What is chlorthalidone? Chlorthalidone is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Chlorthalidone treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. Chlorthalidone is also used to treat high blood pressure (hypertension). Chlorthalidone may also be used for purposes not listed in this medication guide. Warnings You should not use chlorthalidone if you are unable to urinate, or if you are allergic to sulfa drugs. Before taking this medicine You should not use chlorthalidone if you are allergic to it, or if: you are unable to urinate; or you are allergic to sulfa drugs. Tell your doctor if you have ever had: kidney disease; heart failure; gout; high cholesterol or triglycerides; diabetes; or if you are on a low-salt diet. Tell your doctor if you are pregnant or plan to become pregnant. Taking chlorthalidone during pregnancy may cause side effects in the newborn baby, such as jaundice (yellowing of the skin or eyes), bruising or bleeding, low blood sugar, or an electrolyte imbalance. Do not start or stop taking chlorthalidone during pregnancy without your doctor's advice. Although chlorthalidone may cause side effects in a newborn, having high blood pressure during pregnancy can cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating hypertension may outweigh any risks to the baby. You should not breastfeed while using chlorthalidone. How should I take chlorthalidone? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking chlorthalidone. This can lead to very low blood pressure, a serious electrolyte imbalance, or kidney failure. Your blood pressure will need to be checked often. Your blood and urine may both be tested if you have been vomiting or are dehydrated. chlorthalidone can affect the results of certain medical tests. Tell any doctor who treats you that you are using chlorthalidone. If you need surgery, tell your surgeon you currently use this medicine. If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store this medicine at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, weakness, dizziness, drowsiness, extreme thirst, muscle pain, or rapid heartbeats. What should I avoid while taking chlorthalidone? Drinking alcohol with chlorthalidone can cause side effects. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. Chlorthalidone side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; low sodium--headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady; low potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling; low magnesium--dizziness, irregular heartbeats, feeling jittery, muscle cramps, muscle spasms, cough or choking feeling; or kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath. Common side effects may include: low blood pressure (feeling light-headed); kidney problems; dizziness; or an electrolyte imbalance (such as low levels of potassium, sodium, or magnesium in your blood). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Chlorthalidone dosing information Usual Adult Dose for Hypertension: -Initial dose: 25 mg orally once a day -Titration: Increase to 50 mg orally once a day if response is inadequate; if response is still inadequate, increase to 100 mg orally once a day, or a second antihypertensive drug (step 2 therapy) may be added -Maintenance dose: 25 to 100 mg orally once a day -Maximum dose: 100 mg orally once a day Comments: -Doses should be taken in the morning with food. -Maintenance doses may be lower than initial doses and should be adjusted according to individual patient response. -Effectiveness is well sustained during continued use. Use: Hypertension (alone or with another antihypertensive drug) Usual Adult Dose for Edema: -Initial dose: 50 to 100 mg orally once a day, or 100 mg orally every other day; some patients may require 150 to 200 mg orally at these intervals -Maximum dose: 200 mg orally once a day Comments: -Doses should be taken in the morning with food. -Maintenance doses may be lower than initial doses and should be adjusted according to individual patient response. -Effectiveness is well sustained during continued use. Use: For edema due to various forms of renal dysfunction, such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure   What other drugs will affect chlorthalidone? Using chlorthalidone with other drugs that make you light-headed can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: other blood pressure medications; lithium; digoxin, digitalis; insulin or oral diabetes medicine; or steroid medicine. This list is not complete. Other drugs may affect chlorthalidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is chlorzoxazone? Chlorzoxazone is a muscle relaxer that is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury. Chlorzoxazone may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Before taking this medicine You should not use chlorzoxazone if you are allergic to it. Tell your doctor if you have ever had: liver disease. Tell your doctor if you are pregnant or breast-feeding. Chlorzoxazone is not approved for use by anyone younger than 18 years old. How should I take chlorzoxazone? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Chlorzoxazone is usually taken 3 or 4 times per day. Follow your doctor's dosing instructions very carefully. Chlorzoxazone is only part of a complete program of treatment that may also include rest, physical therapy, or other pain relief measures. Follow your doctor's instructions. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, diarrhea, severe drowsiness, headache, muscle weakness, shallow breathing, or fainting. What should I avoid while taking chlorzoxazone? Drinking alcohol with chlorzoxazone can cause side effects. Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Chlorzoxazone side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have: a light-headed feeling, like you might pass out; skin rash, itching, or redness; liver problems--stomach pain (upper right side), loss of appetite, vomiting, fever, unusual tiredness, dark urine, or jaundice (yellowing of the skin or eyes); or signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds. Common side effects may include: drowsiness; dizziness; or general ill feeling. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Chlorzoxazone dosing information Usual Adult Dose for Muscle Spasm: Initial dose: 250 to 500 mg orally 3 to 4 times a day -If inadequate response, may increase to 750 mg orally 3 or 4 times a day Comments: -The dose should be reduced as improvement occurs. Use: As an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions.   What other drugs will affect chlorzoxazone? Using chlorzoxazone with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Other drugs may affect chlorzoxazone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is cilostazol? Cilostazol is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). Cilostazol dilates arteries that supply blood to your legs. Cilostazol also improves circulation by keeping platelets in the blood from sticking together and clotting. Cilostazol is used to treat the symptoms of intermittent claudication. This condition causes reduced blood flow to the legs, leading to pain while walking. Cilostazol improves your ability to walk longer distances without pain. Cilostazol may also be used for purposes not listed in this medication guide. Warnings Do not take cilostazol if you have heart failure of any kind. Before taking this medicine You should not take cilostazol if you have heart failure of any kind. Cilostazol can make this condition worse. Tell your doctor if you have ever had: bleeding problems; liver or kidney disease; a heart attack or stroke; or if you smoke. It is not known whether cilostazol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. You should not breastfeed while using cilostazol. How should I take cilostazol? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Cilostazol is usually taken twice a day on an empty stomach, at least 30 minutes before or 2 hours after breakfast or dinner. Take the medicine at the same time each day. It may take up to 12 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 3 months of treatment. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking cilostazol? Grapefruit may interact with cilostazol and lead to unwanted side effects. Avoid the use of grapefruit products. Cilostazol side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: chest pain, pounding heartbeats or fluttering in your chest; a light-headed feeling, like you might pass out; fever, chills, sore throat, mouth sores; or easy bruising, unusual bleeding, purple or red spots under your skin. Common side effects may include: diarrhea, abnormal bowel movements; headache; or fast or pounding heartbeats. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Cilostazol dosing information Usual Adult Dose for Intermittent Claudication: 100 mg orally twice a day at least 30 minutes before or 2 hours after breakfast and dinner Comments: -Patients may respond as early as 2 to 4 weeks after initiation of therapy, but treatment for up to 12 weeks may be required before a beneficial effect is experienced. -If symptoms remain unimproved after 3 months, discontinue this drug. Use: Reduction of symptoms of intermittent claudication, as demonstrated by an increased walking distance.   What other drugs will affect cilostazol? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Many drugs can affect cilostazol. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is citalopram? Citalopram is an antidepressant belonging to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Citalopram is a prescription medicine used to treat depression. Citalopram is also used to treat major depressive disorder (MDD). Warnings Citalopram can cause a serious heart problem. Call your doctor right away if you have chest pain, fast or pounding heartbeats, shortness of breath, and sudden dizziness. You should not use citalopram if you also take pimozide, as the combination can cause problems with your heart rhythm. Do not use citalopram if you have used a MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine) or have received a methylene blue injection. A fatal reaction may occur. People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Do not stop using citalopram without first asking your doctor. Before taking this medicine You should not use citalopram if you are allergic to citalopram or escitalopram (Lexapro), or if you also take pimozide. Do not use citalopram within 2 weeks before or after using an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine. To make sure citalopram is safe for you, tell your doctor if you have ever had: heart problems; long QT syndrome (in you or a family member); high blood pressure; a stroke; bleeding problems; sexual problems; liver or kidney disease; narrow-angle glaucoma; seizures or epilepsy; bipolar disorder (manic depression); or an electrolyte imbalance (such as low levels of potassium, magnesium, or sodium in your blood). Tell your doctor if you also use stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with citalopram could cause a serious condition called serotonin syndrome. People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Stay alert to changes in your mood or symptoms. Your family or caregivers should also watch for sudden changes in your behavior. Taking this medicine during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop citalopram without asking your doctor. You should not breastfeed while taking . How should I take citalopram? Take citalopram exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Measure liquid medicine with the supplied measuring device (not a kitchen spoon). Your symptoms may not improve for up to 4 weeks. Tell your doctor if you have any changes in sexual function, such as loss of interest in sex, trouble having an orgasm, or (in men) problems with erections or ejaculation. Some sexual problems can be treated. If you stop using citalopram suddenly, you may have unpleasant symptoms (such as agitation, confusion, tingling or electric shock feelings). Ask your doctor before stopping the medicine. Store at room temperature away from moisture and heat. Dosing information Usual Adult Dose for Depression: Initial dose: 20 mg orally once a day Maintenance dose: 20 to 40 mg orally once a day Maximum dose: 40 mg orally per day Comments: -The initial dose may be increased if necessary to 40 mg once a day after at least 1 week of therapy. -Doses of 60 mg/day did not demonstrate an advantage in efficacy over 40 mg/day doses. -Acute episodes of depression may require several months or more of sustained pharmacologic therapy Use: Treatment of depression Usual Geriatric Dose for Depression: Over 60 years of age: Recommended dose: 20 mg orally once a day Comments: -Doses of 60 mg/day did not demonstrate an advantage in efficacy over 40 mg/day doses. -Acute episodes of depression may require several months or more of sustained pharmacologic therapy. Use: Treatment of depression   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking citalopram? Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen, naproxen, Advil, Aleve, Motrin, and others. Using an NSAID with citalopram may cause you to bruise or bleed easily. Avoid drinking alcohol. Avoid driving or hazardous activity until you know how citalopram will affect you. Your reactions could be impaired. Citalopram side effects Get emergency medical help if you have signs of an allergic reaction to citalopram: hives, rash, blisters; fever, joint pain; difficult breathing; swelling of your face, lips, tongue, or throat. Tell your doctor right away if you have new or sudden changes in mood or behavior, including new or worse depression or anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, more active or talkative, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: a light-headed feeling, like you might pass out; blurred vision, eye pain or redness, seeing halos around lights; fast or pounding heartbeats, pain or fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out); a seizure; manic episodes - racing thoughts, increased energy, decreased need for sleep, risk-taking behavior, being agitated or talkative; severe nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors; or low blood sodium - headache, confusion, problems with thinking or memory, weakness, feeling unsteady. Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Common citalopram side effects may include: sexual problems; dizziness, drowsiness; dry mouth, thirst, increased sweating or urination; loss of appetite, nausea, diarrhea, constipation; feeling anxious, agitated, or shaky; feeling weak or tired; sleep problems (insomnia); yawning; increased muscle movement; nosebleeds, heavy menstrual bleeding; or cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect citalopram? Citalopram can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Tell your doctor about all your current medicines. Many other drugs can affect citalopram, especially: cimetidine; a blood thinner (warfarin, Coumadin, Jantoven); a diuretic or "water pill"; lithium; St. John's wort; tramadol; or tryptophan (sometimes called L-tryptophan). This list is not complete and many other drugs may affect citalopram. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is clobetasol topical? Clobetasol is a highly potent corticosteroid that helps reduce inflammation in the body. Clobetasol topical (for the skin) is used to treat inflammation and itching caused by plaque psoriasis and skin conditions that respond to corticosteroid medication. It is available in a cream, gel, ointment, lotion, solution, foam or spray. Warnings Do not use clobetasol topical to treat acne, rosacea, or a rash around the mouth. Use care when putting on a large part of the skin or where there are open wounds. Talk with the doctor. Clobetasol may cause harm if swallowed. If swallowed, call a doctor or poison control center right away. This drug may raise the chance of cataracts or glaucoma. Talk with your doctor. It may affect growth in children and teens in some cases. They may need regular growth checks. If you are breast-feeding, do not apply clobetasol cream, gel, ointment, lotion, solution, foam or spray to the nipple or the area around it. Before taking this medicine You should not use clobetasol topical if you are allergic to it. To make sure this drug is safe for you, tell your doctor if you have ever had: any type of skin infection; a skin reaction to any steroid medicine; liver disease; or an adrenal gland disorder. Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes. It is not known whether clobetasol topical will harm an unborn baby. Tell your doctor if you are pregnant. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply this drug to your chest, avoid areas that may come into contact with the baby's mouth. Clobetasol is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects. How should I use clobetasol? Use this drug exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth. Do not use clobetasol on broken or infected skin. Also avoid using this medicine in open wounds. Wash your hands before and after using this drug, unless you are using the medicine to treat the skin on your hands. Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to. Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects. If you are treating the diaper area, do not use plastic pants or tight-fitting diapers. This medicine is for short-term use only (2 weeks, or up to 4 weeks for scalp psoriasis). Follow your doctor's dosing instructions very carefully. If you use clobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled. Call your doctor if your symptoms do not improve, or if they get worse. You should not stop using this drug suddenly. Follow your doctor's instructions about tapering your dose. Store at room temperature away from moisture and heat. Keep from freezing. Clobetasol foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.   What happens if I miss a dose? Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. High doses or long-term use of clobetasol can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid while using clobetasol? Avoid applying clobetasol topical to your face, underarms, or groin area. Do not use this medicine to treat any condition that has not been checked by your doctor. Avoid using other topical steroid medications on the areas you treat with clobetasol unless your doctor tells you to. Clobetasol side effects Get emergency medical help if you have signs of an allergic reaction to clobetasol: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: worsening of your skin condition; redness, warmth, swelling, oozing, or severe irritation of any treated skin; blurred vision, tunnel vision, eye pain, or seeing halos around lights; high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; or possible signs of absorbing this medicine through your skin - weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes. Common side effects may include: burning, itching, swelling, or irritation of treated skin; dry or cracking skin; redness or crusting around your hair follicles; spider veins; stretch marks, thinning skin; rash or hives; acne; or temporary hair loss. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect clobetasol? Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

What is clobetasol topical? Clobetasol is a highly potent corticosteroid that helps reduce inflammation in the body. Clobetasol topical (for the skin) is used to treat inflammation and itching caused by plaque psoriasis and skin conditions that respond to corticosteroid medication. It is available in a cream, gel, ointment, lotion, solution, foam or spray. Warnings Do not use clobetasol topical to treat acne, rosacea, or a rash around the mouth. Use care when putting on a large part of the skin or where there are open wounds. Talk with the doctor. Clobetasol may cause harm if swallowed. If swallowed, call a doctor or poison control center right away. This drug may raise the chance of cataracts or glaucoma. Talk with your doctor. It may affect growth in children and teens in some cases. They may need regular growth checks. If you are breast-feeding, do not apply clobetasol cream, gel, ointment, lotion, solution, foam or spray to the nipple or the area around it. Before taking this medicine You should not use clobetasol topical if you are allergic to it. To make sure this drug is safe for you, tell your doctor if you have ever had: any type of skin infection; a skin reaction to any steroid medicine; liver disease; or an adrenal gland disorder. Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes. It is not known whether clobetasol topical will harm an unborn baby. Tell your doctor if you are pregnant. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply this drug to your chest, avoid areas that may come into contact with the baby's mouth. Clobetasol is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects. How should I use clobetasol? Use this drug exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth. Do not use clobetasol on broken or infected skin. Also avoid using this medicine in open wounds. Wash your hands before and after using this drug, unless you are using the medicine to treat the skin on your hands. Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to. Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects. If you are treating the diaper area, do not use plastic pants or tight-fitting diapers. This medicine is for short-term use only (2 weeks, or up to 4 weeks for scalp psoriasis). Follow your doctor's dosing instructions very carefully. If you use clobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled. Call your doctor if your symptoms do not improve, or if they get worse. You should not stop using this drug suddenly. Follow your doctor's instructions about tapering your dose. Store at room temperature away from moisture and heat. Keep from freezing. Clobetasol foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin. Detailed Clobetasol topical dosage information What happens if I miss a dose? Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. High doses or long-term use of clobetasol can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid while using clobetasol? Avoid applying clobetasol topical to your face, underarms, or groin area. Do not use this medicine to treat any condition that has not been checked by your doctor. Avoid using other topical steroid medications on the areas you treat with clobetasol unless your doctor tells you to. Clobetasol side effects Get emergency medical help if you have signs of an allergic reaction to clobetasol: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: worsening of your skin condition; redness, warmth, swelling, oozing, or severe irritation of any treated skin; blurred vision, tunnel vision, eye pain, or seeing halos around lights; high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; or possible signs of absorbing this medicine through your skin - weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes. Common side effects may include: burning, itching, swelling, or irritation of treated skin; dry or cracking skin; redness or crusting around your hair follicles; spider veins; stretch marks, thinning skin; rash or hives; acne; or temporary hair loss. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Clobetasol topical side effects (more detail) What other drugs will affect clobetasol? Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

What is calcitriol? Calcitriol is a form of vitamin D3. Vitamin D helps your body absorb calcium from the stomach. Calcitriol is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people who have chronic kidney failure and are not receiving dialysis. Calcitriol is also used to treat calcium deficiency in people with hypoparathyroidism (underactive parathyroid glands) caused by surgery, disease, or other conditions. Calcitriol is also used to treat calcium deficiency (hypocalcemia) and metabolic bone disease in people who are receiving dialysis. Calcitriol may also be used for purposes not listed in this medication guide. Warnings You should not use calcitriol if you have high levels of calcium or vitamin D in your blood, or if you have ever had an allergic reaction to calcitriol or other forms of vitamin D. Before taking this medicine You should not use calcitriol if: you have high levels of calcium or vitamin D in your blood; or you have had an allergic reaction to calcitriol or other forms of vitamin D. Tell your doctor about all your medical conditions or allergies. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. You should not breastfeed while using calcitriol. Do not give this medicine to a child without medical advice. How should I use calcitriol? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Calcitriol oral is taken by mouth. Measure oral liquid carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Calcitriol injection is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself. Read and carefully follow any Instructions for Use provided with your medicine. Prepare an injection only when you are ready to give it. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine. You will need frequent medical tests. Drink plenty of fluids unless your doctor has told you to restrict your fluid intake. You may need to follow a special diet while using calcitriol. Follow all instructions of your doctor or dietitian. Learn about the foods to eat or avoid to help control your condition. Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking calcitriol. This can lead to very low blood pressure, a serious electrolyte imbalance, or kidney failure. If you need major surgery or will be on long-term bed rest, your dose or testing needs may change. Follow your doctor's instructions. Store at room temperature away from moisture, heat, and light.   What happens if I miss a dose? Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Early signs of overdose may include headache, weakness, drowsiness, dry mouth, metallic taste, nausea, vomiting, constipation, stomach pain, loss of appetite, muscle pain, or bone pain. Late signs of overdose may include increased thirst, itching, increased urination (especially at night), severe stomach pain spreading to your back, irregular heartbeats, loss of appetite, weight loss, feeling hot, decreased interest in sex, or being unable to urinate. What should I avoid while using calcitriol? Do not take other vitamin or mineral supplements unless your doctor has told you to. Ask your doctor before using an antacid or laxative, especially if you are on dialysis. Taking antacids or laxatives that contain magnesium may increase your blood levels of magnesium, which could affect your heart or blood pressure. Calcitriol side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using calcitriol and call your doctor at once if you have: dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; high calcium levels--nausea, vomiting, constipation, increased thirst or urination, muscle weakness, bone pain, confusion, lack of energy, or tired feeling; or low calcium level--muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes). Calcitriol can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using calcitriol. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect calcitriol? Tell your doctor about all your other medicines, especially: cholestyramine; digoxin, digitalis; ketoconazole; a diuretic or "water pill"--hydrochlorothiazide, HCTZ, Diovan HCT, Hyzaar, Maxzide, Tenoretic, Zestoretic, and others; seizure medicine--phenobarbital, phenytoin; or steroid medicine--prednisone, dexamethasone, fluticasone, and others. This list is not complete. Other drugs may affect calcitriol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is clomiphene? Clomiphene is a non-steroidal fertility medicine. It causes the pituitary gland to release hormones needed to stimulate ovulation (the release of an egg from the ovary). Clomiphene is used to cause ovulation in women with certain medical conditions (such as polycystic ovary syndrome) that prevent naturally occurring ovulation. Clomiphene may also be used for purposes not listed in this medication guide. Warnings Do not use clomiphene if you are already pregnant. You should not use clomiphene if you have: liver disease, unexplained abnormal vaginal bleeding, an uncontrolled adrenal gland or thyroid disorder, an ovarian cyst (unrelated to polycystic ovary syndrome), or if you are pregnant. Before taking this medicine You should not use clomiphene if you are allergic to it, or if you have: unexplained abnormal vaginal bleeding; an ovarian cyst that is not related to polycystic ovary syndrome; past or present liver disease; a pituitary gland or other brain tumor; an untreated or uncontrolled problem with your thyroid or adrenal gland; or if you are pregnant. To make sure clomiphene is safe for you, tell your doctor if you have: endometriosis or uterine fibroids. Do not use clomiphene if you are already pregnant. Talk to your doctor if you have concerns about the possible effects of this medicine on a new pregnancy. Clomiphene can pass into breast milk and may harm a nursing baby. This medication may slow breast milk production in some women. Tell your doctor if you are breast-feeding a baby. Using clomiphene for longer than 3 treatment cycles may increase your risk of developing an ovarian tumor. Ask your doctor about your specific risk. Higher doses of clomiphene can also lead to visual disturbances, which may be irreversible, or a condition called ovarian hyperstimulation syndrome (OHSS). OHSS can be a life threatening condition. Symptoms include abdominal pain, bloating, nausea, weight gain, and trouble breathing. Fertility treatment may increase your chance of having multiple births (twins, triplets). These are high-risk pregnancies both for the mother and the babies. Ask your doctor about this risk. How should I take clomiphene? Use clomiphene exactly as directed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Your doctor will perform medical tests to make sure you do not have conditions that would prevent you from safely using clomiphene. Clomiphene is usually taken for 5 days, starting on the 5th day of your menstrual period. Follow your doctor's instructions. You will need to have a pelvic examination before each treatment cycle. You must remain under the care of a doctor while you are using this medicine. You will most likely ovulate within 5 to 10 days after you take clomiphene. To improve your chance of becoming pregnant, you should have sexual intercourse while you are ovulating. Follow your doctor’s instructions regarding timed intercourse. Your doctor may have you use over-the-counter ovulation tests or check your temperature each morning and record your daily readings on a chart. This will help you determine when you can expect ovulation to occur. In most cases, clomiphene should not be used for more than 3-6 treatment cycles (3 ovulatory cycles). If ovulation occurs but you do not get pregnant after 3 treatment cycles, your doctor may stop treatment and evaluate your infertility further. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Call your doctor for instructions if you miss a dose of clomiphene. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose may result in nausea, vomiting, hot flashes, blurring or spots in your vision, or abdominal pain. What should I avoid? This medication may cause blurred vision. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Clomiphene side effects Get emergency medical help if you have any signs of an allergic reaction to clomiphene: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Some women using this medicine develop a condition called ovarian hyperstimulation syndrome (OHSS), especially after the first treatment. OHSS can be a life threatening condition. Call your doctor right away if you have any of the following symptoms of OHSS: stomach pain, bloating; nausea, vomiting, diarrhea; rapid weight gain, especially in your face and midsection; little or no urinating; or pain when you breathe, rapid heart rate, feeling short of breath (especially when lying down). Stop using clomiphene and call your doctor at once if you have: pelvic pain or pressure, enlargement in your pelvic area; vision problems; seeing flashes of light or "floaters" in your vision; increased sensitivity of your eyes to light; or heavy vaginal bleeding. Common clomiphene side effects may include: flushing (warmth, redness, or tingly feeling); breast pain or tenderness; headache; or breakthrough bleeding or spotting. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Clomiphene side effects (more detail) Dosing information Usual Adult Dose for Ovulation Induction: 50 mg orally once a day for 5 days. Therapy should be initiated on or near the 5th day of the menstrual cycle, but may be started at any time in patients without recent uterine bleeding. If ovulation occurs and pregnancy is not achieved, up to 2 additional courses of clomiphene 50 mg orally once a day for 5 days may be administered. Each subsequent course may be started as early as 30 days after the previous course and after pregnancy has been excluded. Most patients ovulate following the first course of therapy. However, if the patient fails to ovulate, a second course of 100 mg/day for 5 days may be given as early as 30 days following the initial course. A third course of 100 mg/day for 5 days may be given after 30 days, if necessary.   What other drugs will affect clomiphene? Other drugs may interact with clomiphene, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What is clomipramine? Clomipramine is a tricyclic antidepressant that is used to treat symptoms of obsessive-compulsive disorder (OCD), such as recurrent thoughts or feelings and repetitive actions. Clomipramine is for use in adults and children at least 10 years old. Clomipramine may also be used for purposes not listed in this medication guide. Warnings You should not use clomipramine if you have recently had a heart attack. Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor. Before taking this medicine You should not use clomipramine if you are allergic to it, or if you have: you have recently had a heart attack; or you are allergic to antidepressants such as amitriptyline, amoxapine, trimipramine, desipramine, doxepin, imipramine, nortriptyline, or protriptyline. Do not use clomipramine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone. Tell your doctor if you have ever had: liver disease; kidney disease; bipolar disorder (manic-depression), schizophrenia or other mental illness; alcoholism; a seizure or a head injury; heart disease; low blood pressure; narrow-angle glaucoma; overactive thyroid or adrenal gland tumor (pheochromocytoma or neuroblastoma); or urination problems. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with clomipramine and cause a serious condition called serotonin syndrome. Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Tell your doctor if you are pregnant or plan to get pregnant. Taking this medicine during late pregnancy may cause withdrawal symptoms in the newborn. You should not breastfeed while using clomipramine. How should I take clomipramine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment. Call your doctor if your symptoms do not improve, or if they get worse. If you need surgery, tell your surgeon you currently use clomipramine. You may need to stop for a short time. Do not stop using clomipramine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine. Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of clomipramine can be fatal. Overdose symptoms may include irregular heartbeats, feeling restless or agitated, confusion, severe sweating, slow or jerky muscle movements, extreme drowsiness, slow breathing, feeling like you might pass out, seizure, or coma. What should I avoid while taking clomipramine? Avoid drinking alcohol. Dangerous side effects could occur. Avoid driving or hazardous activity until you know how clomipramine will affect you. Your reactions could be impaired. Clomipramine side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: low sodium level --headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady; blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights; confusion, extreme fear, thoughts of hurting yourself; pain or burning when you urinate; or a seizure (convulsions). Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Common side effects may include: feeling dizzy, drowsy, tired, or nervous; tremors, jerking muscle movements; sweating; changes in appetite or weight; urination problems; vision changes; or decreased sex drive, impotence, or difficulty having an orgasm. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Clomipramine side effects (more detail) Clomipramine dosing information Usual Adult Dose for Obsessive Compulsive Disorder: Initial dose: 25 mg orally once a day at bedtime Maintenance dose: 100 mg orally per day Maximum dose: 250 mg/day Comments: -The dose should be increased gradually, as tolerated, to 100 mg during the first 2 weeks. After the initial titration, the dose may be increased gradually over the next several weeks to a maximum of 250 mg/day. -During initial titration, this drug should be given in divided doses with meals to reduce gastrointestinal side effects. -During maintenance, the total daily dose may be given once a day at bedtime to minimize daytime sedation. -Dosage adjustments should be made to maintain the patient on the lowest effective dosage. Use: Treatment of obsessions and compulsions in patients with Obsessive-Compulsive Disorder (OCD) who have obsessions/compulsions that must cause marked distress, be time consuming, or significantly interfere with social/occupational functioning Usual Pediatric Dose for Obsessive Compulsive Disorder: 10 to 17 years: -Initial dose: 25 mg orally once a day at bedtime -Maintenance dose: May increase to 3 mg/kg or 100 mg orally per day, whichever is the smaller dose -Maximum dose: 3 mg/kg/day or 200 mg/day, whichever is the smaller dose Comments: -During initial titration, this drug should be given in divided doses with meals to reduce gastrointestinal side effects. -After titration, the total daily dose may be given once a day at bedtime to minimize daytime sedation. -Dosage adjustments should be made to maintain the patient on the lowest effective dosage. Use: Treatment of obsessions and compulsions in patients with OCD who have obsessions/compulsions that must cause marked distress, be time consuming, or significantly interfere with social/occupational functioning Detailed Clomipramine dosage information What other drugs will affect clomipramine? Using clomipramine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Many drugs can affect clomipramine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is clonazepam? Clonazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that benzodiazepines work by enhancing the activity of certain neurotransmitters in the brain. Clonazepam is used to treat certain seizure disorders (including absence seizures or Lennox-Gastaut syndrome) in adults and children. Clonazepam is also used to treat panic disorder (including agoraphobia) in adults. Warnings Clonazepam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. MISUSE OF CLONAZEPAM CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Never share clonazepam with another person. Selling or giving away this medicine is against the law. Some people have thoughts about suicide while taking clonazepam. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide. Get medical help right away if you stop using clonazepam and have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, or thoughts about suicide. Do not stop using clonazepam without asking your doctor. You may have life-threatening withdrawal symptoms if you stop using the medicine suddenly after long-term use. Some withdrawal symptoms may last up to 12 months or longer. Before taking this medicine You should not take clonazepam if you allergic to it or if you have: narrow-angle glaucoma; severe liver disease; or a history of allergic reaction to any benzodiazepine (including alprazolam, diazepam, lorazepam, Valium, Xanax, Versed, and others). To make sure this medicine is safe for you, tell your doctor if you have ever had: kidney or liver disease; breathing problems; depression, mood problems, or suicidal thoughts or behavior; or porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system). Some people have thoughts about suicide while taking clonazepam. Stay alert to changes in your mood or symptoms. Your family or caregivers should also watch for sudden changes in your behavior. Tell your doctor if you are pregnant or plan to become pregnant. If you use clonazepam during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks. Do not start or stop seizure medication during pregnancy without your doctor's advice. Clonazepam may harm an unborn baby, but having a seizure during pregnancy could harm both mother and baby. Preventing seizures may outweigh these risks. Tell your doctor right away if you become pregnant. Ask a doctor if it is safe to breastfeed while using this medicine. Do not give this medicine to a child without medical advice. Clonazepam is not approved to treat panic disorder in anyone younger than 18 years old. How should I take clonazepam? Take clonazepam exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Never use this medicine in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of this medicine. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. You will need frequent medical tests. Do not stop using clonazepam suddenly, even if you feel fine. Stopping suddenly may cause increased seizures or unpleasant withdrawal symptoms. Follow your doctor's instructions about tapering your dose. Swallow the regular tablet whole, with a full glass of water. Clonazepam doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight. Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves. Your doctor will need to check your progress on a regular basis. Call your doctor if this medicine seems to stop working as well in treating your seizures or panic attacks. Seizures are often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Store at room temperature away from moisture, heat, and light. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of clonazepam can be fatal if you take it with alcohol, opioid medicine, or other drugs that cause drowsiness or slow your breathing. Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, or coma. What should I avoid while taking clonazepam? Do not drink alcohol. Dangerous side effects or death could occur. Avoid driving or hazardous activity until you know how clonazepam will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Clonazepam side effects Get emergency medical help if you have signs of an allergic reaction to clonazepam: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Clonazepam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up. Tell your doctor right away if you have new or sudden changes in mood or behavior, including new or worse depression or anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, more active or talkative, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: new or worsening seizures; severe drowsiness; weak or shallow breathing; unusual changes in mood or behavior; confusion, paranoia, nightmares, hallucinations; thoughts of suicide or hurting yourself; unusual or involuntary eye movements. Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury. Common clonazepam side effects may include: drowsiness, dizziness; feeling tired or depressed; memory problems; or problems with walking or coordination. After you stop using clonazepam, get medical help right away if you have symptoms such as: unusual muscle movements, being more active or talkative, sudden and severe changes in mood or behavior, confusion, hallucinations, seizures, suicidal thoughts or actions. Some withdrawal symptoms may last up to 12 months or longer after stopping this medicine suddenly. Tell your doctor if you have ongoing anxiety, depression, problems with memory or thinking, trouble sleeping, ringing in your ears, a burning or prickly feeling, or a crawling sensation under your skin. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect clonazepam? Using clonazepam with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Other drugs may interact with clonazepam, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

What is clonidine? Clonidine lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels to relax and your heart to beat more slowly and easily. Clonidine is used to treat hypertension (high blood pressure). The Kapvay brand is used to treat attention deficit hyperactivity disorder (ADHD). Clonidine is sometimes given with other medications. Clonidine is also available as a transdermal patch worn on the skin. Do not use two forms of this medicine at the same time. Warnings Before you take clonidine, tell your doctor if you have heart disease or severe coronary artery disease, a heart rhythm disorder, slow heartbeats, low blood pressure, a history of heart attack or stroke, kidney disease, or if you have ever had an allergic reaction to a Catapres TTS transdermal skin patch. Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies. Before taking this medicine You should not take this medicine if you are allergic to clonidine. To make sure clonidine is safe for you, tell your doctor if you have: heart disease or severe coronary artery disease; a heart rhythm disorder, slow heartbeats; high or low blood pressure, or a history of fainting spells; a heart attack or stroke; pheochromocytoma (tumor of the adrenal gland); kidney disease; or if you have ever had an allergic reaction to a Catapres TTS transdermal skin patch. It is not known if clonidine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of clonidine on the baby. Clonidine may affect fertility in men or women. Pregnancy could be harder to achieve while either parent is using this medicine. If you are breastfeeding, tell your doctor if you notice somnolence, tiredness, rapid breathing, and poor feeding in the nursing baby. Catapres is not approved for use by anyone younger than 18 years old. Do not give Kapvay to a child younger than 6 years old. How should I take clonidine? Take clonidine exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Clonidine is usually taken in the morning and at bedtime. If you take different doses of this medicine at each dosing time, it may be best to take the larger dose at bedtime. Clonidine may be taken with or without food. Swallow the extended-release tablet whole and do not crush, chew, or break it. Tell your doctor if you have a planned surgery. You may have withdrawal symptoms if you stop using this medicine suddenly. Ask your doctor before stopping the medicine. Call your doctor if you are sick with vomiting. This is especially important for a child taking clonidine. If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. Store at room temperature away from moisture, heat, and light. Dosing information Usual Adult Dose for Hypertension: Oral: -Initial dose: 0.1 mg orally 2 times a day (morning and bedtime) -Titration: Increments of 0.1 mg orally per day may be made at weekly intervals to desired response -Maintenance dose: 0.2 to 0.6 mg orally per day in divided doses -Maximum dose: 2.4 mg orally per day in divided doses Comments: -Taking the larger portion of the oral daily dose at bedtime may minimize transient adjustment effects of dry mouth and drowsiness Transdermal patches: -Initial dose: 0.1 mg/24 hr patch applied every 7 days -Maintenance dose: If, after 1 to 2 weeks the desired reduction in blood pressure is not achieved, increase the dosage by adding another 0.1 mg/24 hr patch or changing to a larger system -Maximum dose: Doses above two 0.3 mg/24 hr patches applied every 7 days is usually not associated with additional efficacy Comments: -The transdermal patch should be applied to a hairless area of intact skin on the upper outer arm or chest. -Each new patch should be applied on a different skin site from the previous location. -If the patch loosens during 7-day wearing, the adhesive cover should be applied directly over the system to ensure good adhesion. -There have been rare reports of the need for patch changes prior to 7 days to maintain blood pressure control. -When substituting patches for the oral formulation or for other antihypertensive drugs, physicians should be aware that the antihypertensive effect of the patches may not commence until 2 to 3 days after initial application; therefore, gradual reduction of prior drug dosage is advised. Some or all previous antihypertensive treatment may have to be continued, particularly in patients with more severe forms of hypertension. Use: For hypertension, alone or in combination with other antihypertensive agents Usual Pediatric Dose for Attention Deficit Disorder: Extended release: 6 years and older: -Initial dose: 0.1 mg orally at bedtime -Titration: Increase in 0.1 mg/day increments every 7 days until desired response; doses should be administered twice daily (either split equally or with the higher split dosage given at bedtime) -Maximum dose: 0.4 mg/day in 2 divided doses Comments: -May be taken with or without food. -If a dose is missed, that dose should be skipped and take the next dose as scheduled. -Tablets should be swallowed whole, and not crushed, chewed, or broken to avoid increasing the rate of drug release. -When discontinuing therapy, taper daily dose by no more than 0.1 mg every 3 to 7 days. Use: For the treatment of attention deficit hyperactivity disorder (ADHD) as monotherapy or as adjunctive therapy to stimulant medications.   What happens if I miss a dose? Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include feeling cold, irritable, weak, drowsy, or light-headed, or having weak reflexes, pinpoint pupils, slow heartbeats, shallow breathing, or a seizure. What should I avoid while taking clonidine? Avoid drinking alcohol. It may increase certain side effects of clonidine. Avoid driving or hazardous activity until you know how clonidine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid becoming overheated or dehydrated during exercise and in hot weather. Clonidine side effects Get emergency medical help if you have signs of an allergic reaction to clonidine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: severe chest pain, shortness of breath, irregular heartbeats; a very slow heart rate; or a light-headed feeling, like you might pass out. Common clonidine side effects may include: drowsiness, dizziness; feeling tired or irritable; dry mouth; constipation, loss of appetite; or sleep problems (insomnia), nightmares. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect clonidine? Using clonidine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: other heart or blood pressure medications; an antidepressant; or any other medicine that contains clonidine. This list is not complete. Other drugs may interact with clonidine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What is clonidine? Clonidine lowers blood pressure by decreasing the levels of certain chemicals in your blood. This allows your blood vessels to relax and your heart to beat more slowly and easily. Clonidine is used to treat hypertension (high blood pressure). The Kapvay brand is used to treat attention deficit hyperactivity disorder (ADHD). Clonidine is sometimes given with other medications. Clonidine is also available as a transdermal patch worn on the skin. Do not use two forms of this medicine at the same time. Warnings Before you take clonidine, tell your doctor if you have heart disease or severe coronary artery disease, a heart rhythm disorder, slow heartbeats, low blood pressure, a history of heart attack or stroke, kidney disease, or if you have ever had an allergic reaction to a Catapres TTS transdermal skin patch. Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies. Before taking this medicine You should not take this medicine if you are allergic to clonidine. To make sure clonidine is safe for you, tell your doctor if you have: heart disease or severe coronary artery disease; a heart rhythm disorder, slow heartbeats; high or low blood pressure, or a history of fainting spells; a heart attack or stroke; pheochromocytoma (tumor of the adrenal gland); kidney disease; or if you have ever had an allergic reaction to a Catapres TTS transdermal skin patch. It is not known if clonidine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of clonidine on the baby. Clonidine may affect fertility in men or women. Pregnancy could be harder to achieve while either parent is using this medicine. If you are breastfeeding, tell your doctor if you notice somnolence, tiredness, rapid breathing, and poor feeding in the nursing baby. Catapres is not approved for use by anyone younger than 18 years old. Do not give Kapvay to a child younger than 6 years old. How should I take clonidine? Take clonidine exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Clonidine is usually taken in the morning and at bedtime. If you take different doses of this medicine at each dosing time, it may be best to take the larger dose at bedtime. Clonidine may be taken with or without food. Swallow the extended-release tablet whole and do not crush, chew, or break it. Tell your doctor if you have a planned surgery. You may have withdrawal symptoms if you stop using this medicine suddenly. Ask your doctor before stopping the medicine. Call your doctor if you are sick with vomiting. This is especially important for a child taking clonidine. If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. Store at room temperature away from moisture, heat, and light. Dosing information Usual Adult Dose for Hypertension: Oral: -Initial dose: 0.1 mg orally 2 times a day (morning and bedtime) -Titration: Increments of 0.1 mg orally per day may be made at weekly intervals to desired response -Maintenance dose: 0.2 to 0.6 mg orally per day in divided doses -Maximum dose: 2.4 mg orally per day in divided doses Comments: -Taking the larger portion of the oral daily dose at bedtime may minimize transient adjustment effects of dry mouth and drowsiness Transdermal patches: -Initial dose: 0.1 mg/24 hr patch applied every 7 days -Maintenance dose: If, after 1 to 2 weeks the desired reduction in blood pressure is not achieved, increase the dosage by adding another 0.1 mg/24 hr patch or changing to a larger system -Maximum dose: Doses above two 0.3 mg/24 hr patches applied every 7 days is usually not associated with additional efficacy Comments: -The transdermal patch should be applied to a hairless area of intact skin on the upper outer arm or chest. -Each new patch should be applied on a different skin site from the previous location. -If the patch loosens during 7-day wearing, the adhesive cover should be applied directly over the system to ensure good adhesion. -There have been rare reports of the need for patch changes prior to 7 days to maintain blood pressure control. -When substituting patches for the oral formulation or for other antihypertensive drugs, physicians should be aware that the antihypertensive effect of the patches may not commence until 2 to 3 days after initial application; therefore, gradual reduction of prior drug dosage is advised. Some or all previous antihypertensive treatment may have to be continued, particularly in patients with more severe forms of hypertension. Use: For hypertension, alone or in combination with other antihypertensive agents Usual Pediatric Dose for Attention Deficit Disorder: Extended release: 6 years and older: -Initial dose: 0.1 mg orally at bedtime -Titration: Increase in 0.1 mg/day increments every 7 days until desired response; doses should be administered twice daily (either split equally or with the higher split dosage given at bedtime) -Maximum dose: 0.4 mg/day in 2 divided doses Comments: -May be taken with or without food. -If a dose is missed, that dose should be skipped and take the next dose as scheduled. -Tablets should be swallowed whole, and not crushed, chewed, or broken to avoid increasing the rate of drug release. -When discontinuing therapy, taper daily dose by no more than 0.1 mg every 3 to 7 days. Use: For the treatment of attention deficit hyperactivity disorder (ADHD) as monotherapy or as adjunctive therapy to stimulant medications.   What happens if I miss a dose? Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include feeling cold, irritable, weak, drowsy, or light-headed, or having weak reflexes, pinpoint pupils, slow heartbeats, shallow breathing, or a seizure. What should I avoid while taking clonidine? Avoid drinking alcohol. It may increase certain side effects of clonidine. Avoid driving or hazardous activity until you know how clonidine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid becoming overheated or dehydrated during exercise and in hot weather. Clonidine side effects Get emergency medical help if you have signs of an allergic reaction to clonidine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: severe chest pain, shortness of breath, irregular heartbeats; a very slow heart rate; or a light-headed feeling, like you might pass out. Common clonidine side effects may include: drowsiness, dizziness; feeling tired or irritable; dry mouth; constipation, loss of appetite; or sleep problems (insomnia), nightmares. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect clonidine? Using clonidine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: other heart or blood pressure medications; an antidepressant; or any other medicine that contains clonidine. This list is not complete. Other drugs may interact with clonidine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What is clopidogrel? Clopidogrel is used to lower your risk of having a stroke, blood clot, or serious heart problem after you've had a heart attack, severe chest pain (angina), or circulation problems. Clopidogrel may also be used for purposes not listed in this medication guide. Warnings You should not use clopidogrel if you have any active bleeding such as a stomach ulcer or bleeding in the brain. Clopidogrel increases your risk of bleeding, which can be severe or life-threatening. Call your doctor or seek emergency medical attention if you have bleeding that will not stop, if you have blood in your urine, black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds. Do not stop taking clopidogrel without first talking to your doctor, even if you have signs of bleeding. Stopping clopidogrel may increase your risk of a heart attack or stroke. Before taking this medicine You should not use clopidogrel if you are allergic to it, or if you have: any active bleeding; or a stomach ulcer or bleeding in the brain (such as from a head injury). Tell your doctor if you have ever had: an ulcer in your stomach or intestines; or a bleeding disorder or blood clotting disorder. Clopidogrel may not work as well if you have certain genetic factors that affect the breakdown of this medicine in your body. Your doctor may perform a blood test to make sure clopidogrel is right for you. This medicine is not expected to harm an unborn baby. However, taking clopidogrel within 1 week before childbirth can cause bleeding in the mother. Tell your doctor if you are pregnant or plan to become pregnant. You should not breastfeed while using this medicine. How should I take clopidogrel? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use these medicines exactly as directed. Clopidogrel can be taken with or without food. Clopidogrel is sometimes taken together with aspirin. Take aspirin only if your doctor tells you to. Clopidogrel keeps your blood from coagulating (clotting) and can make it easier for you to bleed, even from a minor injury. Contact your doctor or seek emergency medical attention if you have any bleeding that will not stop. You may need to stop using clopidogrel for a short time before a surgery, medical procedure, or dental work. Any healthcare provider who treats you should know that you are taking clopidogrel. Do not stop taking clopidogrel without first talking to your doctor, even if you have signs of bleeding. Stopping the medicine could increase your risk of a heart attack or stroke. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause excessive bleeding. What should I avoid while taking clopidogrel? Avoid alcohol. It can increase your risk of stomach bleeding. Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth. If you also take aspirin: Ask a doctor or pharmacist before using medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to aspirin (such as salicylates, ibuprofen, ketoprofen, or naproxen). Taking these products together can increase your risk of bleeding. Clopidogrel side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Clopidogrel increases your risk of bleeding, which can be severe or life-threatening. Call your doctor or seek emergency medical attention if you have bleeding that will not stop, if you have blood in your urine, black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds. Also call your doctor at once if you have: nosebleeds, pale skin, easy bruising, purple spots under your skin or in your mouth; jaundice (yellowing of your skin or eyes); fast heartbeats, shortness of breath; headache, fever, weakness, feeling tired; little or no urination; a seizure; low blood sugar--headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or signs of a blood clot--sudden numbness or weakness, confusion, problems with vision or speech. Common side effects may include: bleeding. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Clopidogrel dosing information Usual Adult Dose for Acute Coronary Syndrome: Unstable Angina (UA)/Non-ST-Elevation Myocardial Infarction (NSTEMI): -Loading dose: 300 mg orally once -Maintenance dose: 75 mg orally once a day -Duration of therapy: Optimal duration unknown. ST-Elevation Myocardial Infarction (STEMI): -Loading dose: 300 mg orally once (OPTIONAL) -Maintenance dose: 75 mg orally once a day, with or without thrombolytics -Duration of therapy: Optimal duration unknown. Comments: -Administer this drug in combination with aspirin 75 mg to 325 mg orally once a day. -The benefit of this drug for patients who undergo primary percutaneous coronary intervention is unknown. Uses: Prevention of atherothrombotic events in patients with non-ST-segment elevation acute coronary syndrome (UA, NSTEMI, those who are to be managed medically, those who are to be managed with coronary revascularization) and STEMI. Usual Adult Dose for Ischemic Stroke: 75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease. Usual Adult Dose for Myocardial Infarction: 75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease. Usual Adult Dose for Peripheral Arterial Disease: 75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.   What other drugs will affect clopidogrel? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Tell your doctor about all your other medicines, especially: a stomach acid reducer such as omeprazole, Nexium, or Prilosec; an antidepressant such as citalopram, fluoxetine, sertraline, Cymbalta, Effexor, Lexapro, Pristiq, or Prozac; rifampin; a blood thinner--warfarin, Coumadin, Jantoven; or NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect clopidogrel, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is betamethasone and clotrimazole topical? Betamethasone is highly potent steroid that reduces itching, swelling, and redness of the skin. Clotrimazole is an antifungal medication that fights infections caused by fungus. Betamethasone and clotrimazole topical (for the skin) is a combination medicine used to treat fungal skin infections such as athlete's foot, jock itch, and ringworm. Betamethasone and clotrimazole topical may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Before taking this medicine You may not be able to use betamethasone and clotrimazole topical if you are allergic to betamethasone or clotrimazole, or if you have ever had an allergic reaction to: other steroid medicines (such as dexamethasone, fludrocortisone, hydrocortisone, prednisone, triamcinolone, and others); or other antifungal medicines (such as itraconazole, ketoconazole, miconazole, posaconazole, or voriconazole). Tell your doctor if you have ever had: a skin reaction to any steroid medicine; cataract or glaucoma; liver disease; or an adrenal gland disorder. Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes. Using highly potent steroid medicine during pregnancy may increase the risk of low birthweight in the newborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply betamethasone and clotrimazole to your chest, avoid areas that may come into contact with the baby's mouth. If you are pregnant or breastfeeding, apply this medicine to the smallest skin area and for the shortest amount of time possible to treat your condition. This medicine is not approved for use by anyone younger than 17 years old. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects. How should I use betamethasone and clotrimazole topical? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Do not take by mouth. Topical medicine is for use only on the skin. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Wash your hands before and after using betamethasone and clotrimazole, unless you are using this medicine to treat the skin on your hands. Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to. Keep your skin clean and dry to avoid further infection. Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects. Shake betamethasone and clotrimazole lotion well just before each use. If you are treating the diaper area, do not use plastic pants or tight-fitting diapers. Do not use betamethasone and clotrimazole topical to treat diaper rash. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Call your doctor if your symptoms do not improve after 1 week of using this medicine (or after 2 weeks if using the medicine on your feet). Store at room temperature away from moisture and heat. Store the lotion in an upright position.   What happens if I miss a dose? Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. High doses or long-term use of betamethasone and clotrimazole topical can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid while using betamethasone and clotrimazole topical? Avoid getting betamethasone and clotrimazole topical in your eyes, mouth, or vagina. Do not use betamethasone and clotrimazole topical to treat any skin condition that has not been checked by your doctor. Avoid using other topical steroid medications on the areas you treat with betamethasone and clotrimazole, unless your doctor tells you to. Betamethasone and clotrimazole topical side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: worsening of your skin condition; redness, warmth, swelling, oozing, or severe irritation of any treated skin; blurred vision, tunnel vision, eye pain, or seeing halos around lights; high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes. Common side effects may include: numbness, tingling, or stinging; skin dryness or rash; swelling; or new infections. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect betamethasone and clotrimazole topical? Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

What is colesevelam? Colesevelam lowers "bad" cholesterol in the blood, which is also called LDL (low-density lipoprotein) cholesterol. Lowering your LDL cholesterol may reduce your risk of hardened arteries, which can lead to heart attacks, stroke, and circulation problems. Colesevelam is used to treat high cholesterol in adults and children at least 10 years old. Colesevelam is sometimes used together with "statin" cholesterol medications such as atorvastatin, lovastatin, simvastatin, Crestor, Lipitor, Pravachol, Zocor, and others. Colesevelam is also used to improve blood sugar control in adults with type 2 diabetes mellitus. This medication is not for treating type 1 diabetes. Colesevelam may also be used for purposes not listed in this medication guide. Warnings You should not take colesevelam if you have diabetic ketoacidosis, very high triglycerides, a history of bowel obstruction, or a history of pancreatitis caused by high triglycerides. Before taking this medicine You should not take colesevelam if you are allergic to it, or if you have: very high levels of triglycerides (a type of fat) in your blood; diabetic ketoacidosis (call your doctor for treatment); a history of bowel obstruction; or a history of pancreatitis caused by high triglycerides. Colesevelam may increase your triglycerides, which can increase your risk of pancreatitis (inflammation of the pancreas). Your doctor will perform blood tests to make sure your triglycerides are not too high for you to safely use colesevelam. Colesevelam is not for use in girls who have not yet started having menstrual periods. Colesevelam should not be given to a child younger than 10 years old. Tell your doctor if you have ever had: trouble swallowing; blockage in your digestive tract (stomach or intestines); slow digestion; surgery on your stomach or intestines; or a vitamin A, D, E, or K deficiency. Tell your doctor if you are pregnant or if you become pregnant. The powder form of colesevelam may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU). How should I take colesevelam? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take colesevelam with a meal and a full glass of water or other liquid. You may have to take several tablets at a time each time you take colesevelam. Tell your doctor if you have trouble swallowing the tablet whole. Colesevelam powder must be mixed with 8 ounces of water, fruit juice, or a diet soft drink. Stir and drink this mixture right away. Add a little more water to the glass, swirl gently and drink right away. Do not change the dose or timing of any other cholesterol or diabetes medications without your doctor's advice. You will need frequent blood tests. Colesevelam is only part of a complete treatment program that may also include diet, exercise, and weight control. You may need to follow a special diet to prevent constipation while using colesevelam. Follow all instructions of your doctor or dietitian. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the medicine (with food and a full glass of water) as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking colesevelam? Avoid eating foods high in fat or cholesterol, or colesevelam will not be as effective. Colesevelam side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using colesevelam and call your doctor at once if you have: severe constipation; severe stomach pain; or pancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting. Common side effects may include: constipation; nausea; or upset stomach. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect colesevelam? Colesevelam can make it harder for your body to absorb other medicines you take, which could make those medicines less effective. If you take any of the following medicines, take them 4 hours before you take colesevelam: cyclosporine; olmesartan; phenytoin; levothyroxine or other thyroid medication; birth control pills; multivitamins; warfarin (Coumadin, Jantoven); or oral diabetes medication--chlorpropamide, glimepiride, glipizide, or glyburide, tolazamide, tolbutamide. This list is not complete and many other drugs may affect colesevelam. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is colestipol? Colestipol is a cholesterol-lowering drug. Colestipol lowers "bad" cholesterol in the blood, which is also called LDL (low-density lipoprotein) cholesterol. Lowering your LDL cholesterol may reduce your risk of hardened arteries, which can lead to heart attacks, stroke, and circulation problems. Lowering high cholesterol levels is an important part of preventing heart disease and arteriosclerosis (hardening of the arteries). Colestipol may also be used for purposes not listed in this medication guide. Warnings Do not take colestipol granules without mixing them with water or another liquid. Taking the granules dry could cause you to accidentally inhale or choke on the granules. Before taking this medicine You should not take colestipol if you are allergic to it. To make sure colestipol is safe for you, tell your doctor if you have: trouble swallowing; constipation or hemorrhoids; blockage in your intestines; a stomach or digestive disorder; liver disease; a thyroid disorder; a bleeding disorder; a history of major stomach or bowel surgery; or if you have a vitamin A, D, E, or K deficiency. Colestipol is not expected to harm an unborn baby when taken at recommended doses. However, taking colestipol can make it harder for your body to absorb certain vitamins that are needed during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while taking colestipol. Taking colestipol can make it harder for your body to absorb certain vitamins that are important if you are nursing a baby. Do not take colestipol without telling your doctor if you are breast-feeding a baby. Some forms of colestipol may contain phenylalanine. Talk to your doctor before using colestipol if you have phenylketonuria (PKU). Colestipol is not approved for use by anyone younger than 18 years old. How should I take colestipol? Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Do not crush, chew, or break colestipol tablet. Swallow it whole. Swallow only one tablet at a time. Take the tablet with a full glass of water. Call your doctor if you have have trouble swallowing the tablet, or if it feels like it gets stuck in your esophagus after you swallow it. Dissolve the colestipol granules in a small amount of water, milk, broth soup, applesauce, hot or cold cereal, or crushed fruit (such as pineapple, pears, peaches, or fruit cocktail). Stir this mixture and drink or eat all of it right away. Swallow the mixture without chewing or holding it in your mouth. Colestipol can damage your teeth if left in contact with them for too long. Do not take colestipol granules without mixing them with water, other liquid, or food. Taking the granules dry could cause you to accidentally inhale or choke on the granules. Use only the dosing scoop that comes with your supply of colestipol granules. Do not keep it for later use. The scoop may not be the right size for use with a different brand of colestipol granules. While using colestipol, you may need frequent blood tests. It may take 2 weeks to several months of using this medicine before your cholesterol levels improve. For best results, keep using the medication as directed. Colestipol is only part of a treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking colestipol? Avoid taking other medicines at the same time you take colestipol. Taking colestipol can make it harder for your body to absorb certain drugs, making them less effective. Take your other medicines at least 1 hour before or 4 hours after you take colestipol. Avoid constipation by drinking 8 to 12 full glasses (8 ounces each) every day while taking colestipol. Ask your doctor before using a laxative or stool softener. Colestipol side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: trouble swallowing; severe constipation or stomach pain; or black, bloody, or tarry stools. Common side effects may include: constipation; or hemorrhoids. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Colestipol dosing information Usual Adult Dose for Hyperlipoproteinemia: Tablets: -Initial dose: 2 g orally once or twice a day -Maintenance dose: 2 to 16 g once a day or in divided doses Comments: -Dose increases of 2 g once or twice a day should occur at 1 to 2 month intervals. -If desired therapeutic effect on low density lipoprotein (LDL) cholesterol is not obtained at a dose of 2 to 16 g per day with good compliance and acceptable side effects, combined therapy or alternate treatment should be considered. Granules: -Initial dose: 5 g (1 packet or 1 level scoop) orally once or twice a day -Maintenance dose: 5 to 30 g (1 to 6 packets or level scoops) orally once a day or in divided doses Comments: -Incremental dose increases should occur at a rate of 1 dose per day at 1 to 2 month intervals. -If desired therapeutic effect is not obtained at 1 to 6 doses per day with good compliance and acceptable side effects, combined therapy or alternate treatment should be considered. Use: For use as adjunctive treatment to diet for the reduction of elevated serum total and low-density lipoprotein (LDL) cholesterol in patients with primary hypercholesterolemia (elevated LDL) who do not respond adequately to diet   What other drugs will affect colestipol? Other drugs may interact with colestipol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What is cyclobenzaprine? Cyclobenzaprine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. Cyclobenzaprine is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury. Cyclobenzaprine may also be used for purposes not listed in this medication guide. Warnings You should not use cyclobenzaprine if you have an allergy to the medication, a certain type of thyroid disorder (hyperthyroidism), heart block, congestive heart failure, a heart rhythm disorder, or you have recently had a heart attack. Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Before taking this medicine You should not use cyclobenzaprine if you are allergic to it, or if you have: hyperthyroidism; heart block, heart rhythm disorder, congestive heart failure; or if you have recently had a heart attack. Cyclobenzaprine is not approved for use by anyone younger than 15 years old. Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Some medicines can interact with cyclobenzaprine and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications. To make sure cyclobenzaprine is safe for you, tell your doctor if you have: thyroid disease; liver disease; glaucoma; enlarged prostate; or problems with urination. It is not known whether cyclobenzaprine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk. Older adults may be more sensitive to the effects of this medicine. How should I take cyclobenzaprine? Cyclobenzaprine is usually taken taken for up to 2 or 3 weeks. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Follow your doctor's dosing instructions very carefully. Swallow the capsule whole and do not crush, chew, break, or open it. Call your doctor if your symptoms do not improve after 3 weeks, or if they get worse. Store at room temperature away from moisture, heat, and light.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of cyclobenzaprine can be fatal. Overdose symptoms may include severe drowsiness, vomiting, fast heartbeats, tremors, agitation, or hallucinations. What to avoid Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid drinking alcohol. Dangerous side effects could occur. Cyclobenzaprine side effects Get emergency medical help if you have signs of an allergic reaction to cyclobenzaprine: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have: fast or irregular heartbeats; chest pain or pressure, pain spreading to your jaw or shoulder; or sudden numbness or weakness (especially on one side of the body), slurred speech, balance problems. Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Serious side effects may be more likely in older adults. Common cyclobenzaprine side effects may include: drowsiness, tiredness; headache, dizziness; dry mouth; or upset stomach, nausea, constipation. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect cyclobenzaprine? Using cyclobenzaprine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: MAO inhibitors, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine; Any antidepressant or anxiety medications; bupropion (Zyban, for smoking cessation or Wellbutrin, for depression); meperidine; tramadol; verapamil; cold or allergy medicine that contains an antihistamine (Benadryl and others); medicine to treat Parkinson's disease; medicine to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome; medicine to treat overactive bladder; or bronchodilator asthma medication. This list is not complete. Other drugs may interact with cyclobenzaprine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is dalfampridine? Dalfampridine is used to improve walking in patients with multiple sclerosis (MS). Dalfampridine may also be used for purposes not listed in this medication guide. Warnings Dalfampridine can cause a seizure, even if you never had one before. Taking too much dalfampridine may increase your risk of seizure. Your risk may also be higher if you have kidney problems or are older than 50. Your kidney function may need to be tested before you start taking dalfampridine. Stop taking dalfampridine and call your doctor right away if you have a seizure. Before taking this medicine You should not use this medicine if you are allergic to dalfampridine or 4-aminopyridine, or if you have: moderate to severe kidney disease; or if you've ever had a seizure. Dalfampridine can cause a seizure, even if you never had one before. Your risk may also be higher if you have kidney problems or are older than 50. Tell your doctor if you have ever had: kidney disease; or if you also take a form of this medicine obtained from a compounding pharmacy (fampridine, or 4-aminopyridine). Older adults may be more sensitive to the effects of this medication. It is not known if dalfampridine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Ask a doctor if it is safe to breastfeed while using this medicine. Not approved for use by anyone younger than 18 years old. How should I take dalfampridine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Taking too much dalfampridine may increase your risk of seizure. Space your doses 12 hours apart. Do not take more than 2 tablets in 24 hours. You may take dalfampridine with or without food. Swallow the tablet whole and do not crush, chew, or break it. Breaking the pill may cause too much of the drug to be released at one time which can increase your risk of a seizure. Do not use a tablet that has been crushed or broken. Store at room temperature away from moisture and heat. Do not use past the expiration date on the label. What happens if I miss a dose? Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause confusion or seizures. What should I avoid while taking dalfampridine? Follow your doctor's instructions about any restrictions on food, beverages, or activity. Dalfampridine side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop taking dalfampridine and call your doctor right away if you have a seizure. Call your doctor at once if you have: pain or burning when you urinate; or relapse or worsening of MS symptoms. Common side effects may include: weakness, MS relapse; painful urination; dizziness, balance problems; numbness or tingling; sleep problems (insomnia); nausea, constipation, upset stomach; stuffy nose, sinus pain, sore throat; or headache, back pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Dalfampridine dosing information Usual Adult Dose for Multiple Sclerosis: Maximum dose: 10 mg orally every 12 hours Comments: -This drug may be taken with or without food. -Tablets should be swallowed whole, and not divided, crushed, chewed, or dissolved. -Patients should not take double or extra doses if a dose is missed. Use: To improve walking in adult patients with multiple sclerosis (MS) demonstrated by an increase in walking speed   What other drugs will affect dalfampridine? Tell your doctor about all your other medicines, especially: cimetidine. This list is not complete. Other drugs may affect dalfampridine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is darifenacin? Darifenacin reduces muscle spasms of the bladder and urinary tract. Darifenacin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage). Darifenacin may also be used for purposes not listed in this medication guide. Warnings You should not take darifenacin if you are have untreated or uncontrolled narrow-angle glaucoma, a stomach disorder causing delayed emptying, or if you have trouble emptying your bladder. Before taking this medicine You should not take darifenacin if you are allergic to it, or if you have: untreated or uncontrolled narrow-angle glaucoma; a stomach disorder causing delayed emptying; or if you have trouble emptying your bladder. To make sure darifenacin is safe for you, tell your doctor if you have: glaucoma; liver disease; ulcerative colitis; a blockage in your stomach or intestines; a muscle disorder such as myasthenia gravis; or if you have very little urine or a weak stream of urine. FDA pregnancy category C. It is not known whether darifenacin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using darifenacin. It is not known whether darifenacin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. How should I take darifenacin? Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Take this medicine with water. Darifenacin can be taken with or without food. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause vision problems. What should I avoid while taking darifenacin? darifenacin may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Darifenacin side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using darifenacin and call your doctor at once if you have: severe stomach pain or constipation; confusion, hallucinations; little or no urinating; pain or burning when you urinate; or signs of dehydration--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin. Common side effects may include: nausea, indigestion; constipation; headache, dizziness; dry mouth; or blurred vision. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Darifenacin dosing information Usual Adult Dose for Urinary Incontinence: Initial dose: 7.5 mg orally once a day Maintenance dose: The dosage may be increased to 15 mg orally once a day as early as 2 weeks after starting therapy Comments: -This drug may be taken with or without food. -The tablet should be swallowed whole with water and not chewed, divided, or crushed. Use: For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency Usual Adult Dose for Urinary Frequency: Initial dose: 7.5 mg orally once a day Maintenance dose: The dosage may be increased to 15 mg orally once a day as early as 2 weeks after starting therapy Comments: -This drug may be taken with or without food. -The tablet should be swallowed whole with water and not chewed, divided, or crushed. Use: For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency   What other drugs will affect darifenacin? Tell your doctor about all medicines you use, and those you start or stop using during your treatment with darifenacin, especially: clarithromycin; flecainide; thioridazine; an antidepressant--amitriptyline, clomipramine, desipramine, doxepin, imipramine, nefazodone, nortriptyline; antifungal medicine--itraconazole, ketoconazole; or HIV or AIDS medicine--nelfinavir, ritonavir. This list is not complete. Other drugs may interact with darifenacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What is desonide topical? Desonide is a steroid that helps reduce inflammation in the body. Desonide topical (for the skin) is used to treat inflammation and itching caused by eczema or skin conditions that respond to steroid medication. Desonide topical may also be used for purposes not listed in this medication guide. Warnings Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. Before taking this medicine You should not use desonide if you are allergic to it. Tell your doctor if you have ever had: any type of skin infection; diabetes; or a skin reaction to any steroid medicine. It is not known whether desonide topical will harm an unborn baby. Tell your doctor if you are pregnant. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply desonide to your chest, avoid areas that may come into contact with the baby's mouth. Do not give this medicine to a child without medical advice. Some brands or forms of this medicine are for use only in adults 18 and over. Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects. How should I use desonide topical? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth. Shake the lotion just before each use. Wash your hands after using desonide, unless you are using this medicine to treat the skin on your hands. Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to. Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects. If you are treating the diaper area, do not use plastic pants or tight-fitting diapers. This medicine is for short-term use only (such as 2 to 4 weeks). Follow your doctor's dosing instructions very carefully. You should stop using the medicine once your skin symptoms are controlled. Call your doctor if your symptoms do not improve, or if they get worse. Store at room temperature away from moisture and heat. Keep the bottle or tube tightly closed when not in use. What happens if I miss a dose? Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication. High doses or long-term use of desonide topical can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid while using desonide topical? Avoid getting desonide topical in your eyes, nose, or mouth. Do not use desonide topical to treat any skin condition that has not been checked by your doctor. Desonide topical side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: worsening of your skin condition; redness, warmth, swelling, oozing, or severe irritation of any treated skin; blurred vision, tunnel vision, eye pain, or seeing halos around lights; high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes. Steroid medicine can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine. Common side effects may include: stinging or burning of treated skin; skin irritation, redness, itching, or hardening; dry, scaly, or oily skin; swelling in your hands or feet; acne, stretch marks; or redness or crusting around your hair follicles. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Desonide topical dosing information Usual Adult Dose for Dermatitis: Cream/ointment: Apply a thin film to the affected areas two to four times per day depending on the severity of the condition Duration of therapy: 2 weeks Comments: -Treatment should be discontinued when control is achieved. -Reassessment of diagnosis may be needed, if no improvement is observed in two weeks. -This topical drug should not be used with occlusive dressings. Use: Relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses Usual Adult Dose for Eczema: Cream/ointment: Apply a thin film to the affected areas two to four times per day depending on the severity of the condition Duration of therapy: 2 weeks Comments: -Treatment should be discontinued when control is achieved. -Reassessment of diagnosis may be needed, if no improvement is observed in two weeks. -This topical drug should not be used with occlusive dressings. Use: Relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses Usual Adult Dose for Atopic Dermatitis: Foam, gel: Apply a thin film to the affected areas two times a day and rub in gently. Duration of therapy: 4 weeks Comments: -Treatment should be discontinued when control is achieved. -Reassessment of diagnosis may be needed, if no improvement is observed in four weeks. -This topical drug should not be used with occlusive dressings. Use: Treatment of mild to moderate atopic dermatitis Usual Pediatric Dose for Atopic Dermatitis: 3 months or older: Foam, gel: Apply a thin film to the affected areas two times a day and rub in gently. Duration of therapy: 4 weeks Comments: -Treatment should be discontinued when control is achieved. -Reassessment of diagnosis may be needed, if no improvement is observed in four weeks. -This topical drug should not be used with occlusive dressings. Use: Treatment of mild to moderate atopic dermatitis   What other drugs will affect desonide topical? Medicine used on the skin is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

What is desvenlafaxine? Desvenlafaxine is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant. Desvenlafaxine is used to treat major depressive disorder. Desvenlafaxine may also be used for purposes not listed in this medication guide. Warnings People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide. Do not stop using desvenlafaxine without first asking your doctor. Before taking this medicine You should not use desvenlafaxine if you are allergic to desvenlafaxine or venlafaxine (Effexor). Do not use desvenlafaxine within 7 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine. A dangerous drug interaction could occur. Tell your doctor if you also use stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with desvenlafaxine could cause a serious condition called serotonin syndrome. Tell your doctor if you have ever had: heart disease, high blood pressure, high cholesterol, or a stroke; bipolar disorder (manic depression); depression, suicidal thoughts; liver or kidney disease; glaucoma; seizures or epilepsy; sexual problems; lung or breathing problems; a bleeding or blood clotting disorder; or low levels of sodium in your blood. People with depression or mental illness may have thoughts about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Stay alert to changes in your mood or symptoms. Your family or caregivers should also watch for sudden changes in your behavior. Taking this medicine during pregnancy could harm the baby, but stopping the medicine may not be safe for you. Do not start or stop desvenlafaxine without asking your doctor. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of desvenlafaxine on the baby. Ask a doctor if it is safe to breastfeed while using this medicine. Not approved for use by anyone younger than 18 years old. How should I take desvenlafaxine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take desvenlafaxine with water at the same time each day, with or without food. Swallow the tablet whole and do not crush, chew, or break it. Your symptoms may not improve for several weeks. Your blood pressure will need to be checked often. Tell your doctor if you have any changes in sexual function, such as loss of interest in sex, trouble having an orgasm, or (in men) problems with erections or ejaculation. Some sexual problems can be treated. Do not stop using desvenlafaxine suddenly, or you could have unpleasant symptoms (such as agitation, confusion, tingling or electric shock feelings). Ask your doctor before stopping the medicine. Part of a tablet shell may appear in your stool but this will not make the medicine less effective. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking desvenlafaxine? Avoid driving or hazardous activity until you know how desvenlafaxine will affect you. Your reactions could be impaired. Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen, naproxen, Advil, Aleve, Motrin, and others. Using an NSAID with desvenlafaxine may cause you to bruise or bleed easily. Avoid drinking alcohol. Desvenlafaxine side effects Get emergency medical help if you have signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Tell your doctor right away if you have new or sudden changes in mood or behavior, including new or worse depression or anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, more active or talkative, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: a seizure; easy bruising or bleeding (nosebleeds, bleeding gums), blood in your urine or stools, coughing up blood; blurred vision, eye pain or swelling, or seeing halos around lights; cough, chest discomfort, trouble breathing; or low blood sodium--headache, confusion, problems with thinking or memory, weakness, feeling unsteady. Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Common side effects may include: dizziness, drowsiness, anxiety; increased sweating; nausea, decreased appetite, constipation; sleep problems (insomnia); or decreased sex drive, impotence, or difficulty having an orgasm. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Desvenlafaxine dosing information Usual Adult Dose for Depression: 50 mg orally once a day, with or without food Comments: -Doses of 10 to 400 mg/day were studied in clinical trials. -There is no evidence that doses greater than 50 mg per day provide additional benefit. -Side effects and discontinuations were more common at higher doses. -Efficacy in patients with major depressive disorder was established in 4 short-term and 2 maintenance studies. Use: Treatment of major depressive disorder (MDD)   What other drugs will affect desvenlafaxine? Using desvenlafaxine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially a blood thinner (warfarin, Coumadin, Jantoven) or other medicine used to prevents blood clots. Other drugs may affect desvenlafaxine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

What is dexmethylphenidate? Dexmethylphenidate is a stimulant that is used to treat attention deficit hyperactivity disorder (ADHD). Dexmethylphenidate may also be used for purposes not listed in this medication guide. Warnings Stimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect. Dexmethylphenidate may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder. Call your doctor right away if you have: signs of heart problems--chest pain, feeling light-headed or short of breath; or signs of psychosis--paranoia, aggression, new thought or behavior problems, seeing or hearing things that are not real. Dexmethylphenidate may be habit-forming. Tell your doctor if you have a history of drug or alcohol addiction. Keep the medication where others cannot get to it. Before taking this medicine You should not take dexmethylphenidate if you are allergic to dexmethylphenidate or methylphenidate (Ritalin, Concerta). Stimulants have caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have: heart problems or a congenital heart defect; high blood pressure; or a family history of heart disease or sudden death. Do not use dexmethylphenidate if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine. Tell your doctor if you also use opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with dexmethylphenidate could cause a serious condition called serotonin syndrome. Tell your doctor if you or anyone in your family has ever had: depression, mental illness, bipolar disorder, psychosis, or suicidal thoughts or actions; blood circulation problems in the hands or feet; or alcoholism or drug addiction. Becoming dependent on this medicine during pregnancy can cause premature birth or low birth weight. Tell your doctor if you are pregnant or plan to become pregnant. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of dexmethylphenidate on the baby. Ask a doctor if it is safe to breastfeed while using this medicine. Not approved for use by anyone younger than 6 years old. How should I take dexmethylphenidate? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Dexmethylphenidate may be habit-forming. Misuse can cause addiction, overdose, or death. Keep the medication where others cannot get to it. Selling or giving away this medicine is against the law. Dexmethylphenidate is usually taken twice per day, at least 4 hours apart. You may take dexmethylphenidate with or without food. Take the regular tablet twice daily, at least 4 hours apart. Take the extended-release capsule once daily in the morning. Swallow the extended-release capsule whole and do not crush, chew, break, or open it. If you cannot swallow a capsule whole, open it and mix the medicine with applesauce. Swallow the mixture right away without chewing. Your doctor will need to check your progress on a regular basis. Your heart and blood pressure may also need to be checked often. Tell your doctor if you have a planned surgery. Your treatment may also include counseling or other treatments. Store tightly closed at room temperature, away from moisture, heat, and light. Keep your medicine in a place where no one can use it improperly.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of dexmethylphenidate could be fatal. Overdose symptoms may include dry mouth, vomiting, agitation, tremor, muscle twitches, confusion, hallucinations, dilated pupils, muscle pain or weakness, fever, sweating, headache, pounding in your neck or ears, fast or pounding heartbeats, seizure (convulsions), or coma. What should I avoid while taking dexmethylphenidate? Follow your doctor's instructions about any restrictions on food, beverages, or activity. Dexmethylphenidate side effects Get emergency medical help if you have signs of an allergic reaction: fever; hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: signs of heart problems--chest pain, trouble breathing, feeling like you might pass out; signs of psychosis--hallucinations (seeing or hearing things that are not real), new thought or behavior problems, aggression, hostility, paranoia; signs of circulation problems--numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes; or penis erection that is painful or lasts 4 hours or longer. Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Dexmethylphenidate can affect growth in children. Your child's height and weight may need to be checked often. Tell your doctor if your child is not growing at a normal rate. Common side effects may include: loss of appetite; nausea, stomach pain; or fever. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect dexmethylphenidate? Tell your doctor about all your other medicines, especially: an antidepressant; or blood pressure medication. This list is not complete. Other drugs may affect dexmethylphenidate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is dextroamphetamine? Dextroamphetamine is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control. Dextroamphetamine is used to treat narcolepsy and attention deficit hyperactivity disorder (ADHD). Dextroamphetamine may also be used for purposes not listed in this medication guide. Warnings You should not use dextroamphetamine if you have glaucoma, overactive thyroid, severe agitation, moderate to severe high blood pressure, heart disease or coronary artery disease, or a history of drug or alcohol addiction. Dextroamphetamine may be habit-forming, and this medicine is a drug of abuse. Tell your doctor if you have had problems with drug or alcohol abuse. Stimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect. Do not use dextroamphetamine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Dextroamphetamine may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder. You may have blood circulation problems that can cause numbness, pain, or discoloration in your fingers or toes. Call your doctor right away if you have: signs of heart problems--chest pain, feeling light-headed or short of breath; signs of psychosis--paranoia, aggression, new behavior problems, seeing or hearing things that are not real; signs of circulation problems--unexplained wounds on your fingers or toes. Before taking this medicine You should not use dextroamphetamine if you are allergic to any stimulant medicine, or if you have: moderate to severe high blood pressure; heart disease or coronary artery disease (hardened arteries); overactive thyroid; glaucoma; severe anxiety, tension, or agitation (stimulant medicine can make these symptoms worse); or a history of drug or alcohol addiction. Do not use dextroamphetamine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. Some medicines can interact with dextroamphetamine and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications. Stimulants have caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have: heart problems or a congenital heart defect; high blood pressure; or a family history of heart disease or sudden death. To make sure this medicine is safe for you, tell your doctor if you or anyone in your family has ever had: depression, mental illness, bipolar disorder, psychosis, or suicidal thoughts or actions; motor tics (muscle twitches) or Tourette's syndrome; seizures or epilepsy; an abnormal brain wave test (EEG); or blood circulation problems in the hands or feet. Taking dextroamphetamine during pregnancy can cause premature birth, low birth weight, or withdrawal symptoms in the newborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Dextroamphetamine can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine. Dextroamphetamine is not approved for use by anyone younger than 3 years old. Dextroamphetamine extended-release capsules are not for use in children younger than 6 years old. How should I take dextroamphetamine? Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take dextroamphetamine in larger or smaller amounts or for longer than recommended. Dextroamphetamine may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law. Dextroamphetamine is sometimes taken 2 or 3 times per day. Extended-release dextroamphetamine is taken only once per day. Follow your doctor's dosing instructions very carefully. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Do not crush, chew, break, or open an extended-release capsule. Swallow it whole. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. While using this medicine, your doctor will need to check your progress at regular visits. Tell any doctor who treats you that you are using this medicine. Store at room temperature away from moisture, heat, and light. Keep track of your medicine. Dextroamphetamine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. Detailed Dextroamphetamine dosage information What happens if I miss a dose? Take the missed dose as soon as you remember, but not late in the day. Skip the missed dose if it is almost evening. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of dextroamphetamine can be fatal. Overdose symptoms may include restlessness, tremor, muscle twitches, rapid breathing, confusion, hallucinations, panic, aggressiveness, muscle pain or weakness, and dark colored urine. These symptoms may be followed by depression and tiredness. Other overdose symptoms include nausea, vomiting, diarrhea, stomach pain, uneven heartbeats, feeling light-headed, fainting, seizure (convulsions), or coma. What should I avoid while taking dextroamphetamine? Dextroamphetamine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid drinking fruit juices or taking vitamin C at the same time you take dextroamphetamine. These can make your body absorb less of the medicine. Dextroamphetamine side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: signs of heart problems--chest pain, trouble breathing, feeling like you might pass out; signs of psychosis--hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia; signs of circulation problems--numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes; a seizure (convulsions); muscle twitches (tics); or changes in your vision. Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Dextroamphetamine can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using dextroamphetamine. Common side effects may include: dry mouth, upset stomach, loss of appetite, weight loss; headache, dizziness; tremors, fast heartbeats; or sleep problems (insomnia). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect dextroamphetamine? Many drugs can interact with dextroamphetamine. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially: an antacid; an antidepressant; blood pressure medication; or seizure medicine. This list is not complete and many other drugs can interact with dextroamphetamine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Warning This medicine has a risk of abuse and misuse. Use this medicine (dextroamphetamine and amphetamine extended-release capsules) only as you were told by your doctor. Tell your doctor if you have ever abused or been addicted to any drugs or alcohol. Uses of Dextroamphetamine and Amphetamine Extended-Release Capsules: It is used to treat attention deficit problems with hyperactivity. It may be given to you for other reasons. Talk with the doctor. What do I need to tell my doctor BEFORE I take Dextroamphetamine and Amphetamine Extended-Release Capsules? If you have an allergy to dextroamphetamine, amphetamine, or any other part of this medicine (dextroamphetamine and amphetamine extended-release capsules). If you are allergic to this medicine (dextroamphetamine and amphetamine extended-release capsules); any part of this medicine (dextroamphetamine and amphetamine extended-release capsules); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you or a family member have any of these health problems: Blood vessel disease, high blood pressure, heart structure problems or other heart problems, or Tourette's syndrome or tics. If you have any of these health problems: Glaucoma, agitation, anxiety, or overactive thyroid. If you have ever had any of these health problems: Drug abuse or stroke. If you have kidney disease. If you are taking acetazolamide. If you are taking sodium bicarbonate. If you have taken certain drugs for depression or Parkinson's disease in the last 14 days. This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen. If you are taking any of these drugs: Linezolid or methylene blue. If you are breast-feeding. Do not breast-feed while you take this medicine (dextroamphetamine and amphetamine extended-release capsules). This is not a list of all drugs or health problems that interact with this medicine (dextroamphetamine and amphetamine extended-release capsules). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (dextroamphetamine and amphetamine extended-release capsules) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. What are some things I need to know or do while I take Dextroamphetamine and Amphetamine Extended-Release Capsules? Tell all of your health care providers that you take this medicine (dextroamphetamine and amphetamine extended-release capsules). This includes your doctors, nurses, pharmacists, and dentists. Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine (dextroamphetamine and amphetamine extended-release capsules) affects you. If you have been taking this medicine (dextroamphetamine and amphetamine extended-release capsules) for a long time or at high doses, it may not work as well and you may need higher doses to get the same effect. This is known as tolerance. Call your doctor if this medicine (dextroamphetamine and amphetamine extended-release capsules) stops working well. Do not take more than ordered. This medicine may be habit-forming with long-term use. If you have been taking this medicine (dextroamphetamine and amphetamine extended-release capsules) for many weeks, talk with your doctor before stopping. You may want to slowly stop this medicine (dextroamphetamine and amphetamine extended-release capsules). You may need to have some heart tests before starting this medicine (dextroamphetamine and amphetamine extended-release capsules). If you have questions, talk with your doctor. This medicine may cause high blood pressure. Check blood pressure and heart rate as the doctor has told you. Have blood work checked as you have been told by the doctor. Talk with the doctor. This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take this medicine (dextroamphetamine and amphetamine extended-release capsules). Do not take antacids with this medicine (dextroamphetamine and amphetamine extended-release capsules). Talk with your doctor before using OTC products that may raise blood pressure. These include cough or cold drugs, diet pills, stimulants, ibuprofen or like products, and some natural products or aids. New or worse behavior and mood changes like change in thinking, anger, and hallucinations have happened with this medicine (dextroamphetamine and amphetamine extended-release capsules). Tell your doctor if you or a family member have any mental or mood problems like depression or bipolar illness, or if a family member has committed suicide. Call your doctor right away if you have hallucinations; change in the way you act; or signs of mood changes like depression, thoughts of suicide, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life. A severe and sometimes deadly problem called serotonin syndrome may happen if you take this medicine (dextroamphetamine and amphetamine extended-release capsules) with certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; severe diarrhea, upset stomach, or throwing up; or severe headache. This medicine may affect growth in children and teens in some cases. They may need regular growth checks. Talk with the doctor. Different brands of this medicine (dextroamphetamine and amphetamine extended-release capsules) may be for use in different ages of children. Talk with the doctor before giving this medicine (dextroamphetamine and amphetamine extended-release capsules) to a child. Avoid drinking alcohol while taking this medicine (dextroamphetamine and amphetamine extended-release capsules). Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine (dextroamphetamine and amphetamine extended-release capsules) while you are pregnant. How is this medicine (Dextroamphetamine and Amphetamine Extended-Release Capsules) best taken? Use this medicine (dextroamphetamine and amphetamine extended-release capsules) as ordered by your doctor. Read all information given to you. Follow all instructions closely. Take with or without food but take the same way each time. Always take with food or always take on an empty stomach. Take in the morning. Swallow whole. Do not chew, break, or crush. You may sprinkle contents of capsule on applesauce. Do not chew. After mixing, take your dose right away. Do not store for future use. What do I do if I miss a dose? Skip the missed dose and go back to your normal time. Do not take it later in the day. Detailed Amphetamine / dextroamphetamine dosage information What are some side effects that I need to call my doctor about right away? WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Not able to get or keep an erection. Change in sex interest. Seizures. Trouble controlling body movements. Restlessness. Change in eyesight. For males, erections (hard penis) that happen often or that last a long time. Change in color of hands or feet from pale to blue or red. Numbness, pain, tingling, or cold feeling of the hands or feet. Any sores or wounds on the fingers or toes. Muscle pain or weakness, dark urine, or trouble passing urine. Pain when passing urine. Heart attacks, strokes, and sudden deaths have happened in adults taking this medicine (dextroamphetamine and amphetamine extended-release capsules). Sudden deaths have also happened in children with some heart problems or heart defects. Call your doctor right away if you have a fast, slow, or abnormal heartbeat; weakness on 1 side of the body; trouble speaking or thinking; change in balance; drooping on 1 side of the face; change in eyesight; chest pain or pressure; shortness of breath; or severe dizziness or passing out. Amphetamine / dextroamphetamine side effects (more detail) What are some other side effects of Dextroamphetamine and Amphetamine Extended-Release Capsules? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Feeling nervous and excitable. Headache. Not hungry. Trouble sleeping. Diarrhea or constipation. Stomach pain. Feeling dizzy, tired, or weak. Dry mouth. Bad taste in your mouth. Weight loss. Upset stomach or throwing up. These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch. If OVERDOSE is suspected: If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened. How do I store and/or throw out Dextroamphetamine and Amphetamine Extended-Release Capsules? Store at room temperature. Protect from light. Store in a dry place. Do not store in a bathroom. Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets. Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area. Consumer information use If your symptoms or health problems do not get better or if they become worse, call your doctor. Do not share your drugs with others and do not take anyone else's drugs. This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine (dextroamphetamine and amphetamine extended-release capsules) is refilled. If you have any questions about this medicine (dextroamphetamine and amphetamine extended-release capsules), please talk with the doctor, pharmacist, or other health care provider. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.