What is prednisone? Prednisone is a corticosteroid. It prevents the release of substances in the body that cause inflammation. It also suppresses the immune system. Prednisone is used as an anti-inflammatory or an immunosuppressant medication. Prednisone treats many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. Warnings Prednisone treats many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. You should avoid taking prednisone if you have a fungal infection that requires oral antifungals. Topical antifungals may not be an issue, but always let your doctor know what medicines you’re taking before starting this medicine. Steroid medication can weaken your immune system, making it easier for you to get an infection. Avoid being near people who are sick or have infections. Do not receive a "live" vaccine while using prednisone. Call your doctor at once if you have shortness of breath, severe pain in your upper stomach, bloody or tarry stools, severe depression, changes in personality or behavior, vision problems, or eye pain. You should not stop using prednisone suddenly. Follow your doctor's instructions about tapering your dose. Before taking this medicine You should not use this medication if you are allergic to prednisone, or if you have a fungal infection that requires oral antifungal treatment. Steroid medication can weaken your immune system, making it easier for you to get an infection or worsening an infection you already have or have recently had. Tell your doctor about any illness or infection you have had within the past several weeks. To make sure prednisone is safe for you, tell your doctor if you have: any illness that causes diarrhea; liver disease (such as cirrhosis); kidney disease; heart disease, high blood pressure, low levels of potassium in your blood; a thyroid disorder; diabetes; a history of malaria; tuberculosis; osteoporosis; glaucoma, cataracts, or herpes infection of the eyes; stomach ulcers, ulcerative colitis, or a history of stomach bleeding; a muscle disorder such as myasthenia gravis; or depression or mental illness. Long-term use of steroids may lead to bone loss (osteoporosis), especially if you smoke, if you do not exercise, if you do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis. Talk with your doctor about your risk of osteoporosis. Prednisone can cause low birth weight or birth defects if you take the medicine during your first trimester. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Use effective birth control. Prednisone can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Steroids can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medicine. How should I take prednisone? Take prednisone exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Take prednisone with food. Your dosage needs may change if you have any unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Do not change your medication dose or schedule without your doctor's advice. Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. Do not crush, chew, or break a delayed-release tablet. Swallow it whole. While using this medicine, you may need frequent blood tests at your doctor's office. Your blood pressure may also need to be checked. This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using this medicine. You should not stop using prednisone suddenly. Follow your doctor's instructions about tapering your dose. Wear a medical alert tag or carry an ID card stating that you take prednisone. Any medical care provider who treats you should know that you are using a steroid. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of prednisone is not expected to produce life threatening symptoms. However, long term use of high steroid doses can lead to symptoms such as thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex. What should I avoid? Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chicken pox or measles. These conditions can be serious or even fatal in people who are using a steroid. Do not receive a "live" vaccine while using this medicine. Prednisone may increase your risk of harmful effects from a live vaccine. Live vaccines include measles, mumps, rubella (MMR), rotavirus, yellow fever, varicella (chickenpox), one type of the typhoid vaccine and nasal flu (influenza) vaccine. Avoid drinking alcohol while you are taking prednisone. Prednisone side effects Get emergency medical help if you have any of these signs of an allergic reaction to prednisone: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: blurred vision, eye pain, or seeing halos around lights; swelling, rapid weight gain, feeling short of breath; severe depression, feelings of extreme happiness or sadness, changes in personality or behavior, seizure (convulsions); bloody or tarry stools, coughing up blood; pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate); low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure). Other common prednisone side effects may include: sleep problems (insomnia), mood changes; increased appetite, gradual weight gain; acne, increased sweating, dry skin, thinning skin, bruising or discoloration; slow wound healing; headache, dizziness, spinning sensation; nausea, stomach pain, bloating; or changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect prednisone? Many drugs can interact with prednisone. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with prednisone, especially: amphotericin B; cyclosporine; digoxin, digitalis; St. John's wort; an antibiotic such as clarithromycin or telithromycin; antifungal medication such as itraconazole, ketoconazole, posaconazole, voriconazole; birth control pills and other hormones; a blood thinner such as warfarin, Coumadin; a diuretic or "water pill"; the hepatitis C medications boceprevir or telaprevir; HIV or AIDS medicine such as atazanavir, delavirdine, efavirenz, fosamprenavir, indinavir, nelfinavir, nevirapine, ritonavir, saquinavir; insulin or diabetes medications you take by mouth; a non-steroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others; seizure medications such as carbamazepine, fosphenytoin, oxcarbazepine, phenobarbital, phenytoin, primidone; or the tuberculosis medications isoniazid, rifabutin, rifapentine, or rifampin. This list is not complete and many other drugs can interact with prednisone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

What is pregabalin? Pregabalin is an anti-epileptic drug, also called an anticonvulsant. It works by slowing down impulses in the brain that cause seizures. Pregabalin also affects chemicals in the brain that send pain signals across the nervous system. Pregabalin is used to treat pain caused by fibromyalgia, or nerve pain in people with diabetes (diabetic neuropathy), herpes zoster (post-herpetic neuralgia), or spinal cord injury. Pregabalin is also used with other medications to treat partial onset seizures in adults and children who are at least 1 month old. Pregabalin may also be used for purposes not listed in this medication guide. Warnings Pregabalin can cause a severe allergic reaction. Stop taking pregabalin and seek emergency medical help if you have hives or blisters on your skin, trouble breathing, or swelling in your face, mouth, or throat. Some people have thoughts about suicide while taking pregabalin. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor. If you have diabetes or heart problems, call your doctor if you have weight gain or swelling in your hands or feet while taking pregabalin. Do not stop using pregabalin suddenly, even if you feel fine. Stopping suddenly may cause withdrawal symptoms. Before taking this medicine You should not use pregabalin if you are allergic to it. Tell your doctor if you have ever had: lung disease, such as chronic obstructive pulmonary disease (COPD); a mood disorder, depression, or suicidal thoughts; heart problems (especially congestive heart failure); a bleeding disorder, or low levels of platelets in your blood; kidney disease (or if you are on dialysis); diabetes (unless you are taking pregabalin to treat diabetic neuropathy); drug or alcohol addiction; or a severe allergic reaction (angioedema). Do not give this medicine to a child without medical advice. Pregabalin is not approved for use by anyone younger than 18 years old to treat nerve pain caused by fibromyalgia, diabetes, herpes zoster, or spinal cord injury. Pregabalin is not approved for seizures in anyone younger than 1 month old. Some people have thoughts about suicide while taking pregabalin. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Seizure control is very important during pregnancy, and having a seizure could harm both mother and baby. Do not start or stop taking pregabalin without your doctor's advice, and tell your doctor right away if you become pregnant. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of pregabalin on the baby. Pregabalin can decrease sperm count and may affect fertility in men (your ability to have children). In animal studies, pregabalin also caused birth defects in the offspring of males treated with this medicine. However, it is not known whether these effects would occur in humans. Ask your doctor about your risk. You should not breastfeed while using pregabalin. How should I take pregabalin? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Take the medicine at the same time each day, with or without food. Swallow an extended-release tablet whole and do not crush, chew, or break it. Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Call your doctor if your symptoms do not improve, or if they get worse. Do not stop using pregabalin suddenly, even if you feel fine. Stopping suddenly may cause increased seizures or unpleasant withdrawal symptoms. Follow your doctor's instructions about tapering your dose for at least 1 week before stopping completely. In case of emergency, wear or carry medical identification to let others know you take seizure medication. Store at room temperature away from moisture, heat, and light.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking pregabalin? Avoid drinking alcohol. It may increase certain side effects of pregabalin. Avoid driving or hazardous activity until you know how pregabalin will affect you. Your reactions could be impaired. Pregabalin side effects Pregabalin can cause a severe allergic reaction. Stop taking this medicine and get emergency medical help if you have: hives or blisters on your skin; difficult breathing; swelling of your face, lips, tongue, or throat. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: weak or shallow breathing; blue-colored skin, lips, fingers, and toes; confusion, extreme drowsiness or weakness; vision problems; skin sores (if you have diabetes); easy bruising, unusual bleeding; swelling in your hands or feet, rapid weight gain (especially if you have diabetes or heart problems); or unexplained muscle pain, tenderness, or weakness (especially if you also have fever or don't feel well). Pregabalin can cause life-threatening breathing problems. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up. Breathing problems may be more likely in older adults or in people with COPD. If you have diabetes, tell your doctor right away if you have any new sores or other skin problems. Common side effects may include: dizziness, drowsiness; swelling in your hands and feet; trouble concentrating; increased appetite; weight gain; dry mouth; or blurred vision. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect pregabalin? Using pregabalin with other drugs that slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, cold or allergy medicine, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: oral diabetes medicine--pioglitazone, rosiglitazone; or an ACE inhibitor--benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril. This list is not complete. Other drugs may affect pregabalin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is Prevalite? Prevalite helps reduce cholesterol (fatty acids) in the blood. High cholesterol is associated with an increased risk of heart disease and atherosclerosis (clogged arteries). Prevalite is used to lower high levels of cholesterol in the blood, especially low-density lipoprotein (LDL) ("bad" cholesterol). Prevalite powder is also used to treat itching caused by a blockage in the bile ducts of the gallbladder. Prevalite may also be used for purposes not listed in this medication guide. Warnings You should not use Prevalite if you have a blockage in your stomach or intestines. Wait at least 4 to 6 hours after taking Prevalite before you take any other medications. Before taking this medicine You should not use Prevalite if you are allergic to it, or if you have: a blockage in your digestive tract (stomach or intestines). To make sure Prevalite is safe for you, tell your doctor if you have: chronic constipation; a thyroid disorder; diabetes; kidney disease; liver disease; or coronary artery disease (clogged arteries). This medicine may contain phenylalanine. Talk to your doctor before using Prevalite if you have phenylketonuria (PKU). Taking Prevalite can make it harder for your body to absorb certain vitamins. Your doctor may recommend you take a vitamin supplement. You may have an even greater need for vitamin supplements during pregnancy or while you are breast-feeding a baby. Follow your doctor's instructions about taking vitamin supplements during treatment with Prevalite. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. How should I take Prevalite? Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use Prevalite in larger or smaller amounts or for longer than recommended. Although Prevalite is usually taken once or twice per day, this medicine may be taken up to 6 times per day. Carefully follow your doctor's dosing instructions. Mix the Prevalite powder with at least 2 to 3 ounces of water or other non-carbonated beverage. You may also mix the powder with a brothy soup, crushed pineapple, or applesauce. Measure the powder using the scoop provided with your medication. Do not use any other scoop or measuring cup to measure your this medicine dose. Prevalite works best if you take it with meals. However, your dosing schedule may depend on when you need to take any other medications. This medicine should not be taken within 1 hour after or 4 hours before you take other medications. Use Prevalite regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. Prevalite can affect the surfaces of your teeth. Sipping the this medicine/liquid mixture slowly or holding the liquid in your mouth for too long may result in tooth discoloration, enamel erosion, or tooth decay. Be sure to brush your teeth regularly while you are using this medicine. Drink extra fluids to prevent constipation while you are taking Prevalite. While using Prevalite, you may need frequent blood tests. Prevalite is only part of a complete program of treatment that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe stomach pain or constipation. What should I avoid while taking Prevalite? Avoid taking other medications at the same time you take Prevalite. Wait at least 4 to 6 hours after taking this medicine before you take any other medications. Prevalite side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: ongoing or worsening constipation; severe stomach pain; blood in your urine; black, bloody, or tarry stools; or easy bruising, unusual bleeding. Side effects such as constipation may be more likely in older adults. Common side effects may include: mild constipation, diarrhea; stomach pain, nausea, loss of appetite; bloating or gas; irritation of your tongue; or itching or irritation around your rectal area. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect Prevalite? Tell your doctor about all your current medicines and any you start or stop using, especially: birth control pills or hormone replacement therapy; digoxin (digitalis); a diuretic or "water pill"; penicillin G; phenobarbital; phenylbutazone; propranolol; spironolactone; tetracycline; thyroid medication such as levothyroxine (Synthroid and others); or warfarin (Coumadin, Jantoven). This list is not complete. Other drugs may interact with cholestyramine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

What is primidone? Primidone is an anticonvulsant medicine that is used to control seizures. Primidone may also be used for purposes not listed in this medication guide. Warnings Some people have thoughts about suicide while taking primidone. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor. Do not stop using primidone suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Before taking this medicine You should not use primidone if you are allergic to primidone or phenobarbital, or if you have: porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system). Tell your doctor if you have ever had: depression; a mood disorder; or suicidal thoughts or actions. Some people have thoughts about suicide while taking primidone. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Do not start or stop taking seizure medication during pregnancy without your doctor's advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of primidone on the baby. Be sure to tell the doctor who delivers your baby about your primidone use. Both you and the baby may need to receive medications to prevent excessive bleeding during delivery and just after birth. Stop breast-feeding if you notice unusual drowsiness in the nursing baby. Talk with your doctor about how best to feed your baby while taking primidone. How should I take primidone? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. If you are switching to primidone from another seizure medication, you may need to start taking primidone only at bedtime. Follow your doctor's instructions. Do not stop using primidone suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose. It may take several weeks before you receive the full benefit of taking primidone. Your doctor will determine how long to treat you with this medicine. If you use this medicine long-term, you may need frequent medical tests. Store primidone at room temperature away from moisture, light, and heat. In case of emergency, wear or carry medical identification to let others know you take seizure medication.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking primidone? Avoid driving or hazardous activity until you know how primidone will affect you. Your reactions could be impaired. Drinking alcohol with this medicine can increase side effects. Primidone side effects Get emergency medical help if you have signs of an allergic reaction: hives, mouth sores, skin rash with blistering and peeling; difficult breathing; swelling of your face, lips, tongue, or throat. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: unusual thoughts or behavior; loss of balance or coordination; fever, chills, sore throat; easy bruising or bleeding; or pale skin, unusual tiredness. Common side effects may include: dizziness, drowsiness, spinning sensation; problems with balance or muscle movement; nausea, vomiting, loss of appetite; feeling tired or irritable; blurred vision; rash; or impotence, sexual problems. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect primidone? Using primidone with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Other drugs may affect primidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is prochlorperazine? Prochlorperazine rectal is used to control severe nausea and vomiting in adults. Prochlorperazine may also be used for purposes not listed in this medication guide. Warnings You should not use prochlorperazine if you have recently used alcohol, sedatives, tranquilizers, or opioid medication. Prochlorperazine is not approved for use in older adults with dementia-related psychosis. Do not give prochlorperazine to a child younger than 2 years old or weighing less than 20 pounds. Before taking this medicine You should not use prochlorperazine if you are allergic to it, or if you have recently used alcohol, sedatives, tranquilizers, or opioid medication. Do not give this medicine to a child younger than 2 years old or weighing less than 20 pounds. Talk with your doctor before giving this medicine to a child of any age who has been ill with a fever or flu symptoms. Prochlorperazine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. Tell your doctor if you have ever had: heart disease; cancer; bone marrow suppression; an infectious disease such as chickenpox, measles, stomach flu, or an infection of the central nervous system; an enlarged prostate or urination problems; a seizure; glaucoma; or pheochromocytoma (tumor of the adrenal gland). Tell your doctor if you will be exposed to extreme heat or cold, or to insecticide poisons while you are using prochlorperazine. Tell your doctor if you are pregnant. Using prochlorperazine rectal in the last 3 months of pregnancy may cause breathing problems, feeding problems, or withdrawal symptoms in the newborn. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. How should I use rectal prochlorperazine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Do not take a rectal suppository by mouth. It is for use only in your rectum. Wash your hands before and after inserting the suppository. Remove the wrapper before inserting the suppository. Avoid handling the suppository too long or it will melt. Lie on your back with your knees up toward your chest. Gently insert the suppository into your rectum about 1 inch, pointed tip first. Stay lying down for a few minutes while the suppository melts. You should feel little or no discomfort. Avoid using the bathroom for at least an hour. Try to empty your bowel and bladder just before using the prochlorperazine suppository. If you need surgery or a medical procedure, tell the doctor you currently use prochlorperazine. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause dry mouth, constipation, bloating or stomach cramps, extreme drowsiness or feeling restless and agitated, changes in heart rate, fever, and fainting. What should I avoid while using rectal prochlorperazine? Avoid driving or operating machinery until you know how prochlorperazine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Drinking alcohol with this medicine can cause side effects. Rectal prochlorperazine side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. High doses or long-term use of prochlorperazine can cause a serious movement disorder that may not be reversible. The longer you use prochlorperazine, the more likely you are to develop this disorder, especially if you are a diabetic or an older adult. Call your doctor at once if you have: uncontrolled muscle movements in your arms, legs, or face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); a light-headed feeling, like you might pass out; agitation; jaundice (yellowing of the skin or eyes); slow heart rate, weak pulse, fainting, slow breathing; fever, chills, sore throat, mouth sores; new or worsening symptoms of lupus--joint pain, and a skin rash on your cheeks or arms that worsens in sunlight; or severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out. Side effects such as dry mouth, constipation, confusion, and tremors may be more likely in older adults. Common side effects may include: dizziness, drowsiness; feeling restless or jittery; blurred vision; constipation; breast swelling or discharge, a missed menstrual period; sleep problems (insomnia); or swelling in your hands or feet.  

What is progesterone? Progesterone is a naturally occurring hormone important for the regulation of ovulation and menstruation. Progesterone is produced in high amounts in females by the ovaries. It is also produced in smaller amounts by the adrenal glands both males and females. Progesterone is used to cause menstrual periods in women who have not yet reached menopause but are not having periods due to a lack of progesterone in the body. It is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy. Progesterone should not be used to prevent heart disease or dementia, because this medicine may actually increase your risk of developing these conditions. Warnings Do not use progesterone without telling your doctor if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment. You should not use progesterone if you have: abnormal vaginal bleeding, a history of breast cancer, liver disease, or if you have recently had a heart attack, stroke, or blood clot. Progesterone should not be used to prevent heart disease or dementia, because this medicine may actually increase your risk of developing these conditions. Using progesterone can increase your risk of blood clots, stroke, heart attack, or breast cancer. Some forms of this medication may contain peanut oil. Do not use this medicine without telling your doctor if you have a peanut allergy. Before taking this medicine You should not use progesterone if you are allergic to it, or if you have: abnormal vaginal bleeding that a doctor has not checked; a history of breast cancer; liver disease; a peanut allergy; if you are pregnant; if you have had a stroke, heart attack, or blood clot within the past year; or if you have recently had an incomplete miscarriage or "missed" abortion. Using progesterone can increase your risk of blood clots, stroke, heart attack, or breast cancer. To make sure this medicine is safe for you, tell your doctor if you have: heart disease, circulation problems; migraines; asthma; kidney disease; seizures or epilepsy; a history of depression; or risk factors for coronary artery disease (such as high blood pressure, diabetes, lupus, high cholesterol, family history of coronary artery disease, smoking, being overweight). Do not use progesterone if you are pregnant. It could harm the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Progesterone can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby. How should I use progesterone? Use progesterone exactly as it was prescribed for you. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Take the capsule with a full glass of water. It is best to take the medicine at night because this medicine can make you dizzy or drowsy. Apply progesterone cream to the skin as directed by your doctor. Progesterone is sometimes used for only a short time, such as 10 to 12 days during each menstrual cycle. Follow your doctor's dosing instructions very carefully. Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using progesterone. If you need surgery or medical tests or if you will be on bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using this medicine. Store at room temperature away from moisture, heat, and light.   What happens if I miss a dose? Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. Call your doctor if you miss more than one dose of this medication. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using progesterone? Progesterone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Progesterone side effects Get emergency medical help if you have signs of an allergic reaction to progesterone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: unusual vaginal bleeding; pain or burning when you urinate; a breast lump; sudden vision problems, severe headache or pain behind your eyes; symptoms of depression (sleep problems, weakness, mood changes); severe dizziness or drowsiness, spinning sensation, confusion, shortness of breath; heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); signs of a stroke - sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with speech or balance; signs of a blood clot in the lung - chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or signs of a blood clot in your leg - pain, swelling, warmth, or redness in one or both legs. Common progesterone side effects may include: drowsiness, dizziness; breast pain; mood changes; headache; constipation, diarrhea, heartburn; bloating, swelling in your hands or feet; joint pain; hot flashes; or vaginal discharge. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect progesterone? There may be other drugs that can interact with progesterone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

What is promethazine? Promethazine is in a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing the actions of chemicals in your brain. Promethazine also acts as an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body. Promethazine is used to treat allergy symptoms such as itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes. It also prevents motion sickness, and treats nausea and vomiting or pain after surgery. It is also used as a sedative or sleep aid. Promethazine is not for use in treating symptoms of asthma, pneumonia, or other lower respiratory tract infections. Warnings Stop using promethazine and call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous side effects. Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in a child in very young children. Carefully follow your doctor's instructions when giving this medicine to a child of any age. Promethazine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which can increase some of the side effects of promethazine. There are many other medicines that can interact with promethazine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you. Before taking this medicine Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in very young children. Carefully follow your doctor's instructions when giving this medicine to a child of any age. You should not take this medicine if you are allergic to promethazine or to similar medicines such as chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, thioridazine, or trifluperazine. To make sure promethazine is safe for you, tell your doctor if you have: asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder; a sulfite allergy; a history of seizures; a weak immune system (bone marrow depression); glaucoma; enlarged prostate or problems with urination; stomach ulcer or obstruction; heart disease or high blood pressure; liver disease; adrenal gland tumor (pheochromocytoma); low levels of calcium in your blood (hypocalcemia); or if you have ever had a serious side effect while using promethazine or any other phenothiazine. It is not known whether promethazine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine. It is not known whether promethazine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine. How should I take promethazine? Take promethazine exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Promethazine is often taken at bedtime or before meals. For motion sickness, promethazine is usually started within 1 hour before traveling. When used for surgery, promethazine is usually taken the night before the surgery. How often you take this medicine and the timing of your dose will depend on the condition being treated. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. If a child is using this medicine, tell your doctor if the child has any changes in weight. Promethazine doses are based on weight in children, and any changes may affect your child's dose. Call your doctor if your symptoms do not improve, or if they get worse while using promethazine. This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using promethazine. Store at room temperature away from moisture, heat, and light.   What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions). What to avoid This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Drinking alcohol can increase certain side effects of promethazine. Avoid exposure to sunlight or tanning beds. Promethazine can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Promethazine side effects Get emergency medical help if you have any signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using promethazine and call your doctor at once if you have: severe drowsiness, weak or shallow breathing; a light-headed feeling, like you might pass out; confusion, agitation, hallucinations, nightmares; seizure (convulsions); fast or slow heartbeats; jaundice (yellowing of the skin or eyes); uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); easy bruising or bleeding (nosebleeds, bleeding gums); sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing; or severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out. Side effects such as confusion and severe drowsiness may be more likely in older adults. Common promethazine side effects may include: drowsiness, dizziness; ringing in your ears; double vision; feeling nervous; dry mouth; or tired feeling, sleep problems (insomnia). This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect promethazine? Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can interact with promethazine and cause medical problems or increase side effects. Tell your doctor if you regularly use any of these medicines. Also tell your doctor if you are using any of the following medicines: lithium (Eskalith, Lithobid); atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop); blood pressure medication such as guanadrel (Hylorel), guanethidine (Ismelin), propranolol (Inderal), and others; a blood thinner such as warfarin (Coumadin); bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva); bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol), solifenacin (Vesicare), and others; an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam); or medicines to treat Parkinson's disease, restless leg syndrome, or pituitary gland tumor (prolactinoma); or medicine to treat stomach ulcer or irritable bowel syndrome, such as dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), mepenzolate (Cantil), or propantheline (Pro-Banthine). This list is not complete and there are many other medicines that can interact with promethazine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

What is propafenone? Propafenone is a Class IC anti-arrhythmic that affects the way your heart beats. Propafenone is used in certain situations to prevent serious heart rhythm disorders. Propafenone may also be used for purposes not listed in this medication guide. Warnings You should not use propafenone if you have heart failure, Brugada syndrome, sick sinus syndrome, AV block (without a pacemaker), severe low blood pressure, very slow heartbeats, a severe electrolyte imbalance, shortness of breath, or if you recently had a heart attack. Propafenone may cause a new or worsening heartbeat pattern. Call your doctor at once if you have fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness. Before taking this medicine You should not use propafenone if you are allergic to it, or if you have: heart failure, or if you have recently had a heart attack; a genetic heart condition called Brugada syndrome; a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker); severe low blood pressure, or history of slow heart beats that have caused you to faint; a severe or uncontrolled electrolyte imbalance; or wheezing or shortness of breath. Tell your doctor if you have ever had: a breathing disorder; liver or kidney disease; lupus; myasthenia gravis; or an abnormal blood test called Antinuclear Antibody Test or ANA. Tell your doctor if you have a pacemaker or defibrillator. These devices may need to be re-programmed while you are taking propafenone. Tell your doctor if you are pregnant or breast-feeding. propafenone may affect fertility (ability to have children) in men. Talk with your doctor if you have concerns about this risk. How should I take propafenone? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. You may take propafenone with or without food. You may have very low blood pressure while taking this medication. Call your doctor if you are sick with vomiting or diarrhea, extreme thirst, loss of appetite, or if you are sweating more than usual. You may need frequent blood tests. Your heart function may also need to be checked with an electrocardiograph or ECG (sometimes called an EKG), before and during treatment with propafenone. Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. Detailed Propafenone dosage information What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking propafenone? Grapefruit may interact with propafenone and lead to unwanted side effects. Avoid the use of grapefruit products. Propafenone side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Propafenone may cause a new or worsening heartbeat pattern. Call your doctor at once if you have fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out) Also call your doctor at once if you have: shortness of breath (even with mild exertion); swelling in your arms or legs; sudden weight gain; or fever, chills, sore throat. Common side effects may include: irregular heartbeats; nausea, vomiting, constipation; headache, dizziness, tiredness; or unusual or unpleasant taste in your mouth. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Propafenone side effects (more detail) What other drugs will affect propafenone? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Propafenone can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Many drugs can affect propafenone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is propranolol? Propranolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins). Propranolol is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions. It is also used to treat or prevent heart attack, and to reduce the severity and frequency of migraine headaches. Hemangeol (propranolol oral liquid 4.28 milligrams) is given to infants 5 weeks to 1 year old to treat a genetic condition called infantile hemangiomas. Hemangiomas are caused by blood vessels grouping together in an abnormal way. These blood vessels form benign (non-cancerous) growths that can develop into ulcers or red marks on the skin. Hemangiomas can also cause more serious complications inside the body (in the liver, brain, or digestive system). Warnings You should not use propranolol if you have asthma, very slow heart beats, or a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker). Babies who weigh less than 4.5 pounds should not be given Hemangeol oral liquid. Before taking this medicine You should not use propranolol if you are allergic to it, or if you have: asthma; history of slow heart beats that have caused you to faint; severe heart failure (that required you to be in the hospital); or a serious heart condition such as "sick sinus syndrome" or heart block (2nd or 3rd degree, unless you have a pacemaker). You should not use Hemangeol if you have pheochromocytoma (tumor of the adrenal gland). propranolol also should not be used in babies who weigh less than 4.4 pounds. To make sure propranolol is safe for you, tell your doctor if you have ever had: slow heartbeats, congestive heart failure; bronchitis, emphysema, or other breathing disorders; diabetes (propranolol can make it harder for you to tell when you have low blood sugar); liver or kidney disease; a thyroid disorder; pheochromocytoma (tumor of the adrenal gland); problems with circulation (such as Raynaud's syndrome); or if you smoke. Tell your doctor if you are pregnant or breastfeeding. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include feeling light-headed or restless, tremors, fast or slow heartbeats, and trouble breathing. What should I avoid while taking propranolol? Avoid drinking alcohol. It may increase your blood levels of propranolol. Propranolol side effects Get emergency medical help if you have signs of an allergic reaction to propranolol (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Call your doctor at once if you have: slow or uneven heartbeats; a light-headed feeling, like you might pass out; wheezing or trouble breathing; sudden weakness, vision problems, or loss of coordination (especially in a child with hemangioma that affects the face or head); cold feeling in your hands and feet; depression, confusion, hallucinations; heart problems - swelling, rapid weight gain, feeling short of breath; low blood sugar - headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or low blood sugar in a baby - pale skin, blue or purple skin, sweating, fussiness, crying, not wanting to eat, feeling cold, drowsiness, weak or shallow breathing (breathing may stop for short periods), seizure (convulsions), or loss of consciousness.

What is propranolol? Propranolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins). Propranolol is used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions. It is also used to treat or prevent heart attack, and to reduce the severity and frequency of migraine headaches. Hemangeol (propranolol oral liquid 4.28 milligrams) is given to infants 5 weeks to 1 year old to treat a genetic condition called infantile hemangiomas. Hemangiomas are caused by blood vessels grouping together in an abnormal way. These blood vessels form benign (non-cancerous) growths that can develop into ulcers or red marks on the skin. Hemangiomas can also cause more serious complications inside the body (in the liver, brain, or digestive system). Warnings You should not use propranolol if you have asthma, very slow heart beats, or a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker). Babies who weigh less than 4.5 pounds should not be given Hemangeol oral liquid. Before taking this medicine You should not use propranolol if you are allergic to it, or if you have: asthma; history of slow heart beats that have caused you to faint; severe heart failure (that required you to be in the hospital); or a serious heart condition such as "sick sinus syndrome" or heart block (2nd or 3rd degree, unless you have a pacemaker). You should not use Hemangeol if you have pheochromocytoma (tumor of the adrenal gland). propranolol also should not be used in babies who weigh less than 4.4 pounds. To make sure propranolol is safe for you, tell your doctor if you have ever had: slow heartbeats, congestive heart failure; bronchitis, emphysema, or other breathing disorders; diabetes (propranolol can make it harder for you to tell when you have low blood sugar); liver or kidney disease; a thyroid disorder; pheochromocytoma (tumor of the adrenal gland); problems with circulation (such as Raynaud's syndrome); or if you smoke. Tell your doctor if you are pregnant or breastfeeding. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include feeling light-headed or restless, tremors, fast or slow heartbeats, and trouble breathing. What should I avoid while taking propranolol? Avoid drinking alcohol. It may increase your blood levels of propranolol. Propranolol side effects Get emergency medical help if you have signs of an allergic reaction to propranolol (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Call your doctor at once if you have: slow or uneven heartbeats; a light-headed feeling, like you might pass out; wheezing or trouble breathing; sudden weakness, vision problems, or loss of coordination (especially in a child with hemangioma that affects the face or head); cold feeling in your hands and feet; depression, confusion, hallucinations; heart problems - swelling, rapid weight gain, feeling short of breath; low blood sugar - headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or low blood sugar in a baby - pale skin, blue or purple skin, sweating, fussiness, crying, not wanting to eat, feeling cold, drowsiness, weak or shallow breathing (breathing may stop for short periods), seizure (convulsions), or loss of consciousness.

What is propylthiouracil? Propylthiouracil is used to treat hyperthyroidism (overactive thyroid), Graves' disease, or toxic goiter (enlarged thyroid). propylthiouracil is sometimes given to control symptoms just before you undergo thyroid surgery or treatment with radioactive iodine. Propylthiouracil may also be used for purposes not listed in this medication guide. Warnings Propylthiouracil can cause serious or fatal liver problems. Stop taking this medicine and call your doctor right away if you have upper stomach pain, nausea, vomiting, loss of appetite, fever, itching, tiredness, dark urine, clay-colored stools, or yellowing of your skin or eyes. Before taking this medicine You should not use propylthiouracil if you are allergic to it. Tell your doctor if you have ever had liver problems. In very rare cases, propylthiouracil has caused liver failure and death in pregnant women during the second or third trimester of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant. Tell your doctor if you are breastfeeding. Propylthiouracil may cause liver failure in children, but is sometimes used in children who cannot be treated with other medications. Do not give propylthiouracil to a child without your doctor's advice. How should I take propylthiouracil? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Propylthiouracil is usually taken 3 times per day. You will need frequent blood tests to check your thyroid. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, sore throat). Tell your doctor if you have a planned surgery. Store at room temperature away from moisture and heat. Detailed Propylthiouracil dosage information What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include fever, chills, itching, upset stomach, nausea, vomiting, swelling, headache, or joint pain. What should I avoid while taking propylthiouracil? Avoid driving or hazardous activity until you know how propylthiouracil will affect you. Your reactions could be impaired. Propylthiouracil side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Propylthiouracil can cause liver damage (especially during the first 6 months of treatment). Liver failure can be fatal or may require a liver transplant. Stop taking propylthiouracil and call your doctor right away if you have signs of liver damage: nausea, vomiting, upper stomach pain; itching; fever, tiredness; loss of appetite; dark urine, clay-colored stools; or jaundice (yellowing of the skin or eyes). Also call your doctor at once if you have: fever, chills, sore throat, mouth sores, feeling light-headed; unusual bleeding; purple or red discoloration of your skin; skin rash, skin pain or swelling; pink or dark urine, foamy urine, little or no urination; shortness of breath, or if you cough up blood; or new or worsening symptoms of lupus--joint pain, and a skin rash on your cheeks or arms that worsens in sunlight. Common side effects may include: nausea, vomiting, stomach pain; itching or tingling, nerve pain; joint or muscle pain; swollen glands; headache, drowsiness, dizziness; swelling in your hands or feet; decreased sense of taste; or hair loss. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.  

What is pyridostigmine? Pyridostigmine affects chemicals in the body that are involved in the communication between nerve impulses and muscle movement. Pyridostigmine is used to treat the symptoms of myasthenia gravis. It is also used in military personnel who have been exposed to nerve gas. Pyridostigmine may also be used for purposes not listed in this medication guide. Warnings You should not use pyridostigmine if you you have a bladder or bowel obstruction. Before taking this medicine You should not use pyridostigmine if you are allergic to it, or if you have a bladder or bowel obstruction. To make sure you can safely take pyridostigmine, tell your doctor if you have any of these other conditions: asthma; or kidney disease. FDA pregnancy category C. It is not known whether pyridostigmine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using pyridostigmine. It is not known whether pyridostigmine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Pyridostigmine is not approved for use by anyone younger than 18 years old. How should I take pyridostigmine? Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Take this medicine with food or milk if it upsets your stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. The amount and timing of this medicine is extremely important to the success of your treatment. Carefully follow your doctor's instructions about how much medicine to take and when to take it. Your doctor may occasionally change your dose to make sure you get the best results. You may be asked to keep a daily record of when you took each dose and how long the effects lasted. This will help your doctor determine if your dose needs to be adjusted. If you need surgery, tell the surgeon ahead of time that you are using pyridostigmine. You may need to stop using the medicine for a short time. Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the canister of moisture-absorbing preservative that comes with this medicine.   What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, diarrhea, stomach cramps, sweating, blurred vision, drooling, and weak or shallow breathing. Worsening muscle weakness, or no change in your myasthenia gravis symptoms, may also be signs of overdose. What should I avoid while taking pyridostigmine? This medication may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Drinking alcohol can increase certain side effects of pyridostigmine. Pyridostigmine side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using pyridostigmine and call your doctor at once if you have any of these serious side effects: extreme muscle weakness; loss of movement in any part of your body; weak or shallow breathing; slurred speech, vision problems; or worsening or no improvement in your symptoms of myasthenia gravis. Common side effects may include: stomach pain, nausea, vomiting, diarrhea; muscle cramps, twitching; sweating, increased salivation; cough with mucus; rash; or blurred vision. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect pyridostigmine? Other drugs may interact with pyridostigmine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What is quetiapine? Quetiapine is an antipsychotic medicine that is used to treat schizophrenia in adults and children who are at least 13 years old. Quetiapine is used to treat bipolar disorder (manic depression) in adults and children who are at least 10 years old. Quetiapine is also used together with antidepressant medications to treat major depressive disorder in adults. Quetiapine may also be used for purposes not listed in this medication guide. Warnings Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor. Quetiapine is not approved for use in older adults with dementia-related psychosis. Before taking this medicine You should not use quetiapine if you are allergic to it. Quetiapine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. Quetiapine is not approved for use by anyone younger than 10 years old. Tell your doctor if you have ever had: liver disease; heart problems; high or low blood pressure; low white blood cell (WBC) counts; abnormal thyroid tests or prolactin levels; constipation or urination problems; an enlarged prostate; a seizure; glaucoma or cataracts; high cholesterol or triglycerides; diabetes (in you or a family member); or trouble swallowing. Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Taking antipsychotic medicine in the last 3 months of pregnancy may cause withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking quetiapine without your doctor's advice. quetiapine may temporarily affect fertility (your ability to have children) in women. You should not breastfeed while you are using quetiapine. How should I take quetiapine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. High doses or long-term use of quetiapine can cause a serious movement disorder that may not be reversible. The longer you use quetiapine, the more likely you are to develop this disorder, especially if you are an older adult. Symptoms of this disorder include tremors or other uncontrollable muscle movements. You may take Seroquel with or without food. You should take Seroquel XR without food or with a light meal. Swallow the tablet whole and do not crush, chew, or break it. Quetiapine may cause you to have high blood sugar (hyperglycemia). If you are diabetic, check your blood sugar levels on a regular basis. Drink plenty of liquids while you are taking quetiapine. Blood pressure may need to be checked often in a child or teenager taking quetiapine. You should not stop using quetiapine suddenly. Stopping suddenly may make your condition worse. This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use quetiapine. Store at room temperature away from moisture and heat. Detailed Quetiapine dosage information What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of quetiapine can be fatal. What should I avoid while taking quetiapine? Avoid drinking alcohol. Dangerous side effects could occur. Avoid driving or hazardous activity until you know how quetiapine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid becoming overheated or dehydrated during exercise and in hot weather. You may be more prone to heat stroke. Quetiapine side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); mask-like appearance of the face, trouble swallowing, problems with speech; a light-headed feeling, like you might pass out; severe constipation; painful or difficult urination; blurred vision, tunnel vision, eye pain, or seeing halos around lights; severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, fainting; high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or low white blood cell counts--fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing, feeling light-headed. Common side effects may include: speech problems; dizziness, drowsiness, tiredness; lack of energy; fast heartbeats; stuffy nose; increased appetite, weight gain; upset stomach, vomiting, constipation; dry mouth; or problems moving. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Quetiapine side effects (more detail) What other drugs will affect quetiapine? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Quetiapine can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Many drugs can affect quetiapine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is quetiapine? Quetiapine is an antipsychotic medicine that is used to treat schizophrenia in adults and children who are at least 13 years old. Quetiapine is used to treat bipolar disorder (manic depression) in adults and children who are at least 10 years old. Quetiapine is also used together with antidepressant medications to treat major depressive disorder in adults. Quetiapine may also be used for purposes not listed in this medication guide. Warnings Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor. Quetiapine is not approved for use in older adults with dementia-related psychosis. Before taking this medicine You should not use quetiapine if you are allergic to it. Quetiapine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. Quetiapine is not approved for use by anyone younger than 10 years old. Tell your doctor if you have ever had: liver disease; heart problems; high or low blood pressure; low white blood cell (WBC) counts; abnormal thyroid tests or prolactin levels; constipation or urination problems; an enlarged prostate; a seizure; glaucoma or cataracts; high cholesterol or triglycerides; diabetes (in you or a family member); or trouble swallowing. Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms. Taking antipsychotic medicine in the last 3 months of pregnancy may cause withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking quetiapine without your doctor's advice. quetiapine may temporarily affect fertility (your ability to have children) in women. You should not breastfeed while you are using quetiapine. How should I take quetiapine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. High doses or long-term use of quetiapine can cause a serious movement disorder that may not be reversible. The longer you use quetiapine, the more likely you are to develop this disorder, especially if you are an older adult. Symptoms of this disorder include tremors or other uncontrollable muscle movements. You may take Seroquel with or without food. You should take Seroquel XR without food or with a light meal. Swallow the tablet whole and do not crush, chew, or break it. Quetiapine may cause you to have high blood sugar (hyperglycemia). If you are diabetic, check your blood sugar levels on a regular basis. Drink plenty of liquids while you are taking quetiapine. Blood pressure may need to be checked often in a child or teenager taking quetiapine. You should not stop using quetiapine suddenly. Stopping suddenly may make your condition worse. This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use quetiapine. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of quetiapine can be fatal. What should I avoid while taking quetiapine? Avoid drinking alcohol. Dangerous side effects could occur. Avoid driving or hazardous activity until you know how quetiapine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid becoming overheated or dehydrated during exercise and in hot weather. You may be more prone to heat stroke. Quetiapine side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); mask-like appearance of the face, trouble swallowing, problems with speech; a light-headed feeling, like you might pass out; severe constipation; painful or difficult urination; blurred vision, tunnel vision, eye pain, or seeing halos around lights; severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, fainting; high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or low white blood cell counts--fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing, feeling light-headed. Common side effects may include: speech problems; dizziness, drowsiness, tiredness; lack of energy; fast heartbeats; stuffy nose; increased appetite, weight gain; upset stomach, vomiting, constipation; dry mouth; or problems moving. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect quetiapine? Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Quetiapine can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. Many drugs can affect quetiapine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

What is quinapril? Quinapril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Quinapril is used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack. Quinapril is also used together with other medications to treat heart failure. Quinapril may also be used for purposes not listed in this medication guide. Warnings Do not use if you are pregnant. If you become pregnant, stop taking quinapril and tell your doctor right away. You should not use quinapril if you have ever had angioedema. Do not take quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto). If you have diabetes, do not use quinapril together with any medication that contains aliskiren (a blood pressure medicine). Before taking this medicine You should not use quinapril if you are allergic to it, or if: you have a history of angioedema; you recently took a heart medicine called sacubitril; or if you are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, ramipril, or trandolapril. Do not take quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto). If you have diabetes, do not use quinapril together with any medication that contains aliskiren (a blood pressure medicine). You may also need to avoid taking quinapril with aliskiren if you have kidney disease. Tell your doctor if you have ever had: kidney disease (or if you are on dialysis); liver disease; a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis; heart disease or congestive heart failure (unless you are taking quinapril for this condition); or if you are on a low-salt diet. Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Quinapril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. Quinapril is not approved for use by anyone younger than 18 years old. How should I take quinapril? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Your blood pressure will need to be checked often. Your kidney or liver function may also need to be tested. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking quinapril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure. If you need surgery, tell the surgeon ahead of time that you are using quinapril. You may need to stop using the medicine for a short time. If you are being treated for high blood pressure, keep using quinapril even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking quinapril? Drinking alcohol can further lower your blood pressure and may increase certain side effects of quinapril. Do not use salt substitutes or potassium supplements while taking quinapril, unless your doctor has told you to. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Quinapril side effects Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; fast or pounding heartbeats, fluttering in your chest; little or no urination; pain or burning when you urinate; jaundice (yellowing of the skin or eyes); numbness, tingling, or burning pain in your hands or feet; fever, chills, cold or flu symptoms; high potassium--nausea, chest pain, irregular heartbeats, loss of movement; or low sodium--headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady. Common side effects may include: headache; cough; or dizziness, tired feeling. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Quinapril dosing information Usual Adult Dose for Hypertension: Initial dose: 10 or 20 mg orally once a day in patients not on diuretics Maintenance dose: 20 to 80 mg orally per day, administered as a single dose or in two equally divided doses Use: -Treatment of hypertension Usual Adult Dose for Congestive Heart Failure: Initial dose: 5 mg orally twice a day Maintenance dose: 20 to 40 mg orally per day administered in two equally divided doses Comments: -This dose may improve symptoms of heart failure, but increases in exercise duration have generally required higher doses. -If the initial dosage is well tolerated, patients should then be titrated at weekly intervals until an effective dose. Use: -Management of heart failure as adjunctive therapy when added to conventional therapy including diuretics and/or digitalis Usual Geriatric Dose for Congestive Heart Failure: 10 mg orally once a day Comments: Dose should be titrated the same way as for other adult patients. Uses: -Treatment of hypertension -Management of heart failure as adjunctive therapy when added to conventional therapy including diuretics and/or digitalis Usual Geriatric Dose for Hypertension: 10 mg orally once a day Comments: Dose should be titrated the same way as for other adult patients. Uses: -Treatment of hypertension -Management of heart failure as adjunctive therapy when added to conventional therapy including diuretics and/or digitalis   What other drugs will affect quinapril? Tell your doctor about all your other medicines, especially: lithium; a diuretic or "water pill"; gold injections to treat arthritis; or NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect quinapril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is hydrochlorothiazide and quinapril? Hydrochlorothiazide is a thiazide diuretic (water pill). Quinapril is in an ACE inhibitor (ACE stands for angiotensin converting enzyme). Hydrochlorothiazide and quinapril is a combination medicine used to treat hypertension (high blood pressure). Lowering blood pressure may lower your risk of a stroke or heart attack. Hydrochlorothiazide and quinapril may also be used for purposes not listed in this medication guide. Warnings Do not use if you are pregnant. If you become pregnant, stop taking hydrochlorothiazide and quinapril and tell your doctor right away. You should not use this medicine if you have ever had angioedema, if you are unable to urinate, or if you are allergic to sulfa drugs or to any ACE inhibitor. Do not take hydrochlorothiazide and quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto). If you have diabetes, do not use hydrochlorothiazide and quinapril together with any medication that contains aliskiren (a blood pressure medicine). Before taking this medicine You should not use this medicine if you are allergic to hydrochlorothiazide or quinapril, or if: you have a history of angioedema; you are unable to urinate; you recently took a heart medicine called sacubitril; or you have ever had a severe allergic reaction to any ACE inhibitor (benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, trandolapril). Do not take hydrochlorothiazide and quinapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto). If you have diabetes, do not use hydrochlorothiazide and quinapril together with any medication that contains aliskiren (a blood pressure medicine). You may also need to avoid taking hydrochlorothiazide and quinapril with aliskiren if you have kidney disease. Tell your doctor if you have ever had: kidney disease (or if you are on dialysis); cirrhosis or other liver disease; glaucoma; congestive heart failure; gout; lupus; an allergy to sulfa drugs or penicillin; or if you are on a low-salt diet. Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Quinapril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. You should not breastfeed while using hydrochlorothiazide and quinapril. Hydrochlorothiazide and quinapril is not approved for use by anyone younger than 18 years old. How should I take hydrochlorothiazide and quinapril? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking hydrochlorothiazide and quinapril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure. Your blood pressure will need to be checked often, and you may need occasional blood tests. If you need surgery, tell your surgeon you currently use this medicine. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Store at room temperature away from moisture, heat, and light. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking hydrochlorothiazide and quinapril? Hydrochlorothiazide may increase your risk of skin cancer. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Your doctor may want you to have skin examinations on a regular basis. Drinking alcohol can further lower your blood pressure and may increase certain side effects of hydrochlorothiazide and quinapril. Do not use salt substitutes or potassium supplements while taking this medicine, unless your doctor has told you to. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough. Hydrochlorothiazide and quinapril side effects Get emergency medical help if you have signs of an allergic reaction (hives, severe stomach pain, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). You may be more likely to have an allergic reaction if you are African-American. Call your doctor at once if you have: a light-headed feeling, like you might pass out; blurred vision, tunnel vision, eye pain, or seeing halos around lights; swelling, weight gain, shortness of breath; sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, trouble swallowing; high potassium--nausea, tingly feeling, chest pain, irregular heartbeats, loss of movement; low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling; or low levels of sodium--headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady. Common side effects may include: cough; headache, dizziness; tired feeling; or muscle pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Hydrochlorothiazide and quinapril dosing information Usual Adult Dose for Hypertension: Hydrochlorothiazide 12.5 to 25 mg-quinapril 10 to 20 mg orally once a day Comments: -The initial dosage of hydrochlorothiazide-quinapril should be based on the patient requirements for each drug individually.   What other drugs will affect hydrochlorothiazide and quinapril? Tell your doctor about all your other medicines, especially: any other blood pressure medication; lithium; everolimus, sirolimus, temsirolimus; an antibiotic--demeclocycline, doxycycline, minocycline, eravacycline, omadacycline, sarecycline, tetracycline; or NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect hydrochlorothiazide and quinapril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is rabeprazole? Rabeprazole is used short-term to treat symptoms of gastroesophageal reflux disease (GERD) in adults and children who are at least 1 year old. Rabeprazole is used only in adults to treat conditions involving excessive stomach acid, such as Zollinger-Ellison syndrome. Rabeprazole is also used in adults to promote healing of duodenal ulcers or erosive esophagitis (damage to your esophagus caused by stomach acid). Rabeprazole may also be given with an antibiotic to prevent duodenal ulcer caused by infection with Helicobacter pylori (H. pylori). Rabeprazole is not for immediate relief of heartburn symptoms. Rabeprazole may also be used for purposes not listed in this medication guide. Warnings Rabeprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine. Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it. Rabeprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight. You may be more likely to have a broken bone while taking rabeprazole long term or more than once per day. Before taking this medicine Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed. You should not use this medicine if you are allergic to rabeprazole or: if you also take any medicine that contains rilpivirine (Edurant, Complera, Juluca, Odefsey); if you had breathing problems, kidney problems, or a severe allergic reaction after taking rabeprazole in the past; or if you are also allergic to medicines like rabeprazole, such as esomeprazole, lansoprazole, omeprazole, pantoprazole , Nexium, Prevacid, Prilosec, Protonix, and others. Tell your doctor if you have ever had: liver disease; osteoporosis or low bone mineral density (osteopenia); lupus (an autoimmune disorder); or low levels of magnesium in your blood. You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy. Tell your doctor if you are pregnant or breastfeeding. Do not give this medicine to a child without medical advice. Certain forms and strengths of rabeprazole should not be given to a child younger than 12 years old. How should I take rabeprazole? Rabeprazole is usually taken once per day. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Rabeprazole is for short-term use only, usually 4 to 8 weeks. Your doctor may recommend a second course of treatment if you need additional healing time. AcipHex Sprinkle should not be given to a child younger than 1 year old. Take rabeprazole with a full glass of water. If you take rabeprazole to treat duodenal ulcers, take the medicine after a meal. If you take rabeprazole to prevent ulcers caused by Helicobacter pylori, take the medicine with food. If you take rabeprazole for any other condition, you may take the medicine with or without food. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions. Swallow the tablet whole and do not crush, chew, or break it. Do not swallow a delayed-release capsule (AcipHex Sprinkle) whole. Open it and sprinkle the medicine into a spoonful of soft food such as applesauce, yogurt, or baby food made from fruit or vegetable. You may also mix the medicine with apple juice, Pedialyte, or infant formula. Swallow the mixture right away without chewing. Do not save it for later use. This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using rabeprazole. Some conditions are treated with a combination of rabeprazole and antibiotics. Use all medications as directed. Take your medicines for the full prescribed length of time, even if your symptoms quickly improve. Call your doctor if your symptoms do not improve, or if they get worse while using rabeprazole. Store at room temperature away from moisture and heat.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking rabeprazole? rabeprazole can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine. Rabeprazole side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody; sudden pain or trouble moving your hip, wrist, or back; seizure (convulsions); kidney problems--fever, rash, nausea, loss of appetite, joint pain, urinating less than usual, blood in your urine, swelling, rapid weight gain; new or worsening symptoms of lupus--joint pain, and a skin rash on your cheeks or arms that worsens in sunlight; low magnesium--dizziness, fast or irregular heart rate, tremors (shaking) or jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet, cough or choking feeling; or signs of bleeding (if you also take warfarin)--headaches, dizziness, weakness; pain or swelling; bruising, unusual bleeding (nosebleeds, bleeding gums); red or pink urine; heavy menstrual flow; bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or any bleeding that will not stop. Taking rabeprazole long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk. If you use rabeprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it. Common side effects may include: infection; pain; sore throat; headache; nausea, vomiting; gas, diarrhea, constipation; or stomach pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect rabeprazole? Tell your doctor about all your current medicines. Many drugs can affect rabeprazole, especially: an antibiotic such as clarithromycin or amoxicillin; digoxin; a diuretic or "water pill"; methotrexate; or warfarin (Coumadin, Jantoven). This list is not complete and many other drugs may affect rabeprazole. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is raloxifene? Raloxifene is used to treat osteoporosis in postmenopausal women. Raloxifene is not for use in men. Raloxifene may also be used for purposes not listed in this medication guide. Warnings raloxifene may increase your risk of a blood clot in your leg, your lung, or your eye. You should not take raloxifene if you have ever had this type of blood clot. Raloxifene can also increase your risk of a stroke, which can be fatal. This risk is highest if you have certain risk factors (such as smoking, having heart problems or high blood pressure, or if you have ever had a heart attack or a stroke). Although this medicine is for use only in postmenopausal women, you should not take raloxifene if you are pregnant or breastfeeding. Before taking this medicine This medicine may increase your risk of a blood clot in your leg, your lung, or your eye. You should not take raloxifene if you have ever had this type of blood clot. This medicine is for use only in women who can no longer get pregnant. Raloxifene can harm an unborn baby. Do not use if you are pregnant or may become pregnant. Do not breastfeed while taking raloxifene. Raloxifene can increase your risk of a stroke, which can be fatal. Tell your doctor if you have ever had: heart problems, irregular heartbeats; a heart attack or stroke, including "mini-stroke"; high blood pressure; cancer; or if you smoke. Tell your doctor if you have ever had: a blood clot; high triglycerides caused by using estrogen; liver or kidney disease; endometriosis; abnormal vaginal bleeding; or if you have not gone through menopause. How should I take raloxifene? Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take the medicine at the same time each day, with or without food. If you need major surgery or will be on long-term bed rest, you will need to stop taking raloxifene at least 3 days ahead of time. You may not be able to restart the medicine until you are active again. Tell any doctor or surgeon who treats you that you take raloxifene. Raloxifene is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin D supplements. Follow your doctor's instructions very closely. Your doctor should check your progress on a regular basis. Self-examine your breasts for lumps on a monthly basis, and have regular mammograms. Store at room temperature away from moisture and heat. What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking raloxifene? If you take calcium supplements, do not take more than your doctor has prescribed. Taking more calcium than recommended will not provide extra protection for your bones, and may cause serious side effects including kidney stones. Avoid sitting still for long periods of time during travel while you are taking raloxifene. Raloxifene side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using raloxifene and call your doctor at once if you have: swelling, tenderness, or other changes in your breasts; signs of a stroke--sudden numbness or weakness (especially on one side of the body), slurred speech, vision problems; signs of a blood clot in the lung--chest pain, trouble breathing, coughing up blood; or signs of a blood clot deep in the body--swelling, warmth, or redness in an arm or leg. Common side effects may include: hot flashes; leg cramps; swelling in your hands, feet, or ankles; joint pain; flu symptoms; or increased sweating. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Raloxifene dosing information Usual Adult Dose for Osteoporosis: 60 mg orally per day Comments: -For treatment or prevention of osteoporosis, advise patients to add supplemental calcium and/or vitamin D if daily intake is inadequate. -When this drug is used to reduce the risk of invasive breast cancer, the optimum duration of treatment is not known. Uses: -Treatment and prevention of osteoporosis in postmenopausal women. -Reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and/or at high risk of invasive breast cancer. Usual Adult Dose for Prevention of Osteoporosis: 60 mg orally per day Comments: -For treatment or prevention of osteoporosis, advise patients to add supplemental calcium and/or vitamin D if daily intake is inadequate. -When this drug is used to reduce the risk of invasive breast cancer, the optimum duration of treatment is not known. Uses: -Treatment and prevention of osteoporosis in postmenopausal women. -Reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and/or at high risk of invasive breast cancer. Usual Adult Dose for Prevention of Breast Cancer: 60 mg orally per day Comments: -For treatment or prevention of osteoporosis, advise patients to add supplemental calcium and/or vitamin D if daily intake is inadequate. -When this drug is used to reduce the risk of invasive breast cancer, the optimum duration of treatment is not known. Uses: -Treatment and prevention of osteoporosis in postmenopausal women. -Reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and/or at high risk of invasive breast cancer.   What other drugs will affect raloxifene? Tell your doctor about all your other medicines, especially: cholestyramine; warfarin (Coumadin, Jantoven); or birth control pills or hormone replacement therapy. This list is not complete. Other drugs may affect raloxifene, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is ramipril? Ramipril (Altace) is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Ramipril is used to treat high blood pressure (hypertension) or congestive heart failure, and to improve survival after a heart attack. Ramipril may also be used for purposes not listed in this medication guide. Warnings Do not use ramipril if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. You should not use ramipril if you have ever had angioedema. Do not take this medicine within 36 hours before or after taking medicine that contains sacubatril (such as Entresto). If you have diabetes, do not use ramipril together with any medication that contains aliskiren (such as Tekturna or Tekamlo). Before taking this medicine You should not use ramipril if you are allergic to it, or if: you have a history of angioedema; you recently took a heart medicine called sacubatril; or if you are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, or trandolapril. Do not take ramipril within 36 hours before or after taking medicine that contains sacubatril (such as Entresto). If you have diabetes, do not use ramipril together with any medication that contains aliskiren (such as Tekturna or Tekamlo). You may also need to avoid taking ramipril with aliskiren if you have kidney disease. To make sure this medicine is safe for you, tell your doctor if you have ever had: kidney disease (or if you are on dialysis); liver disease; a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis; or if you are also taking telmisartan (Micardis). Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Ramipril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control. It is not known whether ramipril passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine. How should I take ramipril? Take ramipril exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended. Ramipril can be taken with or without food. Swallow the tablet whole. You may open the capsule and sprinkle the medicine into a half-cup (4 ounces) of water, apple juice, or applesauce to make swallowing easier. Swallow without chewing. You may store the mixture for up to 24 hours at room temperature, or up to 48 hours in a refrigerator. Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking ramipril. This can lead to very low blood pressure, electrolyte disorders, or kidney failure. Your blood pressure will need to be checked often, and you may need frequent blood tests to check your potassium levels. Drink plenty of water each day while you are taking this medication. If you need surgery, tell the surgeon ahead of time that you are using this medicine. If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.   What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid? Do not use salt substitutes or potassium supplements while taking ramipril, unless your doctor has told you to. Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of ramipril. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Ramipril side effects Get emergency medical help if you have any signs of an allergic reaction to ramipril: hives; severe stomach pain; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; jaundice (yellowing of your skin or eyes); little or no urination; fever, chills, sore throat, cold or flu symptoms; or high potassium - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement. Common ramipril side effects may include: headache; cough; or dizziness, weakness, tired feeling. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is ranolazine? Ranolazine is used to treat chronic angina (chest pain). Ranolazine is not for use during an acute (emergency) attack of angina. Ranolazine may also be used for purposes not listed in this medication guide. Warnings You should not take ranolazine if you have cirrhosis of the liver. Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together. Before taking this medicine You should not take ranolazine if you are allergic to it, or if you have: cirrhosis of the liver. Many drugs can interact and cause dangerous effects. Some drugs should not be used together with ranolazine. Your doctor may change your treatment plan if you also use: clarithromycin; nefazodone; St. John's wort; antifungal medicine--itraconazole, ketoconazole; HIV or AIDS medicine--indinavir, lopinavir/ritonavir, nelfinavir, ritonavir, saquinavir; seizure medicine--carbamazepine, phenobarbital, phenytoin; or tuberculosis medicine--rifabutin, rifampin, rifapentine. Tell your doctor if you have ever had: long QT syndrome (in you or a family member); liver disease; or kidney disease. Tell your doctor if you are pregnant or breastfeeding. How should I take ranolazine? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. You may take ranolazine with or without food. Swallow the tablet whole and do not crush, chew, or break it. Chronic angina is often treated with a combination of drugs. Use all medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor's advice. Call your doctor if your symptoms do not improve, or if they get worse. You will need frequent medical tests to check your heart and kidney function. Store at room temperature away from moisture and heat. What happens if I miss a dose? Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause nausea, vomiting, numbness or tingling, dizziness, double vision, confusion, or fainting. What should I avoid while taking ranolazine? Avoid driving or hazardous activity until you know how ranolazine will affect you. Your reactions could be impaired. Grapefruit may interact with ranolazine and lead to unwanted side effects. Avoid the use of grapefruit products. Ranolazine side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: a light-headed feeling, like you might pass out; fast or pounding heartbeats, fluttering in your chest; or kidney problems--little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath. Common side effects may include: nausea, constipation; headache; or dizziness. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Ranolazine dosing information Usual Adult Dose for Angina Pectoris: 500 mg orally twice a day; increase to 1000 mg orally twice a day as needed Maximum dose: 1000 mg orally twice a day Use: Treatment of chronic angina   What other drugs will affect ranolazine? Tell your doctor about all your current medicines. Many drugs can affect ranolazine, especially: any other medicine to treat heart disease; an antibiotic or antifungal medicine; cholesterol-lowering medicine; oral diabetes medicine; medicine to prevent organ transplant rejection; medicine to treat a mental illness; or medicine to treat or prevent nausea and vomiting caused by chemotherapy or radiation. This list is not complete and many other drugs may affect ranolazine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is rasagiline? Rasagiline is used to treat symptoms of Parkinson's disease (stiffness, tremors, spasms, poor muscle control). Rasagiline is sometimes used with another medicine called levodopa. Rasagiline may also be used for purposes not listed in this medication guide. Warnings Tell your doctor about all medicines you have used in the 2-week period before you start taking rasagiline. Many drugs can interact with rasagiline, and some drugs should not be used together. Before taking this medicine You should not take rasagiline if you are allergic to it. Do not use rasagiline if you have used any other MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, selegiline, tranylcypromine, and others. Many drugs can interact and cause dangerous effects. Some drugs should not be used together with rasagiline. Your doctor may change your treatment plan if you also use: cyclobenzaprine (a muscle relaxer); dextromethorphan (contained in many over-the-counter cough medicines); meperidine (Demerol); methadone; St. John's wort; or tramadol (Ultram, Ultracet). Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, migraine headaches, serious infections, or prevention of nausea and vomiting. These medicines may interact with rasagiline and cause a serious condition called serotonin syndrome. Tell your doctor if you have ever had: high or low blood pressure; liver or kidney disease; or if you take ciprofloxacin (an antibiotic). People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Ask your doctor about skin symptoms to watch for. Tell your doctor if you are pregnant or breastfeeding. How should I take rasagiline? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. If you take rasagiline alone, your dose may be different than if you take rasagiline with other Parkinson's medications. Follow your doctor's dosing instructions very carefully. Rasagiline may be only part of a complete program of treatment that also includes a special diet. Follow the diet plan created for you by your doctor or nutrition counselor. Get familiar with the list of foods you should avoid to help prevent certain side effects of rasagiline. Call your doctor if your Parkinson's symptoms do not improve, or if they get worse while using rasagiline. Store at room temperature away from moisture and heat. Do not stop using rasagiline suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using rasagiline. What happens if I miss a dose? Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of rasagiline can be fatal. Overdose symptoms may include drowsiness, dizziness, severe headache, rapid pulse, feeling agitated or irritable, muscle spasms in your neck or jaw, sweating, cold or clammy skin, shallow breathing, fainting, or seizure (convulsions). These symptoms may be delayed for 12 to 24 hours after an overdose. What should I avoid while taking rasagiline? Avoid driving or hazardous activity until you know how rasagiline will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Avoid drinking alcohol, especially red wine, vermouth, and tap beers or ale. Also avoid eating foods that are high in tyramine, such as aged cheeses, fava beans, soy sauce, herring, pickled or processed meats and fish, and meats that are aged, dried, smoked, or fermented. Eating tyramine while you are taking rasagiline can raise your blood pressure to dangerous levels which could cause life-threatening side effects. Rasagiline side effects Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: severe headache, blurred vision, pounding in your neck or ears; extreme drowsiness or falling asleep suddenly, even after feeling alert; unusual changes in mood or behavior; hallucinations; a light-headed feeling, like you might pass out; or worsening symptoms of Parkinson's disease (especially uncontrolled muscle movements). Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Some people taking rasagiline with levodopa have fallen asleep during normal daytime activities such as working, talking, eating, or driving. Tell your doctor if you have any problems with daytime sleepiness or drowsiness. You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs. Common side effects may include: depressed mood; sleep problems (insomnia), strange dreams; involuntary muscle movements; loss of appetite, weight loss; indigestion, stomach pain, nausea, vomiting, constipation; joint pain or stiffness; rash; cough or other flu symptoms; dry mouth; or swelling in your hands or feet. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Rasagiline side effects (more detail) Rasagiline dosing information Usual Adult Dose for Parkinson's Disease: Monotherapy: Recommended dose: 1 mg orally once a day Adjunct therapy: Initial dose (in patients on concomitant levodopa): 0.5 mg orally once a day Initial dose (in patients not on concomitant levodopa): 1 mg orally once a day Maintenance dose: 0.5 mg to 1 mg orally once a day Maximum dose: 1 mg orally once a day Comments: May be used as adjunct therapy in patients on levodopa therapy, with or without other drugs used in the treatment of Parkinson's disease. Detailed Rasagiline dosage information What other drugs will affect rasagiline? Using rasagiline with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor if you have taken an antidepressant during the 2-week period before you start taking rasagiline. Many drugs can affect rasagiline, and some drugs should not be used at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

What is repaglinide? Repaglinide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. repaglinide is not for treating type 1 diabetes. Repaglinide may also be used for purposes not listed in this medication guide. Warnings You should not use repaglinide if you have type 1 diabetes, severe liver disease, or diabetic ketoacidosis. You should not use repaglinide together with gemfibrozil or NPH insulin (such as isophane insulin). Before taking this medicine You should not use repaglinide if you are allergic to it, or if you have: severe liver disease; or diabetic ketoacidosis (call your doctor for treatment). Many drugs can interact with repaglinide and some drugs should not be used at the same time. Your doctor may change your treatment plan if you also use: clopidogrel; cyclosporine; gemfibrozil; or NPH insulin (such as isophane insulin). Tell your doctor if you have ever had: liver disease; or if you also take metformin or other diabetes medicines. Follow your doctor's instructions about using repaglinide if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby. You should not breastfeed while using repaglinide. Repaglinide is not approved for use by anyone younger than 18 years old. How should I take repaglinide? Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Repaglinide is usually taken 2 to 4 times daily, within 30 minutes before eating a meal. Follow your doctor's instructions. If you skip a meal, do not take your dose of repaglinide. Wait until your next meal. Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda). Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency. Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination. Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule. Repaglinide is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely. Store repaglinide at room temperature away from moisture and heat. What happens if I miss a dose? Take your dose as soon as you can, but only if you are getting ready to eat a meal. If you skip a meal, skip the missed dose and wait until your next meal. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A repaglinide overdose can cause life-threatening hypoglycemia. Symptoms of severe hypoglycemia include extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions). What should I avoid while taking repaglinide? Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment. Repaglinide side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Call your doctor at once if you have: pale or yellowed skin, dark colored urine, fever, confusion or weakness; or pancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting. Common side effects may include: low blood sugar; nausea, diarrhea; headache, back pain; joint pain; or cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   Repaglinide dosing information Usual Adult Dose for Diabetes Type 2: Individualize therapy: Dose preprandially 2, 3, or 4 times a day -For patients not previously treated with antidiabetic agents or whose glycosylated hemoglobin (HbA1c) is less than 8%: Initial dose: 0.5 mg orally with each meal -For patients previously treated with antidiabetic agents or whose HbA1c is 8% or higher: Initial dose: 1 or 2 mg orally with each meal Dose Adjustments: Based upon blood glucose response, double the preprandial dose up to a maximum meal time dose of 4 mg until satisfactory glycemic response is achieved; allow at least 1 week to assess response after each dose adjustment. Recommended Dose Range: 0.5 to 4 mg orally with each meal Maximum Daily Dose: 16 mg per day Comments: -Fasting blood glucose concentrations are generally used to adjust doses, however, postprandial glucose levels may be used in patients whose pre-meal blood glucose levels are satisfactory but whose overall glycemic control (HbA1c) is inadequate. -When hypoglycemia occurs in patients taking this drug in combination with a thiazolidinedione or metformin, the dose of this drug should be reduced. Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.   What other drugs will affect repaglinide? Many other medicines that can increase or decrease the effects of repaglinide on lowering your blood sugar. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What is risedronate? Risedronate is used to treat osteoporosis caused by menopause, or steroid use. risedronate is for use when you have a high risk of bone fracture due to osteoporosis. Risedronate is also used to treat Paget's disease of bone. Risedronate may also be used for purposes not listed in this medication guide. Warnings You should not take risedronate if you have problems with your esophagus, or low levels of calcium in your blood. Do not take risedronate if you cannot sit upright or stand for at least 30 minutes after taking the medicine. Risedronate can cause serious problems in the stomach or esophagus. Stop using risedronate and call your doctor at once if you have chest pain, new or worsening heartburn, or pain when swallowing. Also call your doctor if you have muscle spasms, numbness or tingling (in hands and feet or around the mouth), new or unusual hip pain, or severe pain in your joints, bones, or muscles. Before taking this medicine You should not take risedronate if you are allergic to it, or if you have: low levels of calcium in your blood (hypocalcemia); or problems with the muscles in your esophagus (the tube that connects your mouth and stomach). Do not take risedronate if you cannot sit upright or stand for at least 30 minutes. Risedronate can cause serious problems in the stomach or esophagus. You must stay upright for at least 30 minutes after taking risedronate. Tell your doctor if you have ever had: trouble swallowing; problems with your stomach or digestion; hypocalcemia; a dental problem (you may need a dental exam before you begin taking risedronate); kidney disease; or any condition that makes it hard for your body to absorb nutrients from food (malabsorption). This medicine may cause jaw bone problems (osteonecrosis). The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. Ask your doctor about your own risk. Talk with your doctor about the risks and benefits of using this medication. It is not known whether this medicine will harm an unborn baby. Stop taking risedronate and tell your doctor right away if you become pregnant, or think you may be pregnant. You should not breastfeed while using risedronate. Risedronate should not be given to a child younger than 18 years old. How should I take risedronate? Risedronate tablets come in different strengths (number of milligrams per pill) that are taken on different schedules. You may need to take a tablet once per day, once per week, once per month, or for 2 days in a row once per month. Your dosing schedule will depend on why you are taking risedronate and in what tablet strength. If you change strengths, you may also need to change your schedule. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Risedronate is often given for only 3 to 5 years. Take the Actonel tablet first thing in the morning with a full glass (6 to 8 ounces) of water, at least 30 minutes before you eat or drink anything or take any other medicine. Take the Atelvia tablet just after breakfast, with at least 4 ounces of water. Use only plain water when taking a risedronate tablet. Do not use coffee, tea, soda, juice, or mineral water. Do not crush, chew, or suck on a risedronate tablet. Swallow it whole. For at least 30 minutes after taking risedronate: Do not lie down or recline. Do not take any other medicine including vitamins, calcium, iron, antacids, or laxatives. Take this medicine at the same time each day or on the same day each week or each month (depending on your dosing schedule). Pay special attention to your dental hygiene while taking risedronate. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using risedronate. Risedronate is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely. Store at room temperature away from moisture and heat. Keep unused effervescent tablets in the foil blister pack.   What happens if I miss a dose? Once-daily dosing: If you forget to take risedronate first thing in the morning, do not take it later in the day. Wait until the following morning and skip the missed dose. Do not take two (2) doses in one day. Once-per-week or once-per-month dosing: If you forget to take risedronate on your scheduled day, take it first thing in the morning on the day after you remember the missed dose. Then return to your regular weekly or monthly schedule on your chosen dose day. Do not take 2 doses in one day. Call your doctor for instructions if you miss more than 2 doses in a month. What happens if I overdose? Drink a full glass of milk and seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not make yourself vomit and do not lie down. What should I avoid while taking risedronate? Do not take two different brands or strengths of risedronate at the same time. Avoid taking any other medicines for at least 30 minutes after taking risedronate. This includes vitamins, calcium, iron, antacids, or laxatives. Some medicines can make it harder for your body to absorb risedronate. Avoid smoking, or try to quit. Smoking can reduce your bone mineral density, making fractures more likely. Avoid drinking large amounts of alcohol. Heavy drinking can also cause bone loss. Risedronate side effects Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling). Stop using risedronate and call your doctor at once if you have: chest pain, new or worsening heartburn; difficulty or pain when swallowing; pain or burning under the ribs or in the back; severe heartburn, burning pain in your upper stomach, or coughing up blood; new or unusual pain in your thigh or hip; jaw pain, numbness, or swelling; severe joint, bone, or muscle pain; or low calcium levels--muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes). Common side effects may include: heartburn, diarrhea, indigestion; stomach pain; back pain, joint pain, muscle pain; or flu-like symptoms. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect risedronate? Tell your doctor about all your other medicines, especially: aspirin; calcium or iron supplements; antacids, laxatives; or NSAIDs (nonsteroidal anti-inflammatory drugs)--ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others. This list is not complete. Other drugs may affect risedronate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What is risperidone? Risperidone is an antipsychotic medicine that works by changing the effects of chemicals in the brain. Risperidone is used to treat schizophrenia in adults and children who are at least 13 years old. Risperidone is also used to treat symptoms of bipolar disorder (manic depression) in adults and children who are at least 10 years old. Risperidone is also used to treat symptoms of irritability in autistic children who are 5 to 16 years old. Warnings Risperidone is not approved for use in older adults with dementia-related psychosis. Do not give risperidone to a child without a doctor's advice. While you are taking this medicine, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medication. Risperidone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of this medicine. Stop using this medicine and call your doctor at once if you have fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, restless muscle movements in your face or neck, tremor (uncontrolled shaking), trouble swallowing, feeling light-headed, or fainting. Before taking this medicine You should not use risperidone if you are allergic to it. Risperidone may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. To make sure this medicine is safe for you, tell your doctor if you have ever had: heart disease, high blood pressure, heart rhythm problems, stroke or heart attack; diabetes (or risk factors such as obesity or family history of diabetes); low white blood cell (WBC) counts; liver or kidney disease; seizures; breast cancer; low bone mineral density; trouble swallowing; Parkinson's disease; or if you are dehydrated. The risperidone orally disintegrating tablet may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU). Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking risperidone, do not stop taking it without your doctor's advice. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of risperidone on the baby. This medicine may temporarily affect fertility (ability to have children) in women. Risperidone can pass into breast milk and may cause side effects in the baby. If you breast-feed while using this medicine, tell your doctor if the baby has symptoms such as drowsiness, tremors, or involuntary muscle movements. Do not give this medicine to a child without a doctor's advice. How should I take risperidone? Take risperidone exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Risperidone can be taken with or without food. Remove an orally disintegrating tablet from the package only when you are ready to take the medicine. Place the tablet in your mouth and allow it to dissolve, without chewing. Swallow several times as the tablet dissolves. Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). Do not mix the liquid medicine with cola or tea. It may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve. Store at room temperature away from moisture, heat, and light. Do not liquid medicine to freeze.   What happens if I miss a dose? Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe drowsiness, fast heart rate, feeling light-headed, fainting, and restless muscle movements in your eyes, tongue, jaw, or neck. What to avoid Avoid driving or hazardous activity until you know how risperidone will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Dizziness or severe drowsiness can cause falls, fractures, or other injuries. Avoid drinking alcohol. Dangerous side effects could occur. While you are taking risperidone, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. Risperidone side effects Get emergency medical help if you have signs of an allergic reaction to risperidone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); breast swelling or tenderness (in men or women), nipple discharge, impotence, lack of interest in sex, missed menstrual periods; severe nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out; low white blood cells - sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing, skin sores, cold or flu symptoms, cough, trouble breathing; low levels of platelets in your blood - easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin; high blood sugar - increased thirst, increased urination, dry mouth, fruity breath odor; or penis erection that is painful or lasts 4 hours or longer. Common risperidone side effects may include: headache; dizziness, drowsiness, feeling tired; tremors, twitching or uncontrollable muscle movements; agitation, anxiety, restless feeling; depressed mood; dry mouth, upset stomach, diarrhea, constipation; weight gain; or cold symptoms such as stuffy nose, sneezing, sore throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.   What other drugs will affect risperidone? Taking risperidone with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: blood pressure medication; carbamazepine; clozapine; fluoxetine (Prozac) or paroxetine (Paxil); or levodopa. This list is not complete. Other drugs may interact with risperidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.