicines that help control blood sugar levels. Glyburide and metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes. glyburide and metformin is not for treating type 1 diabetes. Glyburide and metformin may also be used for purposes not listed in this medication guide. Warnings You should not use this medicine if you have severe kidney disease, if you also take bosentan (Tracleer), or if you have metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment). If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking glyburide and metformin. You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired. Before taking this medicine You should not use glyburide and metformin if you are allergic to glyburide or metformin, or: severe kidney disease; metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment); or if you are also using bosentan (to treat pulmonary arterial hypertension). If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking glyburide and metformin. Tell your doctor if you have ever had: kidney disease; an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD); liver disease; or heart disease, heart attack, or stroke. You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk. Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby. However, you may need to stop taking glyburide and metformin for a short time just before your due date. Metformin may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk. You should not breastfeed while taking glyburide and metformin. How should I take glyburide and metformin? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Take glyburide and metformin with meals. Drink plenty of liquids while you are taking glyburide and metformin. Call your doctor if you are sick with vomiting, diarrhea, or a fever. These conditions can lead to severe dehydration, which could be dangerous while you are taking glyburide and metformin. You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda). Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency. Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination. Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule. Glyburide and metformin is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely. Your doctor may have you take extra vitamin B12 while you are taking glyburide and metformin. Take only the amount of vitamin B12 that your doctor has prescribed. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis. What should I avoid while taking glyburide and metformin? Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis. If you also take colesevelam, avoid taking it within 4 hours after you take glyburide and metformin. Glyburide and metformin side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: heart problems-- swelling, rapid weight gain, feeling short of breath; severe hypoglycemia--extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, seizure; or lactic acidosis--unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired. Common side effects may include: low blood sugar; nausea, diarrhea, upset stomach; or headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Glyburide / metformin side effects (more detail) Glyburide and metformin dosing information Usual Adult Dose for Diabetes Type 2: Doses provided as glyburide-metformin -As Initial Therapy in Patients with Inadequate Glycemic Control on Diet and Exercise Alone: Starting dose: 1.25 mg-250 mg orally once a day -Consider a starting dose of 1.25 mg-250 mg orally twice a day for patients with fasting blood glucose (FBG) greater than 200 mg/dL or HbA1c greater than 9% Maintenance Dose: Increase in increments of 1.25 mg-250 mg per day every 2 weeks up to the minimum effective dose to achieve glycemic control Maximum Initial Dose: 10 mg-2000 mg per day -Patients with Inadequate Glycemic Control on a Glyburide (or another Sulfonylurea) and/or Metformin: Initial dose: 2.5 mg-500 mg or 5 mg-500 mg orally twice a day Maintenance Dose: Increase in increments of no more than 5 mg-500 mg to the minimum effective dose to achieve adequate blood glucose control Maximum Dose: 20 mg-2000 mg per day Comments: -Give with meals; 5 mg-500 mg dose should not be used as initial therapy due to an increased risk of hypoglycemia; initial doses should be conservative to avoid hypoglycemia largely due to glyburide and gastrointestinal side effects largely due to metformin. -For patients who are switching to combination therapy, initial doses should not exceed the daily dose of glyburide (or equivalent sulfonylurea) and metformin already being taken; the decision to switch to the nearest equivalent dose should be based on clinical judgement. -Addition of thiazolidinedione may be appropriate for patients not adequately controlled on glyburide-metformin; in patients experiencing hypoglycemia, consider reducing the dose of the glyburide component. -Monitor patients closely for signs and symptoms of hypoglycemia. Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. Detailed Glyburide / metformin dosage information What other drugs will affect glyburide and metformin? Many drugs can affect glyburide and metformin, making glyburide and metformin less effective or increasing your risk of lactic acidosis. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Guanfacine ER tablet

ADHD

What is guanfacine? Guanfacine reduces nerve impulses in your heart and blood vessels. Guanfacine works by relaxing blood vessels, which lowers blood pressure and improves blood flow. The Tenex brand of guanfacine is used to treat high blood pressure (hypertension). It is sometimes given with other blood pressure medications. The Intuniv brand of guanfacine is used to treat attention deficit hyperactivity disorder (ADHD). Guanfacine may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Before taking this medicine You should not use guanfacine if you are allergic to it. Intuniv is not approved for use by anyone younger than 6 years old. Tenex is not approved for use by anyone younger than 12 years old. Tell your doctor if you have ever had: heart problems, coronary artery disease (clogged arteries); a heart rhythm disorder; a heart attack or stroke; high or low blood pressure; liver disease; or kidney disease. It is not known whether guanfacine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks. How should I take guanfacine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Take Intuniv with a full glass of water, milk, or other liquid. Take Tenex at bedtime to ease drowsiness. Swallow the Intuniv tablet whole and do not crush, chew, or break it. If a child is using this medicine, tell your doctor if the child has any changes in weight. Intuniv doses are based on weight in children, and any changes may affect your child's dose. You should not stop using guanfacine suddenly. Stopping suddenly can raise your blood pressure and cause unpleasant symptoms. Call your doctor if you are sick with vomiting and cannot take your medicine as usual. Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using only the form and strength your doctor prescribes. Your doctor will need to check your progress on a regular basis. Your blood pressure and heart rate may also need to be checked. If you have high blood pressure, keep using Tenex even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Avoid taking guanfacine with high-fat foods, or your body could absorb the medicine too quickly. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Call your doctor for instructions if you miss more than 2 doses in a row. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe drowsiness, slow heart rate, and feeling like you might pass out. What should I avoid while taking guanfacine? Avoid driving or hazardous activity until you know how guanfacine will affect you. Your reactions could be impaired. Drinking alcohol can increase certain side effects of guanfacine. Guanfacine side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: anxiety, nervousness; hallucinations (especially in children); severe drowsiness; slow heartbeats; or a light-headed feeling, like you might pass out; If you stop taking guanfacine, tell your doctor if you have headaches, confusion, rapid heartbeats, tremors, increased blood pressure, or if you feel nervous or agitated. If left untreated, these symptoms could lead to very high blood pressure, vision problems, or seizures. Common side effects may include: dizziness, drowsiness; low blood pressure, slow heartbeats; feeling tired or irritable; trouble sleeping; dry mouth; or stomach pain, nausea, constipation. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Guanfacine dosing information Usual Adult Dose for Hypertension: Initial dose: 1 mg orally once a day at bedtime; may increase to 2 mg once a day if satisfactory result not achieved after 3 to 4 weeks. Comments: Adverse reactions increase significantly with doses above 3 mg/day. Usual Pediatric Dose for Attention Deficit Disorder: 6 YEARS TO LESS THAN 18 YEARS: Initial dose: 1 mg orally once a day, either in the morning or evening, at approximately the same time each day; may adjust in increments of no more than 1 mg/week. Recommended target dose: 0.05 to 0.12 mg/kg/day (total daily dose between 1 and 7 mg) once a day, depending on clinical response and tolerability Maximum dose: 6 to 12 years: Doses above 4 mg/day have not been evaluated; 13 to 17 years: Doses above 7 mg/day have not been evaluated. Comments: Attention Deficit Hyperactivity Disorder (ADHD) may require treatment for an extended period of time; healthcare providers should periodically reevaluate treatment and adjust dose as needed. Use: Treatment of ADHD as monotherapy and as adjunctive therapy to stimulant medications. Usual Pediatric Dose for Hypertension: 12 YEARS OR OLDER: Initial dose: 1 mg orally once a day at bedtime; may increase to 2 mg once a day if satisfactory result not achieved after 3 to 4 weeks. Comments: Adverse reactions increase significantly with doses above 3 mg/day.   What other drugs will affect guanfacine? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Using guanfacine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety, depression, or seizures. Tell your doctor about all your other medicines. Some may affect guanfacine, especially: ketoconazole; a barbiturate, such as phenobarbital; blood pressure medications; medicine to treat mental illness; or a sedative, such as Valium or Xanax. This list is not complete. Other drugs may affect guanfacine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Halobetasol Prop Ointment 0.05%

Psoriasis

What is halobetasol topical? Halobetasol is a highly potency corticosteroid medicine that helps reduce inflammation in the body. Halobetasol topical (for the skin) is used to treat inflammation and itching caused by plaque psoriasis or other inflamed and itchy skin conditions that respond to corticosteroid medication. Halobetasol topical is available as a cream, ointment, lotion, or foam. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Before taking this medicine You should not use halobetasol if you are allergic to it. To make sure halobetasol is safe for you, tell your doctor if you have ever had: any type of skin infection; a skin reaction to any steroid medicine; an adrenal gland disorder; liver disease; or if you plan to have surgery. Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes. It is not known whether halobetasol topical will harm an unborn baby. Tell your doctor if you are pregnant. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply halobetasol to your chest, avoid areas that may come into contact with the baby's mouth. Halobetasol topical is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over. Children can absorb larger amounts of halobetasol through the skin and may be more likely to have side effects. How should I use halobetasol topical? Use halobetasol exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Do not take by mouth. Topical medicine is for use only on the skin. Do not use on open wounds or on sunburned, windburned, dry, or irritated skin. Rinse with water if halobetasol gets in your eyes or mouth. Wash your hands before and after using halobetasol, unless you are using this medicine to treat the skin on your hands. Shake the foam before each use. Apply a thin layer of halobetasol topical to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to. Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects. If you are treating the diaper area, do not use plastic pants or tight-fitting diapers. Halobetasol is for short-term use only (2 weeks, or up to 8 weeks for psoriasis). Follow your doctor's dosing instructions very carefully. If you use halobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled. You may need medical tests to be sure halobetasol is not causing harmful effects. Call your doctor if your symptoms do not improve, or if they get worse. You should not stop using halobetasol suddenly. Follow your doctor's instructions about tapering your dose. Store at room temperature away from moisture and heat. Do not freeze. Keep halobetasol topical foam away from open flame or high heat. The canister may explode if it gets too hot. Do not puncture or burn an empty canister. Dosing information Usual Adult Dose for Dermatitis: Apply a thin layer to affected area once or twice a day Usual Adult Dose for Eczema: Apply a thin layer to affected area once or twice a day Usual Adult Dose for Psoriasis: Apply a thin layer to affected area once or twice a day Usual Pediatric Dose for Dermatitis: 12 years or older: Apply a thin layer to affected area once or twice a day Usual Pediatric Dose for Eczema: 12 years or older: Apply a thin layer to affected area once or twice a day Usual Pediatric Dose for Psoriasis: 12 years or older: Apply a thin layer to affected area once or twice a day Comments: -Treatment should be limited to two weeks. -Use should be limited to 50 g a week. -Use should be discontinued when control is achieved. -Reassessment of diagnosis may be needed, if no improvement is seen in two weeks. -This topical drug should not be used with occlusive dressings. Use: Relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses   What happens if I miss a dose? Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. High doses or long-term use of halobetasol topical can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid while using halobetasol topical? Avoid applying halobetasol topical to your face, scalp, underarms, or groin area. Do not use halobetasol topical to treat any skin condition that has not been checked by your doctor. Avoid using other topical steroid medications on the areas you treat with halobetasol unless your doctor tells you to. Halobetasol topical side effects Get emergency medical help if you have signs of an allergic reaction to halobetasol: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: worsening of your skin condition; redness, warmth, swelling, oozing, or severe irritation of any treated skin; blurred vision, tunnel vision, eye pain, or seeing halos around lights; high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; or possible signs of absorbing this medicine through your skin - weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes. Common halobetasol side effects may include: burning, stinging, itching, or dryness of treated skin; pain where the foam was applied; redness or crusting around your hair follicles; stretch marks; spider veins; headache; or cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect halobetasol topical? Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Haloperidol Tablet

Psychosis

What is haloperidol? Haloperidol is an antipsychotic medicine that is used to treat schizophrenia. Haloperidol is also used to control motor and speech tics in people with Tourette's syndrome. Haloperidol may also be used for purposes not listed in this medication guide. Warnings Haloperidol is not approved for use in older adults with dementia-related psychosis. Before taking this medicine You should not use haloperidol if you are allergic to it, or if you have: Parkinson's disease; or certain conditions that affect your central nervous system (such as severe drowsiness, or slowed thinking caused by taking other medicines or drinking alcohol). Haloperidol may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. Tell your doctor if you have ever had: heart problems, angina (chest pain); long QT syndrome (in you or a family member); low blood pressure; a seizure; a thyroid disorder; breast cancer; or an electrolyte imbalance (such as low blood levels of potassium or magnesium). Using antipsychotic medicine in the last 3 months of pregnancy may cause serious problems in the newborn. If you get pregnant, tell your doctor right away. Do not stop the medicine without your doctor's advice. Ask a doctor if it is safe to breastfeed while using haloperidol. How should I take haloperidol? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Taking too much haloperidol can cause a serious heart rhythm disorder or sudden death. Never take more than your prescribed dose. Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon). Your symptoms may not improve for several weeks. You may have withdrawal symptoms if you stop using haloperidol suddenly. Ask your doctor before stopping the medicine. Store at room temperature away from moisture, heat, and light. Do not allow liquid medicine to freeze.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of haloperidol can be fatal. What should I avoid while taking haloperidol? Drinking alcohol with haloperidol can cause side effects. Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Dizziness or severe drowsiness can cause falls, fractures, or other injuries. Haloperidol side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. High doses or long-term use of haloperidol can cause a serious movement disorder that may not be reversible. The longer you use haloperidol, the more likely you are to develop this disorder, especially if you are a woman or an older adult. Call your doctor at once if you have: uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); muscle spasms in your neck, tightness in your throat, trouble swallowing; rapid changes in mood or behavior; fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out); cough with mucus, chest pain, feeling short of breath; low white blood cell counts--fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing; or severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out. Common side effects may include: drowsiness; headache; dizziness, spinning sensation; uncontrolled muscle movements; feeling restless or anxious; sleep problems (insomnia); or breast enlargement, irregular menstrual periods. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect haloperidol? Haloperidol can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Using haloperidol with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: lithium; rifampin; medicine to treat Parkinson's disease; seizure medicine; or a blood thinner--warfarin, Coumadin, Jantoven. This list is not complete. Other drugs may affect haloperidol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Hydralazine Tablet

Blood Pressure / Heart

What is hydralazine? Hydralazine is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries. Hydralazine is used to treat high blood pressure (hypertension). Hydralazine may also be used for purposes not listed in this medication guide. Warnings You should not use hydralazine if you have coronary artery disease, or rheumatic heart disease affecting the mitral valve. Before taking this medicine You should not use hydralazine if you are allergic to it, or if you have: coronary artery disease; or rheumatic heart disease affecting the mitral valve. To make sure hydralazine is safe for you, tell your doctor if you have ever had: kidney disease; systemic lupus erythematosus; angina (chest pain); or a stroke. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Hydralazine can pass into breast milk, but effects on the nursing baby are not known. Tell your doctor if you are breast-feeding. Hydralazine is not approved for use by anyone younger than 18 years old. How should I take hydralazine? Follow all directions on your prescription label. Do not take hydralazine in larger or smaller amounts or for longer than recommended. Your blood pressure will need to be checked often. You may also need frequent blood tests. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include rapid heartbeats, warmth or tingling under your skin, chest pain, or fainting. What should I avoid while taking hydralazine? Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Hydralazine side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: chest pain or pressure, pain spreading to your jaw or shoulder; fast or pounding heartbeats; a light-headed feeling, like you might pass out; numbness, tingling, or burning pain in your hands or feet; painful or difficult urination; little or no urination; or lupus-like syndrome--joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behavior, and patchy skin color. Common side effects may include: chest pain, fast heart rate; headache; or nausea, vomiting, diarrhea, loss of appetite. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect hydralazine? Tell your doctor about all your current medicines and any you start or stop using, especially: diazoxide (an injectable blood pressure medication); or an MAO inhibitor--isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. This list is not complete. Other drugs may interact with hydralazine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Hydrochlorothiazide Capsule

Blood Pressure / Fluid Retention

What is HCTZ? HCTZ (hydrochlorothiazide) is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. HCTZ is used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. HCTZ is also used to treat high blood pressure (hypertension). Warnings You should not use HCTZ if you are allergic to hydrochlorothiazide or if you are unable to urinate. Before using HCTZ, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin. Avoid drinking alcohol, which can increase some of the side effects of HCTZ. Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. There are many other drugs that can interact with HCTZ. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you. If you are being treated for high blood pressure, keep using HCTZ even if you feel fine. High blood pressure often has no symptoms. Before taking this medicine You should not use HCTZ if you are allergic to hydrochlorothiazide, or if you are unable to urinate. To make sure HCTZ is safe for you, tell your doctor if you have ever had: kidney disease; liver disease; gout; glaucoma; low levels of potassium or sodium in your blood; high levels of calcium in your blood; a parathyroid gland disorder; diabetes; or an allergy to sulfa drugs or penicillin. Tell your doctor if you are pregnant or plan to become pregnant. If you take HCTZ during pregnancy, your newborn baby may develop jaundice or other problems. You should not breastfeed while using HCTZ. HCTZ is not approved for use by anyone younger than 18 years old. How should I take HCTZ? Take HCTZ exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking HCTZ, which can lead to severely low blood pressure or a serious electrolyte imbalance. Your blood pressure will need to be checked often. Your blood and urine may be tested if you have been vomiting or are dehydrated. If you need surgery, tell your surgeon you currently use HCTZ. You may need to stop for a short time. Keep using HCTZ as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store HCTZ at room temperature away from moisture, heat, and freezing. Keep the bottle tightly closed when not in use. HCTZ dosing information Usual Adult Dose of HCTZ for Edema: Usual dose: 25 mg to 100 mg orally once or twice daily Comments: -Some patients respond to intermittent therapy, (i.e., administration on alternate days or on 3 to 5 days each week). Excessive response and undesirable electrolyte imbalance are less likely to occur with intermittent dosing. Usual Adult Dose of HCTZ for Hypertension: Initial dose: 25 mg orally once daily Maintenance dose: May increase to 50 mg orally daily, as a single or 2 divided doses Comments: -Patients usually do not require doses in excess of 50 mg daily when used concomitantly with other antihypertensive agents. Usual Adult Dose of HCTZ for Nephrocalcinosis: Initial: 25 mg orally once daily Maintenance dose: May increase to 50 mg twice daily Usual Adult Dose Dose of HCTZ for Osteoporosis: Initial: 25 mg orally once daily Maintenance dose: May increase to 50 mg daily Usual Adult Dose Dose of HCTZ for Diabetes Insipidus: Initial: 50 mg orally once daily Maintenance dose: May increase to 100 mg orally daily Usual PediatricDose of HCTZ Dose for Edema: Less than 6 months: Up to 3 mg/kg/day (up to 1.5 mg/pound) orally in 2 divided doses Less than 2 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 37.5 mg per day 2 to 12 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 100 mg per day Usual Pediatric Dose Dose of HCTZ for Hypertension: Less than 6 months: Up to 3 mg/kg/day (up to 1.5 mg/pound) orally in 2 divided doses Less than 2 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 37.5 mg per day 2 to 12 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 100 mg per day   What happens if I miss a dose? Take HCTZ as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, dizziness, dry mouth, thirst, and muscle pain or weakness. What should I avoid while taking HCTZ? HCTZ may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis. Drinking alcohol with HCTZ can cause side effects. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. HCTZ side effects Get emergency medical help if you have signs of an allergic reaction to hydrochlorothiazide (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Call your doctor at once if you have: a light-headed feeling; eye pain, vision problems; jaundice (yellowing of the skin or eyes); pale skin, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum); shortness of breath, wheezing, cough with foamy mucus, chest pain; dehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or signs of an electrolyte imbalance - increased thirst or urination, confusion, vomiting, constipation, muscle pain, leg cramps, bone pain, lack of energy, irregular heartbeats, tingly feeling. Common hydrochlorothiazide side effects may include: weakness; feeling like you might pass out; severe pain in your upper stomach spreading to your back, nausea and vomiting; fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or electrolyte imbalance. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect HCTZ? Taking HCTZ with other drugs that make you light-headed can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: cholestyramine, colestipol; insulin or oral diabetes medicine; lithium; other blood pressure medications; steroid medicine; or NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect hydrochlorothiazide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Hydrochlorothiazide Tablet

Blood Pressure / Fluid Retention

What is HCTZ? HCTZ (hydrochlorothiazide) is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. HCTZ is used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. HCTZ is also used to treat high blood pressure (hypertension). Warnings You should not use HCTZ if you are allergic to hydrochlorothiazide or if you are unable to urinate. Before using HCTZ, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin. Avoid drinking alcohol, which can increase some of the side effects of HCTZ. Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. There are many other drugs that can interact with HCTZ. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you. If you are being treated for high blood pressure, keep using HCTZ even if you feel fine. High blood pressure often has no symptoms. Before taking this medicine You should not use HCTZ if you are allergic to hydrochlorothiazide, or if you are unable to urinate. To make sure HCTZ is safe for you, tell your doctor if you have ever had: kidney disease; liver disease; gout; glaucoma; low levels of potassium or sodium in your blood; high levels of calcium in your blood; a parathyroid gland disorder; diabetes; or an allergy to sulfa drugs or penicillin. Tell your doctor if you are pregnant or plan to become pregnant. If you take HCTZ during pregnancy, your newborn baby may develop jaundice or other problems. You should not breastfeed while using HCTZ. HCTZ is not approved for use by anyone younger than 18 years old. How should I take HCTZ? Take HCTZ exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking HCTZ, which can lead to severely low blood pressure or a serious electrolyte imbalance. Your blood pressure will need to be checked often. Your blood and urine may be tested if you have been vomiting or are dehydrated. If you need surgery, tell your surgeon you currently use HCTZ. You may need to stop for a short time. Keep using HCTZ as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store HCTZ at room temperature away from moisture, heat, and freezing. Keep the bottle tightly closed when not in use. HCTZ dosing information Usual Adult Dose of HCTZ for Edema: Usual dose: 25 mg to 100 mg orally once or twice daily Comments: -Some patients respond to intermittent therapy, (i.e., administration on alternate days or on 3 to 5 days each week). Excessive response and undesirable electrolyte imbalance are less likely to occur with intermittent dosing. Usual Adult Dose of HCTZ for Hypertension: Initial dose: 25 mg orally once daily Maintenance dose: May increase to 50 mg orally daily, as a single or 2 divided doses Comments: -Patients usually do not require doses in excess of 50 mg daily when used concomitantly with other antihypertensive agents. Usual Adult Dose of HCTZ for Nephrocalcinosis: Initial: 25 mg orally once daily Maintenance dose: May increase to 50 mg twice daily Usual Adult Dose Dose of HCTZ for Osteoporosis: Initial: 25 mg orally once daily Maintenance dose: May increase to 50 mg daily Usual Adult Dose Dose of HCTZ for Diabetes Insipidus: Initial: 50 mg orally once daily Maintenance dose: May increase to 100 mg orally daily Usual PediatricDose of HCTZ Dose for Edema: Less than 6 months: Up to 3 mg/kg/day (up to 1.5 mg/pound) orally in 2 divided doses Less than 2 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 37.5 mg per day 2 to 12 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 100 mg per day Usual Pediatric Dose Dose of HCTZ for Hypertension: Less than 6 months: Up to 3 mg/kg/day (up to 1.5 mg/pound) orally in 2 divided doses Less than 2 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 37.5 mg per day 2 to 12 years: 1 to 2 mg/kg/day (0.5 to 1 mg/pound) orally daily as a single dose or in 2 divided doses Maximum dose 100 mg per day   What happens if I miss a dose? Take HCTZ as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, dizziness, dry mouth, thirst, and muscle pain or weakness. What should I avoid while taking HCTZ? HCTZ may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis. Drinking alcohol with HCTZ can cause side effects. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. HCTZ side effects Get emergency medical help if you have signs of an allergic reaction to hydrochlorothiazide (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Call your doctor at once if you have: a light-headed feeling; eye pain, vision problems; jaundice (yellowing of the skin or eyes); pale skin, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum); shortness of breath, wheezing, cough with foamy mucus, chest pain; dehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or signs of an electrolyte imbalance - increased thirst or urination, confusion, vomiting, constipation, muscle pain, leg cramps, bone pain, lack of energy, irregular heartbeats, tingly feeling. Common hydrochlorothiazide side effects may include: weakness; feeling like you might pass out; severe pain in your upper stomach spreading to your back, nausea and vomiting; fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or electrolyte imbalance. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect HCTZ? Taking HCTZ with other drugs that make you light-headed can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: cholestyramine, colestipol; insulin or oral diabetes medicine; lithium; other blood pressure medications; steroid medicine; or NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect hydrochlorothiazide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Hydrocortisone tablet

Allergies / Arthritis / Hormones / Asthma

What is hydrocortisone topical? Hydrocortisone topical (for the skin) is a steroid that is used to treat inflammation and itching caused by skin conditions that respond to steroid medication. There are many brands and forms of hydrocortisone topical available. Not all brands are listed on this leaflet. Hydrocortisone topical may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Before taking this medicine You should not use hydrocortisone topical if you are allergic to it. Tell your doctor if you have ever had: any type of skin infection; a skin reaction to any steroid medicine; liver disease; or an adrenal gland disorder. Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes. Do not give hydrocortisone topical to a child younger than 2 years old without medical advice. Ask a doctor before using this medicine if you are pregnant or breastfeeding. If you apply hydrocortisone topical to your chest, avoid areas that may come into contact with the baby's mouth. How should I use hydrocortisone topical? Use exactly as directed on the label, or as prescribed by your doctor. Do not take by mouth. Topical medicine is for use only on the skin. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Wash your hands before and after using hydrocortisone, unless you are using this medicine to treat the skin on your hands. Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to. Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects. Shake hydrocortisone lotion and spay well just before each use. If you are treating the diaper area, do not use plastic pants or tight-fitting diapers. Stop using hydrocortisone and call your doctor if your symptoms do not improve, or if they get worse within 7 days. Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.   What happens if I miss a dose? Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. High doses or long-term use of hydrocortisone topical can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid while using hydrocortisone topical? Do not use hydrocortisone topical to treat any skin condition that has not been checked by your doctor. Do not get hydrocortisone topical in your eyes. If contact does occur, rinse with water. Hydrocortisone topical side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: worsening of your skin condition; redness, warmth, swelling, oozing, or severe irritation of any treated skin; high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes. Less serious side effects may be more likely, and you may have none at all. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect hydrocortisone topical? Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Hydroxychloroquine tablet

Arthritis / Malaria

What is hydroxychloroquine? Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine is not effective against all strains of malaria, or against malaria in areas where the infection has been resistant to a similar drug called chloroquine. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Warnings Hydroxychloroquine can cause dangerous effects on your heart, especially if you also use certain other medicines including the antibiotic azithromycin (Z-Pak). Seek emergency medical attention if you have fast or pounding heartbeats and sudden dizziness (like you might pass out). Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye that could progress to permanent vision problems. Stop taking hydroxychloroquine and call your doctor at once if you have blurred vision, trouble focusing, distorted vision, blind spots, trouble reading, changes in your color vision, increased sensitivity to light. Before taking this medicine You should not use hydroxychloroquine if you are allergic to hydroxychloroquine or chloroquine. High doses or long-term use of hydroxychloroquine may cause irreversible damage to your retina (the membrane layer inside your eye that helps produce vision). This could progress to permanent vision problems. The risk of retinal damage is higher in people with pre-existing eye problems, kidney disease, or people who also take tamoxifen. To make sure hydroxychloroquine is safe for you, tell your doctor if you have ever had: vision changes or damage to your retina caused by an anti-malaria medication; heart disease, heart rhythm disorder (such as long QT syndrome); diabetes; a stomach disorder; an allergy to quinine; liver or kidney disease; psoriasis; alcoholism; porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system); or a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency. Tell your doctor if you are pregnant or plan to become pregnant. Malaria is more likely to cause serious illness or death in a pregnant woman. Having malaria during pregnancy may also increase the risk of miscarriage, stillbirth, premature delivery, and low birth weight. It is not known whether hydroxychloroquine will harm an unborn baby. If you are pregnant, ask your doctor about the risks of traveling to areas where malaria is common (such as Africa, South America, and Southern Asia). It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Hydroxychloroquine is not approved for treating lupus or rheumatoid arthritis in anyone younger than 18 years old. How should I take hydroxychloroquine? Take hydroxychloroquine exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Take hydroxychloroquine with a meal or a glass of milk unless your doctor tells you otherwise. To treat lupus or arthritis, hydroxychloroquine is usually taken daily. To prevent malaria: Hydroxychloroquine is usually taken once per week on the same day each week. Start taking the medicine 2 weeks before entering an area where malaria is common. Keep taking the medicine during your stay and for at least 4 weeks after you leave the area. To treat malaria: Hydroxychloroquine is usually given as one high dose followed by smaller doses during the next 2 days in a row. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Call your doctor as soon as possible if you have been exposed to malaria, or if you have fever or other symptoms of illness during or after a stay in an area where malaria is common. Use protective clothing, insect repellents, and mosquito netting around your bed to further prevent mosquito bites that could cause malaria. No medication is 100% effective in treating or preventing all types of malaria. Talk with your doctor if you have fever, vomiting, or diarrhea during your treatment. While using hydroxychloroquine, you may need frequent medical tests and vision exams. Store at room temperature away from moisture, heat, and light. Dosing information Usual Adult Dose for Malaria Prophylaxis: 400 mg salt (310 mg base) orally once a week Weight-based dosing: 6.5 mg/kg salt (5 mg/kg base) orally once a week -Maximum dose: 400 mg salt (310 mg base)/dose Comments: -This drug should be administered on the same day of each week. -Suppressive therapy should begin 2 weeks prior to exposure and should continue for 4 weeks after leaving the endemic area. Use: For the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported US CDC Recommendations: 310 mg base (400 mg salt) orally once a week Comments: -An alternative to chloroquine for prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas -If malaria develops while using this drug for chemoprophylaxis, it should not be used as part of the treatment regimen. -Current guidelines should be consulted for additional information. Usual Adult Dose for Malaria: 800 mg salt (620 mg base) orally as an initial dose, followed by 400 mg salt (310 mg base) at 6, 24, and 48 hours after the initial dose Total dose: 2000 mg salt (1550 mg base) Weight-based dosing: -First dose: 13 mg/kg salt (10 mg/kg base) orally -Second dose (6 hours after first dose): 6.5 mg/kg salt (5 mg/kg base) orally -Third dose (24 hours after first dose): 6.5 mg/kg salt (5 mg/kg base) orally -Fourth dose (48 hours after first dose): 6.5 mg/kg salt (5 mg/kg base) orally Maximum Dose: -First dose: 800 mg salt (620 mg base)/dose -Second, third, and fourth dose: 400 mg salt (310 mg base)/dose Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of Plasmodium vivax and P ovale infections. Use: For the treatment of uncomplicated malaria due to P falciparum, P malariae, P ovale, and P vivax US CDC Recommendations: 620 mg base (800 mg salt) orally at once, followed by 310 mg base (400 mg salt) orally at 6, 24, and 48 hours Total dose: 1550 mg base (2000 mg salt) Comments: -Recommended for uncomplicated malaria (P falciparum or species not identified) in regions with chloroquine sensitivity -Recommended for uncomplicated malaria (P malariae, P knowlesi, P vivax [unless chloroquine-resistant P vivax suspected], or P ovale) in all regions; if treating P vivax or P ovale infections, concomitant treatment with primaquine (after quantitative testing to rule out glucose-6-phosphate dehydrogenase [G6PD] deficiency) is recommended. -Recommended for uncomplicated malaria treatment for pregnant women in regions with chloroquine sensitivity -Current guidelines should be consulted for additional information. Usual Adult Dose for Systemic Lupus Erythematosus: 200 to 400 mg salt (155 to 310 mg base)/day orally divided in 1 or 2 doses Comments: -Doses above 400 mg/day are not recommended. -Higher incidence of retinopathy reported when this maintenance dose is exceeded. Uses: For the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus Usual Adult Dose for Rheumatoid Arthritis: Initial dose: 400 to 600 mg salt (310 to 465 mg base)/day orally divided in 1 or 2 doses Maintenance dose: 200 to 400 mg salt (155 to 310 mg base)/day orally divided in 1 or 2 doses Maximum dose: 600 mg salt (465 mg base)/day or 6.5 mg/kg salt (5 mg/kg base)/day, whichever is lower Comments: -The action of this drug is cumulative and may require weeks to months to achieve the maximum therapeutic effect. -When a good response is obtained, the initial dose may be reduced by 50% and continued at a maintenance dose. -Higher incidence of retinopathy reported when this maintenance dose is exceeded; 600 mg salt (465 mg base) or 6.5 mg/kg salt (5 mg/kg base), whichever is lower, should not be exceed per day. -Corticosteroids and salicylates may be used with this drug, and they can generally be decreased gradually in dosage or eliminated after a maintenance dose of this drug has been achieved. Use: For the treatment of acute and chronic rheumatoid arthritis Usual Pediatric Dose for Malaria Prophylaxis: 6.5 mg/kg salt (5 mg/kg base) orally once a week Maximum dose: 400 mg salt (310 mg base)/dose Comments: -This drug should be administered on the same day of each week. -Suppressive therapy should begin 2 weeks prior to exposure and should continue for 4 weeks after leaving the endemic area. Use: For the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported US CDC Recommendations: 5 mg/kg base (6.5 mg/kg salt) orally once a week Maximum dose: 310 mg base (400 mg salt)/dose Comments: -An alternative to chloroquine for prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas -If malaria develops while using this drug for chemoprophylaxis, it should not be used as part of the treatment regimen. -Current guidelines should be consulted for additional information. Usual Pediatric Dose for Malaria: First dose: 13 mg/kg salt (10 mg/kg base) orally Second dose (6 hours after first dose): 6.5 mg/kg salt (5 mg/kg base) orally Third dose (24 hours after first dose): 6.5 mg/kg salt (5 mg/kg base) orally Fourth dose (48 hours after first dose): 6.5 mg/kg salt (5 mg/kg base) orally Maximum Dose: -First dose: 800 mg salt (620 mg base)/dose -Second, third, and fourth dose: 400 mg salt (310 mg base)/dose Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of P vivax and P ovale infections. Use: For the treatment of uncomplicated malaria due to P falciparum, P malariae, P ovale, and P vivax US CDC Recommendations: 10 mg/kg base orally at once, followed by 5 mg/kg base orally at 6, 24, and 48 hours Total dose: 25 mg/kg base Comments: -Pediatric dose should never exceed adult dose. -Recommended for uncomplicated malaria (P falciparum or species not identified) in regions with chloroquine sensitivity -Recommended for uncomplicated malaria (P malariae, P knowlesi, P vivax [unless chloroquine-resistant P vivax suspected], or P ovale) in all regions; if treating P vivax or P ovale infections, concomitant treatment with primaquine (after quantitative testing to rule out G6PD deficiency) is recommended. -Current guidelines should be consulted for additional information.   What happens if I miss a dose? Call your doctor for instructions if you miss a dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of hydroxychloroquine can be fatal, and must be treated quickly. Overdose symptoms may include drowsiness, vision changes, seizure, slow heart rate, weak pulse, pounding heartbeats, sudden dizziness, fainting, shortness of breath, or slow breathing (breathing may stop). Keep hydroxychloroquine out of the reach of children. A hydroxychloroquine overdose can be fatal to a child who accidentally swallows this medicine. What to avoid This medicine may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you. Avoid taking an antacid or Kaopectate (kaolin-pectin) within 4 hours before or 4 hours after you take hydroxychloroquine. Hydroxychloroquine side effects Get emergency medical help if you have signs of an allergic reaction to hydroxychloroquine (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Also seek emergency medical attention if you have symptoms of a serious heart problem: fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out). Call your doctor at once if you have: a seizure; yellowing of your eyes; ringing in your ears, trouble hearing; unusual mood changes; severe muscle weakness, loss of coordination, underactive reflexes; low blood cell counts - fever, chills, tiredness, sore throat, mouth sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; low blood sugar - headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or a serious drug reaction that can affect many parts of your body - skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and tell your doctor if you have: blurred vision, trouble focusing, trouble reading; distorted vision, blind spots; changes in your color vision; hazy or cloudy vision; seeing light flashes or streaks, seeing halos around lights; or increased sensitivity to light. Common hydroxychloroquine side effects may include: headache, dizziness; nausea, vomiting, stomach pain; loss of appetite, weight loss; feeling nervous or irritable; skin rash or itching; or hair loss. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.  

Hydroxyurea capsule

Cancer / Sickle Cell / Psoriasis

What is hydroxyurea? Hydroxyurea is used to treat chronic myeloid leukemia, ovarian cancer, and certain types of skin cancer (squamous cell cancer of the head and neck). Hydroxyurea is also used to reduce pain episodes and the need for blood transfusions in people with sickle cell anemia. Hydroxyurea will not cure sickle cell anemia. Hydroxyurea may also be used for purposes not listed in this medication guide. Warnings Both men and women using hydroxyurea should use birth control to prevent pregnancy. The use of hydroxyurea by either parent may cause birth defects. Using hydroxyurea may increase your risk of developing other types of cancer, such as leukemia or skin cancer. Wear protective clothing and use sunscreen when you are outdoors. Hydroxyurea can weaken your immune system. Call your doctor at once if you have a fever, chills, body aches, extreme tiredness, shortness of breath, bruising, or unusual bleeding. Before taking this medicine You should not use hydroxyurea if you are allergic to it. Tell your doctor if you have ever had: kidney disease (or if you are on dialysis); liver disease; a wound or ulcer on your leg; HIV or AIDS (especially if you take antiviral medicine); high levels of uric acid in your blood; or treatment with an interferon, chemotherapy, or radiation. Using hydroxyurea may increase your risk of developing other types cancer or leukemia. Talk with your doctor about your specific risk. Hydroxyurea can harm an unborn baby. Both men and women using this medicine should use birth control to prevent pregnancy. The use of this medicine by either parent may cause birth defects. If you are a woman, keep using birth control for at least 6 months after your last dose of hydroxyurea. If you are a man, keep using birth control for at least 1 year after your last dose (6 months if you took Siklos). Tell your doctor right away if a pregnancy occurs while either the mother or the father is using this medicine. This medicine may affect fertility (ability to have children) in men. However, it is important to use birth control because hydroxyurea may harm the baby if a pregnancy does occur. You should not breastfeed while you are taking hydroxyurea. Older adults may be more sensitive to the effects of this medicine. How should I take hydroxyurea? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Hydroxyurea is usually taken once per day at the same time of day, with or without food. Swallow the pill whole with a glass of water. Wash your hands before and after you handle hydroxyurea or the bottle that contains the pills. For best protection, wear disposable gloves when handling the pills. Do not open the hydroxyurea capsule or crush or chew a tablet. Do not use a broken pill. The medicine from a crushed or broken pill can be dangerous if it gets in your eyes, mouth, or nose, or on your skin. If this occurs, wash your skin with soap and water or rinse your eyes with water. If any powder from a broken pill is spilled, wipe it up at once with a damp paper towel and throw the towel away in a sealed plastic bag where children and pets cannot get to it. Your doctor may also want you to take a folic acid supplement. Follow dosing instructions very carefully. Hydroxyurea can lower your blood cell counts. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using hydroxyurea. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include drowsiness, mouth sores, and swelling with pain and purple discoloration in your hands and feet. What should I avoid while taking hydroxyurea? Using hydroxyurea may increase your risk of developing skin cancer. Avoid exposure to sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Do not receive a "live" vaccine while using hydroxyurea, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine. Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection. Do not handle hydroxyurea pills or the medicine bottle without skin protection (disposable gloves). Hydroxyurea side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: numbness, tingling, or burning pain in your hands or feet; skin numbness or purple discoloration; skin ulcers or open sores; sudden chest pain, wheezing, dry cough, feeling short of breath; low blood cell counts--fever, chills, tiredness, mouth sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed; or signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes). Common side effects may include: loss of appetite, nausea; constipation, diarrhea; low blood cell counts; bleeding; or mouth sores. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect hydroxyurea? Some medicines can increase your risk of serious side effects while taking hydroxyurea. Tell your doctor if you are also using antiviral medicine or an interferon. Other drugs may affect hydroxyurea, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Hydroxyzine HCL Tablet

Allergies / Anxiety / Itching

What is hydroxyzine? Hydroxyzine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of itching, or hives on the skin. Hydroxyzine may be used to treat allergic skin reactions such as hives or contact dermatitis. Since hydroxyzine also reduces activity in the central nervous system, it can be used as a sedative to treat anxiety and tension. It is also used together with other medications given during and after general anesthesia. Hydroxyzine is also used to treat allergic skin reactions such as hives or contact dermatitis. Warnings Hydroxyzine may cause birth defects. Talk to you doctor before using hydroxyzine if pregnant or breastfeeding. Hydroxyzine can cause a serious heart problem, especially if you use certain medicines at the same time. Tell your doctor about all your current medicines and any you start or stop using. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Stop using this medicine and call your doctor at once if you have a serious side effect such as tremors, confusion, seizures, or restless muscle movements in your eyes, tongue, jaw, or neck. Drinking alcohol can increase certain side effects of hydroxyzine. Before taking this medicine You should not use hydroxyzine if you are allergic to it, or if: you have long QT syndrome; you are allergic to cetirizine (Zyrtec) or levocetirizine (Xyzal); or Hydroxyzine could harm the unborn baby or cause birth defects. Talk to you doctor before using hydroxyzine if pregnant. To make sure this medicine is safe for you, tell your doctor if you have: blockage in your digestive tract (stomach or intestines); bladder obstruction or other urination problems; glaucoma; heart disease, slow heartbeats; personal or family history of long QT syndrome; an electrolyte imbalance (such as high or low levels of potassium in your blood); if you have recently had a heart attack. It is not known whether hydroxyzine passes into breast milk or if it could harm a nursing baby. Talk to your doctor before breastfeeding while using this medicine. Do not give this medicine to a child without medical advice. How should I take hydroxyzine? Take hydroxyzine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended. Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. Hydroxyzine is for short-term use only. You should not take this medicine for longer than 4 months. Call your doctor if your anxiety symptoms do not improve, or if they get worse. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe drowsiness, nausea, vomiting, uncontrolled muscle movements, or seizure (convulsions). What to avoid This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol with this medicine can cause side effects. Hydroxyzine side effects Get emergency medical help if you have signs of an allergic reaction to hydroxyzine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. In rare cases, hydroxyzine may cause a severe skin reaction. Stop taking this medicine and call your doctor right away if you have sudden skin redness or a rash that spreads and causes white or yellow pustules, blistering, or peeling. Stop using hydroxyzine and call your doctor at once if you have: fast or pounding heartbeats; headache with chest pain; severe dizziness, fainting; or a seizure (convulsions). Side effects such as drowsiness and confusion may be more likely in older adults. Common hydroxyzine side effects may include: drowsiness; headache; dry mouth; or skin rash. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect hydroxyzine? Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking hydroxyzine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. Hydroxyzine can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with this medicine. Other drugs may interact with hydroxyzine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Hydroxyzine Pamoate Capsule

Allergies / Anxiety / Itching

What is hydroxyzine? Hydroxyzine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of itching, or hives on the skin. Hydroxyzine may be used to treat allergic skin reactions such as hives or contact dermatitis. Since hydroxyzine also reduces activity in the central nervous system, it can be used as a sedative to treat anxiety and tension. It is also used together with other medications given during and after general anesthesia. Hydroxyzine is also used to treat allergic skin reactions such as hives or contact dermatitis. Warnings Hydroxyzine may cause birth defects. Talk to you doctor before using hydroxyzine if pregnant or breastfeeding. Hydroxyzine can cause a serious heart problem, especially if you use certain medicines at the same time. Tell your doctor about all your current medicines and any you start or stop using. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Stop using this medicine and call your doctor at once if you have a serious side effect such as tremors, confusion, seizures, or restless muscle movements in your eyes, tongue, jaw, or neck. Drinking alcohol can increase certain side effects of hydroxyzine. Before taking this medicine You should not use hydroxyzine if you are allergic to it, or if: you have long QT syndrome; you are allergic to cetirizine (Zyrtec) or levocetirizine (Xyzal); or Hydroxyzine could harm the unborn baby or cause birth defects. Talk to you doctor before using hydroxyzine if pregnant. To make sure this medicine is safe for you, tell your doctor if you have: blockage in your digestive tract (stomach or intestines); bladder obstruction or other urination problems; glaucoma; heart disease, slow heartbeats; personal or family history of long QT syndrome; an electrolyte imbalance (such as high or low levels of potassium in your blood); if you have recently had a heart attack. It is not known whether hydroxyzine passes into breast milk or if it could harm a nursing baby. Talk to your doctor before breastfeeding while using this medicine. Do not give this medicine to a child without medical advice. How should I take hydroxyzine? Take hydroxyzine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended. Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. Hydroxyzine is for short-term use only. You should not take this medicine for longer than 4 months. Call your doctor if your anxiety symptoms do not improve, or if they get worse. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe drowsiness, nausea, vomiting, uncontrolled muscle movements, or seizure (convulsions). What to avoid This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol with this medicine can cause side effects. Hydroxyzine side effects Get emergency medical help if you have signs of an allergic reaction to hydroxyzine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. In rare cases, hydroxyzine may cause a severe skin reaction. Stop taking this medicine and call your doctor right away if you have sudden skin redness or a rash that spreads and causes white or yellow pustules, blistering, or peeling. Stop using hydroxyzine and call your doctor at once if you have: fast or pounding heartbeats; headache with chest pain; severe dizziness, fainting; or a seizure (convulsions). Side effects such as drowsiness and confusion may be more likely in older adults. Common hydroxyzine side effects may include: drowsiness; headache; dry mouth; or skin rash. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect hydroxyzine? Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking hydroxyzine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures. Hydroxyzine can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with this medicine. Other drugs may interact with hydroxyzine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Ibuprofen Tablet

Arthritis

What is ibuprofen? Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Ibuprofen is used to reduce fever and treat pain or inflammation caused by many conditions such as headache, toothache, back pain, arthritis, menstrual cramps, or minor injury. Ibuprofen is used in adults and children who are at least 6 months old. Warnings Ibuprofen can increase your risk of fatal heart attack or stroke. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults. Do not take more than your recommended dose. An ibuprofen overdose can damage your stomach or intestines. Use only the smallest amount of medication needed to get relief from your pain, swelling, or fever. Before taking this medicine You should not use ibuprofen if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. Ask a doctor or pharmacist if this medicine is safe to use if you have ever had: heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke; a heart attack, stroke, or blood clot; stomach ulcers or bleeding; liver or kidney disease; asthma; or if you take aspirin to prevent heart attack or stroke. Ask a doctor before using this medicine if you are pregnant or breastfeeding. If you are pregnant, you should not take ibuprofen unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. Do not give ibuprofen to a child younger than 6 months old without the advice of a doctor. How should I take ibuprofen? Use ibuprofen exactly as directed on the label, or as prescribed by your doctor. Use the lowest dose that is effective in treating your condition. An ibuprofen overdose can damage your stomach or intestines. The maximum amount of ibuprofen for adults is 800 milligrams per dose or 3200 mg per day (4 maximum doses). A child's dose is based on the age and weight of the child. Carefully follow the dosing instructions provided with children's ibuprofen for the age and weight of your child. Ask a doctor or pharmacist if you have questions. Take ibuprofen with food or milk to lessen stomach upset. Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). You must chew the chewable tablet before you swallow it. Store at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.   What happens if I miss a dose? Since ibuprofen is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, stomach pain, drowsiness, black or bloody stools, coughing up blood, shallow breathing, fainting, or coma. What to avoid Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to ibuprofen (such as aspirin, ketoprofen, or naproxen). Avoid taking aspirin unless your doctor tells you to. If you also take aspirin to prevent stroke or heart attack, taking ibuprofen can make aspirin less effective in protecting your heart and blood vessels. If you take both medicines, take ibuprofen at least 8 hours before or 30 minutes after you take aspirin (non-enteric coated form). Avoid drinking alcohol. It may increase your risk of stomach bleeding. Ibuprofen side effects Get emergency medical help if you have signs of an allergic reaction to ibuprofen (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath. Stop using this medicine and call your doctor at once if you have: changes in your vision; shortness of breath (even with mild exertion); swelling or rapid weight gain; a skin rash, no matter how mild; signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; liver problems - nausea, upper stomach pain, itching, tired feeling, flu-like symptoms, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); low red blood cells (anemia) - pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or kidney problems - little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath. Common ibuprofen side effects may include: nausea, vomiting, gas; bleeding; or dizziness, headache. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect ibuprofen? Ask your doctor before using ibuprofen if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily. Ask a doctor or pharmacist before using ibuprofen with any other medications, especially: cyclosporine; lithium; methotrexate; a blood thinner (warfarin, Coumadin, Jantoven); heart or blood pressure medication, including a diuretic or "water pill"; or steroid medicine (such as prednisone). This list is not complete. Other drugs may interact with ibuprofen, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Imatinib tablet

Cancer

What is imatinib? Imatinib interferes with the growth of some cancer cells. Imatinib is used to treat certain types of leukemia (blood cancer), bone marrow disorders, and skin cancer. Imatinib is also used to treat certain tumors of the stomach and digestive system. Warnings Imatinib can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches). Imatinib may increase the risk of liver problems. Tell your doctor if you have upper stomach pain, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). Imatinib may increase the risk of fluid retention or heart problems. Tell your doctor if you have swelling or rapid weight gain, shortness of breath, fast or slow heart rate, weak pulse, or fainting. Before taking this medicine You should not use imatinib if you are allergic to it. To make sure imatinib is safe for you, tell your doctor if you have ever had: liver disease (especially hepatitis B); kidney disease; underactive thyroid, recent or upcoming thyroid surgery; heart disease, high blood pressure, congestive heart failure; a stomach ulcer or bleeding; diabetes; or chemotherapy. You may need to have a negative pregnancy test before starting this treatment. Do not use imatinib if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using imatinib and for at least 14 days after your last dose. Do not breast-feed a baby while you are using this medicine and for at least 1 month after your last dose. How should I take imatinib? Take imatinib exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Take imatinib with a meal and a large glass of water. Do not take imatinib on an empty stomach. If you cannot swallow a tablet whole, you may dissolve it in a glass of water or apple juice to make the pill easier to swallow. Use about 2 ounces of liquid for each 100-milligram tablet, or 7 ounces of liquid for each 400-milligram tablet. Stir the mixture and drink all of it right away. Do not use a broken tablet. The medicine from a broken pill can be dangerous if it gets in your mouth, eyes, or nose, or on your skin. If this happens, wash your skin with soap and water or rinse your eyes with water. Ask your pharmacist how to safely dispose of a broken pill. Imatinib can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. You will also need frequent tests to check your liver function. Do not stop using imatinib without your doctor's advice. Store at room temperature away from moisture and heat. Dosing information Usual Adult Dose of Imatinib for Chronic Myelogenous Leukemia: Chronic phase: 400 mg orally once a day Accelerated phase or blast crisis: 600 mg orally once a day A dose increase may be considered in the absence of a severe adverse drug reaction and severe non-leukemia related neutropenia or thrombocytopenia in the following circumstances: disease progression (at any time), failure to achieve a satisfactory hematologic response after at least 3 months of treatment, failure to achieve a cytogenetic response after 6 to 12 months of treatment, or loss of a previously achieved hematologic or cytogenetic response: -Disease progression chronic phase: 600 mg orally once a day -Disease progression accelerated phase or blast crisis: 400 mg orally 2 times a day Uses: -Newly diagnosed patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+CML) in chronic phase -Patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+CML) in blast crisis (BC), accelerated phase (AP), or in chronic phase (CP) after failure of interferon-alpha therapy Usual Adult Dose of Imatinib for Acute Lymphoblastic Leukemia: 600 mg orally daily Use: For relapsed or refractory Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) Usual Adult Dose of Imatinib for Myeloproliferative Disorder: 400 mg orally once a day Comments: -Determine PDGFRb gene rearrangements status prior to initiating therapy. Use: For patients with myelodysplastic/myeloproliferative (MDS/MPD) diseases associated with PDGFR (platelet-derived growth factor receptor) gene rearrangements Usual Adult Dose of Imatinib for Myelodysplastic Disease: 400 mg orally once a day Comments: -Determine PDGFRb gene rearrangements status prior to initiating therapy. Use: For patients with myelodysplastic/myeloproliferative (MDS/MPD) diseases associated with PDGFR (platelet-derived growth factor receptor) gene rearrangements Usual Adult Dose of Imatinib for Systemic Mastocytosis: -For patients with ASM without the D816V c-Kit mutation: 400 mg orally daily -If c-Kit mutational status is not known or unavailable: 400 mg orally daily may be considered for patients with ASM not responding satisfactorily to other therapies. -For patients with ASM associated with eosinophilia, a clonal hematological disease related to the fusion kinase FIP1L1-PDGFR alpha, a starting dose of 100 mg/day is recommended. Dose increase from 100 mg to 400 mg for these patients may be considered in the absence of adverse drug reactions if assessments demonstrate an insufficient response to therapy. -For patients with ASM associated with eosinophilia (a clonal hematological disease related to the fusion kinase FIP1L1-PDGFR alpha: 100 mg orally daily; a dose increase from 100 mg to 400 mg for these patients may be considered in the absence of adverse drug reactions if assessments demonstrate an insufficient response to therapy Comments: -Determine D816V c-Kit mutation status prior to initiating treatment. Use: For patients with aggressive systemic mastocytosis without the D816V c-Kit mutation Usual Adult Dose of Imatinib for Hypereosinophilic Syndrome: -For patients with HES/CEL: 400 mg orally daily -For patients with HES/CEL with demonstrated FIP1L1-PDGFR alpha fusion kinase: 100 mg orally daily; dose increase from 100 mg to 400 mg for these patients may be considered in the absence of adverse drug reactions if assessments demonstrate an insufficient response to therapy Use: For patients with hypereosinophilic syndrome and/or chronic eosinophilic leukemia who have the FIP1L1-PDGFR alpha fusion kinase (mutational analysis or FISH demonstration of CHIC2 allele deletion) and for patients with HES and/or CEL who are FIP1L1-PDGFR alpha fusion kinase negative or unknown Usual Adult Dose of Imatinib for Chronic Eosinophilic Leukemia: -For patients with HES/CEL: 400 mg orally daily -For patients with HES/CEL with demonstrated FIP1L1-PDGFR alpha fusion kinase: 100 mg orally daily; dose increase from 100 mg to 400 mg for these patients may be considered in the absence of adverse drug reactions if assessments demonstrate an insufficient response to therapy Use: For patients with hypereosinophilic syndrome and/or chronic eosinophilic leukemia who have the FIP1L1-PDGFR alpha fusion kinase (mutational analysis or FISH demonstration of CHIC2 allele deletion) and for patients with HES and/or CEL who are FIP1L1-PDGFR alpha fusion kinase negative or unknown Usual Adult Dose of Imatinib for Dermatofibrosarcoma Protuberans: 100 mg orally daily Use: For patients with unresectable, recurrent and/or metastatic dermatofibrosarcoma protuberans (DFSP) Usual Pediatric Dose of Imatinib for Chronic Myelogenous Leukemia: 1 year and older: 340 mg/m2 orally once a day or 170 mg/m2 orally 2 times a day Maximum Dose: 600 mg daily Comments: -Therapy can be given as a once daily dose or the daily dose may be split into 2 doses, with one portion dosed in the morning and one portion in the evening. -There is no experience with this drug in children under 1 year of age. Use: -Newly diagnosed patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+CML) in chronic phase.   What happens if I miss a dose? Take your dose as soon as you can, making sure you also eat a meal and drink a large glass of water. Skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking imatinib? imatinib may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls, accidents, or severe injuries. Grapefruit may interact with imatinib and lead to unwanted side effects. Avoid the use of grapefruit products. Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection. Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth. Imatinib side effects Get emergency medical help if you have signs of an allergic reaction to imatinib (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). Call your doctor at once if you have: fluid retention - shortness of breath (even while lying down), swelling, rapid weight gain; kidney problems - little or no urination, swelling in your feet or ankles; fluid build-up in the lungs - pain when you breathe, wheezing, gasping for breath, cough with foamy mucus; liver problems - upper stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes); low blood cell counts - fever, cold or flu symptoms, easy bruising, unusual bleeding, mouth sores, pale skin, unusual tiredness, feeling light-headed, cold hands and feet; signs of stomach bleeding - bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; signs of tumor cell breakdown - confusion, weakness, muscle cramps, nausea, vomiting, fast or slow heart rate, decreased urination, tingling in your hands and feet or around your mouth; or thyroid symptoms - tiredness, dry skin, hair loss, constipation, depression, slow heart rate, weight gain, feeling more sensitive to cold temperatures. Imatinib can affect growth in children and teenagers. Tell your doctor if your child is not growing at a normal rate while using this medicine. Common imatinib side effects may include: fluid retention; nausea, vomiting, stomach pain, diarrhea; joint or muscle pain; skin rash; or feeling tired. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect imatinib? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Tell your doctor about all your current medicines. Many drugs can interact with imatinib, especially: an antibiotic, antifungal, or antiviral medicine; seizure medicine; a blood thinner such as warfarin (Coumadin, Jantoven); or a vitamin or mineral supplement that contains iron. This list is not complete and many other drugs may affect imatinib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Indapamide Tablet

Blood Pressure / Fluid Retention

What is indapamide? Indapamide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Indapamide treats fluid retention (edema) in people with congestive heart failure. indapamide is also used to treat high blood pressure (hypertension). Indapamide may also be used for purposes not listed in this medication guide. Warnings You should not use this medicine if you are allergic to sulfa drugs or if you are unable to urinate. Before taking this medicine You should not use indapamide if you are allergic to it, or if: you are unable to urinate; or you are allergic to sulfa drugs. To make sure indapamide is safe for you, tell your doctor if you have: cirrhosis or other liver disease; kidney disease; low levels of potassium or sodium in your blood; gout; diabetes; lupus; or if you are on a low-salt diet. Indapamide is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether indapamide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using indapamide. Indapamide is not approved for use by anyone younger than 18 years old. How should I take indapamide? Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended. Indapamide is usually taken once per day in the morning. Follow your doctor's dosing instructions very carefully. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine, which can lead to severely low blood pressure or a serious electrolyte imbalance. While using indapamide, you may need frequent medical tests and blood pressure checks. Your blood and urine may both be tested if you have been vomiting or are dehydrated. If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include vomiting, weakness, dizziness, dry mouth, thirst, and muscle pain or weakness. What should I avoid while taking indapamide? Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. Indapamide side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have signs of an electrolyte imbalance, such as: drowsiness, lack of energy, feeling tired; leg cramps, muscle weakness or limp feeling; severe weakness, loss of coordination, feeling unsteady; fast or irregular heartbeats, fluttering in your chest, feeling restless; numbness or tingling; vomiting, constipation; headache, confusion, slurred speech; a light-headed feeling, like you might pass out; dry mouth, increased thirst; or little or no urinating. Common side effects may include: dizziness; weakness, tiredness; back pain, muscle cramps; feeling anxious or agitated; headache; or runny nose. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Indapamide dosing information Usual Adult Dose for Edema: Initial dose: 2.5 mg orally once a day. Usual Adult Dose for Hypertension: Initial dose: 1.25 mg orally once a day.   What other drugs will affect indapamide? Tell your doctor about all your current medicines and any you start or stop using, especially: digoxin, digitalis; lithium; blood pressure medication; or steroids (prednisone and others). This list is not complete. Other drugs may interact with indapamide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Indomethacin capsule

Pain / Inflammation

What is indomethacin? Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID). Indomethacin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, gouty arthritis, or ankylosing spondylitis. Indomethacin is also used to treat shoulder pain caused by bursitis or tendinitis. Extended-release indomethacin (Indocin SR) should not be used to treat gouty arthritis. Indomethacin may also be used for purposes not listed in this medication guide. Warnings Indomethacin can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use indomethacin just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Indomethacin may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using indomethacin, especially in older adults. Before taking this medicine Indomethacin can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Indomethacin may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using indomethacin, especially in older adults. You should not use indomethacin if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. Tell your doctor if you have ever had: heart disease, high blood pressure; a heart attack, stroke, or blood clot; fluid retention; bleeding problems; stomach ulcers or bleeding; asthma; liver or kidney disease; or if you smoke. If you are pregnant, you should not take indomethacin unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. This medicine may temporarily affect fertility (ability to have children) in women. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Indomethacin is not approved for use by anyone younger than 14 years old. How should I take indomethacin? Follow all directions on your prescription label and read all medication guides. Use the lowest dose that is effective in treating your condition. Swallow the extended-release capsule whole and do not crush, chew, break, or open it. Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Your dose needs may change if you switch to a different brand, strength, or form of indomethacin. Avoid medication errors by using only the form and strength your doctor prescribes. If you use this medicine long-term, you may need frequent medical tests. If you need surgery, tell your surgeon you currently use this medicine. You may need to stop for a short time. Store at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe drowsiness, stomach pain, or vomiting. What should I avoid while taking indomethacin? Avoid alcohol. Heavy drinking can increase your risk of stomach bleeding. Avoid taking aspirin unless your doctor tells you to. Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to indomethacin (such as aspirin, ibuprofen, ketoprofen, or naproxen). Indomethacin side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath. Stop using indomethacin and call your doctor at once if you have: a skin rash, no matter how mild; changes in your vision; heart problems--swelling, rapid weight gain, feeling short of breath; signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea, vomiting, diarrhea, unusual tiredness, itching, flu-like symptoms, dark urine, jaundice (yellowing of the skin or eyes); signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet. Common side effects may include: indigestion, nausea; headache; or dizziness. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect indomethacin? Ask your doctor before using indomethacin if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily. Ask a doctor or pharmacist before using indomethacin with any other medications, especially: cyclosporine; lithium; methotrexate; probenecid; heart or blood pressure medication, including a diuretic or "water pill"; a blood thinner--warfarin, Coumadin, Jantoven; or other NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, meloxicam, and others. This list is not complete. Other drugs may affect indomethacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Indomethacin ER capsule

Pain / Inflammation

What is indomethacin? Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID). Indomethacin is used to treat moderate to severe osteoarthritis, rheumatoid arthritis, gouty arthritis, or ankylosing spondylitis. Indomethacin is also used to treat shoulder pain caused by bursitis or tendinitis. Extended-release indomethacin (Indocin SR) should not be used to treat gouty arthritis. Indomethacin may also be used for purposes not listed in this medication guide. Warnings Indomethacin can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use indomethacin just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Indomethacin may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using indomethacin, especially in older adults. Before taking this medicine Indomethacin can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Indomethacin may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using indomethacin, especially in older adults. You should not use indomethacin if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID. Tell your doctor if you have ever had: heart disease, high blood pressure; a heart attack, stroke, or blood clot; fluid retention; bleeding problems; stomach ulcers or bleeding; asthma; liver or kidney disease; or if you smoke. If you are pregnant, you should not take indomethacin unless your doctor tells you to. Taking an NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy. This medicine may temporarily affect fertility (ability to have children) in women. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Indomethacin is not approved for use by anyone younger than 14 years old. How should I take indomethacin? Follow all directions on your prescription label and read all medication guides. Use the lowest dose that is effective in treating your condition. Swallow the extended-release capsule whole and do not crush, chew, break, or open it. Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Your dose needs may change if you switch to a different brand, strength, or form of indomethacin. Avoid medication errors by using only the form and strength your doctor prescribes. If you use this medicine long-term, you may need frequent medical tests. If you need surgery, tell your surgeon you currently use this medicine. You may need to stop for a short time. Store at room temperature away from moisture and heat. Do not allow the liquid medicine to freeze.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe drowsiness, stomach pain, or vomiting. What should I avoid while taking indomethacin? Avoid alcohol. Heavy drinking can increase your risk of stomach bleeding. Avoid taking aspirin unless your doctor tells you to. Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to indomethacin (such as aspirin, ibuprofen, ketoprofen, or naproxen). Indomethacin side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath. Stop using indomethacin and call your doctor at once if you have: a skin rash, no matter how mild; changes in your vision; heart problems--swelling, rapid weight gain, feeling short of breath; signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea, vomiting, diarrhea, unusual tiredness, itching, flu-like symptoms, dark urine, jaundice (yellowing of the skin or eyes); signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet. Common side effects may include: indigestion, nausea; headache; or dizziness. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect indomethacin? Ask your doctor before using indomethacin if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily. Ask a doctor or pharmacist before using indomethacin with any other medications, especially: cyclosporine; lithium; methotrexate; probenecid; heart or blood pressure medication, including a diuretic or "water pill"; a blood thinner--warfarin, Coumadin, Jantoven; or other NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, meloxicam, and others. This list is not complete. Other drugs may affect indomethacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Insulin Syringes (Prodigy

Diabetes

Insulin syringes There are a few things to keep in mind when buying insulin syringes. Insulin syringes are disposable and meant for one-time use. This helps make sure the needles are sterile to avoid the risk of infections from used needles. It’s also important to rotate injection sites to avoid lipohypertrophy, or an abnormal fat deposit under the skin. It’s a common complication with daily insulin injections. Insulin is given as a subcutaneous injection — or just under the skin — so the needle doesn’t go into muscle, which could affect your blood sugar levels. The best syringe size for you depends on your insulin dose. Since your insulin dose may change, going up or down depending on your blood sugar levels, you may need multiple syringe sizes to adjust your dose as needed. Insulin needles themselves also come in multiple sizes and thicknesses. What are the sizes for insulin syringes? Insulin syringes come in multiple sizes to deliver different doses of insulin. The number lines in an insulin syringe, measured in milliliters (mL), stand for the following: 0.3 mL syringes are for insulin doses under 30 units of insulin and are numbered at 1-unit intervals. 0.5 mL syringes are for 30 to 50 units of insulin and are numbered at 1-unit intervals. 1.0 mL are for doses more than 50 units of insulin and are numbered at 2 units per interval. The size of the barrel determines how much insulin a syringe holds, and the needle gauge determines the needle thickness. Thinner needles may be more comfortable to inject for some people. The length of a needle determines how far into your skin it penetrates. Needles for insulin only need to go just under your skin and not into muscle. Shorter needles are safer to avoid going into the muscle.  

Ipratropium / Albuterol Inhalation Solution

Respiratory Disease / Asthma

What is albuterol and ipratropium inhalation? Albuterol and ipratropium are bronchodilators that relax muscles in the airways and increase air flow to the lungs. Albuterol and ipratropium inhalation is used to prevent bronchospasm in people with chronic obstructive pulmonary disease (COPD) who are also using other medicines to control their condition. Albuterol and ipratropium inhalation may also be used for purposes not listed in this medication guide. Warnings Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working as well. Overuse of albuterol and ipratropium may increase the risk of death. It is critical that you use only the prescribed dose of albuterol and ipratropium. Before taking this medicine You should not use this medicine if you are allergic to albuterol, ipratropium, or atropine. Tell your doctor if you have ever had: heart disease, high blood pressure, coronary artery disease, or heart rhythm disorder; a seizure disorder such as epilepsy; diabetes; overactive thyroid; glaucoma; liver or kidney disease; or enlarged prostate, problems with urination. Tell your doctor if you are pregnant or breastfeeding. This medicine is not approved for use by anyone younger than 18 years old. How should I use albuterol and ipratropium inhalation? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Albuterol and ipratropium inhalation is usually used 4 times per day. Follow your doctor's dosing instructions very carefully. Do not use more than 6 inhalations in a 24-hour period. Overuse of albuterol and ipratropium may increase the risk of death. It is critical that you use only the prescribed dose of this medicine. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Always use the new inhaler device provided with your refill. To use the inhaler: You do not need to shake the inhaler before use. Uncap the mouthpiece of the inhaler. Breathe out fully. Put the mouthpiece into your mouth and close your lips. Keep your eyes closed to prevent spraying any medicine into your eyes. Breathe in slowly while pressing the dose-release button on the inhaler. Hold your breath for 10 seconds, then breathe out slowly. Close the cap until you use your inhaler again. Carefully follow all directions for cleaning your specific inhaler device once per week. Keep track of the number of sprays you have used. Throw away the Combivent Respimat inhaler canister after 3 months or 120 sprays, whichever comes first. To use the solution with a nebulizer: Open the foil pouch and remove one vial. Empty the medicine into the chamber of the nebulizer. Attach the mouthpiece or face mask, then attach the drug chamber to the compressor. Sit upright in a comfortable position. Place the mouthpiece into your mouth or put on the face mask, covering your nose and mouth. Turn on the compressor. Breathe in slowly and evenly until no more mist is formed by the nebulizer and the drug chamber is empty. Clean the nebulizer after each use. Follow the cleaning directions that came with your nebulizer. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working as well. To make sure this medicine is not causing harmful effects on your lungs, you may need to have chest X rays or other frequent lung function tests. Store at room temperature away from moisture, heat, and light. Do not freeze. Keep each vial in its foil pouch until you are ready to use it. Keep the cover on your inhaler when not in use. Keep away from open flame or high heat. The canister may explode if it gets too hot. Do not puncture or burn an empty inhaler canister. What happens if I miss a dose? Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of albuterol and ipratropium can be fatal. Overdose symptoms may include chest pain, fast or pounding heartbeats, tremors, dry mouth, extreme thirst, muscle weakness or limp feeling, severe headache, pounding in your neck or ears, or feeling like you might pass out. What should I avoid while using albuterol and ipratropium inhalation? If this medication gets in your eyes, rinse with water and seek medical attention. Avoid driving or hazardous activity until you know how albuterol and ipratropium will affect you. Your vision or reactions could be impaired. Albuterol and ipratropium inhalation side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: wheezing, choking, or other breathing problems after using this medicine; chest pain; fast or pounding heartbeats, fluttering in your chest; tremors, nervousness; swelling of your ankles or feet; blurred vision, tunnel vision, eye pain, or seeing halos around lights; painful or difficult urination; or low potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling. Common side effects may include: headache; trouble breathing; or cold symptoms such as stuffy nose, sneezing, cough, or sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Albuterol and ipratropium dosing information Usual Adult Dose for Chronic Obstructive Pulmonary Disease -- Maintenance: Inhalation Aerosol: 1 inhalation (albuterol-ipratropium bromide 100 mcg-20 mcg) orally four times a day. Additional inhalations can be taken as required. Maximum dose: 6 inhalations in 24 hours Inhalation solution: One 3 mL vial (albuterol-ipratropium bromide 2.5 mg-0.5 mg) four times a day via nebulization Maximum dose: Up to 2 additional 3 mL doses per day, if needed Comments: -The inhalation solution can be continued as medically indicated to control recurring bouts of bronchospasm. -If a previously effective regimen fails to provide the usual relief, medical advice should be sought immediately, as this is often a sign of worsening COPD and may require reassessment of therapy. Use: In patients with chronic obstructive pulmonary disease (COPD) on a regular aerosol bronchodilator who continue to have evidence of bronchospasm and who require a second bronchodilator   What other drugs will affect albuterol and ipratropium inhalation? Tell your doctor about all your other medicines, especially: a diuretic or "water pill"; heart or blood pressure medicine; other beta-blockers; or an antidepressant. This list is not complete. Other drugs may affect albuterol and ipratropium, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Irbesartan Tablet

Blood Pressure / Heart

What is irbesartan? Irbesartan is an angiotensin II receptor blocker (sometimes called an ARB). Irbesartan is used to treat high blood pressure (hypertension) in adults and children at least 6 years old. Lowering blood pressure may lower your risk of a stroke or heart attack. Irbesartan is also used to treat kidney problems caused by type 2 diabetes. Irbesartan may also be used for purposes not listed in this medication guide. Warnings Do not use if you are pregnant. Stop using and tell your doctor right away if you become pregnant. If you have diabetes, do not take irbesartan with any medication that contains aliskiren (a blood pressure medicine). Before taking this medicine You should not use irbesartan if you are allergic to it. If you have diabetes, do not take irbesartan with any medication that contains aliskiren (a blood pressure medicine). You may also need to avoid taking irbesartan with aliskiren if you have kidney disease. Tell your doctor if you have ever had: a heart condition other than one being treated with irbesartan; kidney disease (or if you are on dialysis); or if you are on a low-salt diet. Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Irbesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. If you plan to get pregnant, ask your doctor for a safer medicine to use before and during pregnancy. Having high blood pressure during pregnancy may cause complications in the mother and the baby. You should not breastfeed while using irbesartan. How should I take irbesartan? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Irbesartan may be taken with or without food. Your blood pressure will need to be checked often. Your kidney function may also need to be checked. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking irbesartan. It may take up to 2 weeks before your blood pressure is under control. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Treatment may also include diet, exercise, lowering cholesterol, not smoking, and controlling diabetes. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include fast heartbeats or fainting. What should I avoid while taking irbesartan? Do not use potassium supplements or salt substitutes, unless your doctor has told you to. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Irbesartan side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; little or no urination; high potassium level--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement. Common side effects may include: dizziness; feeling light-headed; or high potassium. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Irbesartan dosing information Usual Adult Dose for Hypertension: Initial dose: 150 mg orally once a day -Maintenance 150 to 300 mg orally once a day Maximum dose: 300 mg orally once a day Comments: -May be used alone or in combination with other antihypertensive agents. Use: Treatment of hypertension. Usual Adult Dose for Diabetic Nephropathy: 300 mg orally once a day Comments: -This drug has been shown to reduce the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or ESRD (need for dialysis or renal transplantation). Use: Treatment of diabetic nephropathy in patients with type 2 diabetes and hypertension with an elevated serum creatinine and proteinuria (greater than 300 mg/day).   What other drugs will affect irbesartan? Tell your doctor about all your other medicines, especially: heart or blood pressure medication; lithium; or NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect irbesartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Irbesartan/HCTZ Tablet

Blood Pressure / Fluid Retention

What is hydrochlorothiazide and irbesartan? Hydrochlorothiazide is a diuretic (water pill). Irbesartan is an angiotensin II receptor blocker (sometimes called an ARB blocker). Hydrochlorothiazide and irbesartan is a combination medicine used to treat high blood pressure (hypertension). Hydrochlorothiazide and irbesartan may also be used for purposes not listed in this medication guide. Warnings You should not use hydrochlorothiazide and irbesartan if you are unable to urinate, or if you are allergic to sulfa drugs. Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. If you have diabetes, do not use hydrochlorothiazide and irbesartan together with any medication that contains aliskiren (a blood pressure medicine). Before taking this medicine You should not use this medicine if you are allergic to irbesartan or hydrochlorothiazide, or: if you are unable to urinate; or if you are allergic to sulfa drugs. If you have diabetes, do not use hydrochlorothiazide and irbesartan together with any medication that contains aliskiren (a blood pressure medicine). You may also need to avoid taking hydrochlorothiazide and irbesartan with aliskiren if you have kidney disease. Tell your doctor if you have ever had: liver disease; congestive heart failure; glaucoma; low or high levels of potassium in your blood; asthma or allergies; high cholesterol or triglyceride levels; gout; lupus; diabetes; or an allergy to penicillin. Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Irbesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. You should not breastfeed while using this medicine. How should I take hydrochlorothiazide and irbesartan? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. You may take hydrochlorothiazide and irbesartan with or without food. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance. Your blood pressure will need to be checked often. Your blood and urine may also be tested if you have been vomiting or are dehydrated. If you need surgery or medical tests, tell the surgeon ahead of time that you are using hydrochlorothiazide and irbesartan. It may take up to 4 weeks for this medication to control your blood pressure. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include fast or slow heartbeat, feeling light-headed, or fainting. What should I avoid while taking hydrochlorothiazide and irbesartan? Hydrochlorothiazide may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis. Drinking alcohol can further lower your blood pressure and may cause side effects. Do not use potassium supplements or salt substitutes, unless your doctor has told you to. Hydrochlorothiazide and irbesartan side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. In rare cases, hydrochlorothiazide and irbesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Also call your doctor at once if you have: eye pain, vision problems; a light-headed feeling, like you might pass out; little or no urinating; jaundice (yellowing of the skin or eyes); easy bruising, unusual bleeding; or signs of an electrolyte imbalance--increased thirst or urination, confusion, vomiting, constipation, muscle pain or weakness, leg cramps, bone pain, lack of energy, irregular heartbeats, tingly feeling. Common side effects may include: dizziness; muscle or joint pain; or feeling tired. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.  

Isoniazid Tablet

Tuberculosis

What is isoniazid? Isoniazid is an antibiotic that fights bacteria. Isoniazid is used to treat and to prevent tuberculosis (TB). You may need to take other TB medicines in combination with isoniazid. When treating active TB, isoniazid must be used with other TB medicines. Tuberculosis can become resistant to treatment if isoniazid is used alone. Take all your medicines as prescribed by your doctor. Isoniazid may also be used for purposes not listed in this medication guide. Warnings You should not use isoniazid if you have active liver disease, or if you have taken isoniazid in the past and it caused liver problems, fever, chills, joint pain, or severe allergic reaction. Serious and sometimes fatal liver problems may occur during treatment with isoniazid or after you stop taking this medicine, especially if you are between the ages of 35 and 65. Your liver function may need to be checked every month while you are taking this medicine. Call your doctor right away if you have: nausea, upper stomach pain, loss of appetite, and feeling weak or tired. Avoid drinking alcohol. It may increase your risk of liver damage while you are taking isoniazid. Before taking this medicine You should not use isoniazid if you are allergic to it, or if you have: active liver disease; a history of severe allergic reaction to isoniazid; a history of hepatitis or other liver problems caused by taking isoniazid; or a history of severe isoniazid side effects such as fever, chills, or joint pain and swelling. To make sure isoniazid is safe for you, tell your doctor if you have: a history of liver disease; kidney disease; nerve problems that cause pain, weakness, or numbness; diabetes; HIV or AIDS; if you drink alcohol daily; if you are malnourished; if you use any drugs that are injected; or if you have ever had to stop taking isoniazid for any reason. If you are 35 years or older, your doctor will check your liver enzymes before you start treatment, to make sure you can safely use isoniazid. Serious and sometimes fatal liver problems may occur during treatment with isoniazid or after you stop taking this medication, even months after stopping. The risk of liver problems is highest in adults between the ages of 35 and 65. Serious liver problems may be more likely to occur in women, especially after childbirth, or in women of Hispanic or African-American ancestry. Ask your doctor about your specific risk. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Talk to your doctor if you will be breast-feeding a baby during your treatment with isoniazid. This medicine can pass into breast milk, but it will not treat or prevent tuberculosis in the nursing infant. How should I take isoniazid? Follow all directions on your prescription label. Do not take isoniazid in larger or smaller amounts or for longer than recommended. Take isoniazid on an empty stomach, at least 1 hour before or 2 hours after a meal. Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Isoniazid will not treat a viral infection such as the flu or a common cold. Your liver function may need to be checked every month while you are taking this medicine. Your doctor may have you take extra vitamin B6 while you are taking isoniazid. Take only the amount of vitamin B6 that your doctor has prescribed. Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. Detailed Isoniazid dosage information What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include vomiting, severe dizziness or drowsiness, slurred speech, blurred vision, hallucinations, trouble breathing, increased thirst, increased urination, fruity breath odor, or loss of consciousness. What should I avoid while taking isoniazid? Avoid drinking alcohol. It may increase your risk of liver damage while you are taking isoniazid. You may need to avoid certain foods while you are taking isoniazid. This includes red wine, aged cheese, dried meats, and tuna or other types of fish. Isoniazid side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. This reaction may occur several weeks after you began using isoniazid. Call your doctor at once if you have: sudden weakness or ill feeling, or fever for 3 days or longer; pain in your upper stomach (may spread to your back), nausea, loss of appetite; dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); vision changes, pain behind your eyes; confusion, memory problems, unusual thoughts or behavior; a seizure (convulsions); or pale skin, easy bruising or bleeding (nosebleeds, bleeding gums). Common side effects may include: numbness, tingling, or burning pain in your hands or feet; nausea, vomiting, upset stomach; or abnormal liver function tests. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Isoniazid side effects (more detail) What other drugs will affect isoniazid? Many drugs can interact with isoniazid. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with isoniazid. Give a list of all your medicines to any healthcare provider who treats you.

Isosorbide Mononitrate ER tablet

Heart Disease

What is isosorbide mononitrate? Isosorbide mononitrate is a nitrate that dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump. Isosorbide mononitrate is used to prevent angina attacks (chest pain). Isosorbide mononitrate will not treat an angina attack that has already begun. Warnings You should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking isosorbide mononitrate. Taking these medicines together can cause a sudden and serious decrease in blood pressure. Seek emergency medical attention if you have early symptoms of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, sweating, general ill feeling). Do not stop taking this medicine suddenly. Stopping suddenly could cause a severe angina attack. Isosorbide mononitrate can cause severe headaches, especially when you first start using it. These headaches may gradually become less severe as you continue to use the medication. Do not stop taking isosorbide mononitrate. Ask your doctor before using any headache pain medication. Use this medicine regularly to prevent an angina attack. Get your prescription refilled before you run out of medicine completely. Before taking this medicine You should not use isosorbide mononitrate if: you are allergic to isosorbide mononitrate, isosorbide dinitrate, or nitroglycerin; or you have early signs of a heart attack (chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating). You should not take erectile dysfunction medicine (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil) while you are taking isosorbide mononitrate. Taking these medicines together can cause a sudden and serious decrease in blood pressure. To make sure this medicine is safe for you, tell your doctor if you have: congestive heart failure; kidney disease; or low blood pressure. It is not known whether this medicine will harm an unborn baby, although animal studies have not shown harm. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether isosorbide mononitrate passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding. How should I take isosorbide mononitrate? Take isosorbide mononitrate exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended. If you use too much isosorbide mononitrate, it might stop working as well in controlling your condition. Try to rest or stay seated when you take this medicine (may cause dizziness or fainting). Do not crush, chew, or break an extended-release tablet. Swallow it whole. Not all brands and forms of isosorbide mononitrate are taken the same number of times per day. You may need to take the medicine only once daily, in the morning after getting out of bed. You may also need a second dose later in the day. Follow your doctor's dosing instructions very carefully. If your doctor changes your brand, strength, or type of isosorbide mononitrate, your dosage needs may change. Ask your pharmacist if you have any questions about the new brand of medicine you receive at the pharmacy. Use this medicine regularly to prevent an angina attack. Get your prescription refilled before you run out of medicine completely. You should not stop using isosorbide mononitrate suddenly or you could have a severe attack of angina. Keep this medicine on hand at all times. Get your prescription refilled before you run out of medicine completely. Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.   What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of isosorbide mononitrate can be fatal. Overdose symptoms may include a severe throbbing headache, fever, confusion, severe dizziness, fast or pounding heartbeats, vision problems, nausea, vomiting, stomach pain, bloody diarrhea, trouble breathing, sweating, cold or clammy skin, fainting, and seizure (convulsions). What to avoid This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Avoid drinking alcohol. Alcohol may increase certain side effects of isosorbide mononitrate (dizziness, drowsiness, feeling light-headed, or fainting). Isosorbide mononitrate side effects Get emergency medical help if you have signs of an allergic reaction to isosorbide mononitrate: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; worsening angina pain; fast or slow heart rate; or pounding heartbeats or fluttering in your chest. Isosorbide mononitrate can cause severe headaches. These headaches may gradually become less severe as you continue to use nitroglycerin. Do not stop taking this medicine to avoid headaches. Ask your doctor before using any headache pain medication. Common isosorbide mononitrate side effects may include: headache; dizziness upon standing; or flushing (warmth, redness, or tingly feeling). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect isosorbide mononitrate? Taking isosorbide mononitrate with certain other medicines can cause severely low blood pressure. This includes medicine to treat erectile dysfunction or pulmonary arterial hypertension. Serious, life-threatening side effects may occur. Tell your doctor about all your current medicines and any you start or stop using, especially: erectile dysfunction medication (including Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil, tadalafil, vardenafil, others); a diuretic or "water pill"; blood pressure medications including calcium channel blockers (such as nifedipine, Procardia); nitroglycerin; or riociguat (Adempas); This list is not complete. Other drugs may interact with isosorbide mononitrate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

  How can we help you?