Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days Methodology Immunoassay - Analyte Specific Reagents Assay Category This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes. Alternative Name(s) ImmunoCAP®

Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

Clinical Significance Goose Feathers (e70) IgE - This test is an allergen-specific IgE antibody test that quantifies an individual’s IgE response to goose feathers. It is an in vitro quantitative assay, which is intended to be used in conjunction with other clinical information to aid in the diagnosis of allergic diseases [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. A definitive clinical diagnosis of allergy should not be based on the results of any single diagnostic method, but should be made by a trained healthcare professional after all clinical and laboratory findings have been evaluated. Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

"Preferred Specimen(s) 1.5 mL serum Minimum Volume 0.15 mL/allergen Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days Includes Orchard Grass (Cocksfoot) (g3) Perennial Rye Grass (g5) Timothy Grass (g6) Red Top Grass (g9) Johnson Grass (g10) Methodology Immunoassay (IA) Reference Range(s) See Laboratory Report Alternative Name(s) ImmunoCAP®

Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days Methodology Immunoassay - Analyte Specific Reagents Assay Category This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes. Alternative Name(s) ImmunoCAP®

Clinical Significance Guar Bean Gum (f246) IgE - This test is an allergen-specific IgE antibody test that quantifies an individual’s IgE response to guar gum. It is an in vitro quantitative assay, which is intended to be used in conjunction with other clinical information to aid in the diagnosis of food allergy [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. Food-specific IgE tests are extremely sensitive. However, a positive test result only indicates that a patient is IgE sensitized to the food of concern. Many IgE-sensitized patients do not develop any symptoms when this food is ingested. A diagnosis of food allergy should only be made by a trained medical provider, after conducting a thorough clinical evaluation [2,3]. While food-specific IgE test results may contribute to that evaluation, they cannot replace it. In this regard, detection of food-specific IgE in serum provides evidence of IgE sensitization, but a history of clinical reactivity to the food of concern, is required to make a diagnosis of IgE-mediated food allergy. Moreover, several forms of food hypersensitivity are not associated with the presence of food-specific IgE in serum. Preferred Specimen(s) 0.3 mL serum Minimum Volume 0.15 mL/allergen Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days Methodology Immunoassay (IA) Assay Category This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes. Alternative Name(s) ImmunoCAP®

Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

"Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

What are the other names for this test? H.pylori breath tests, urea breath test, CLO test, H.pylori stool antigen, Rapid urease test (RUT) for H.pylori What is the H.Pylori antigen stool test? This test helps to diagnose helicobacter pylori infection in your digestive system through the stool sample. H.pylori infection develops when helicobacter pylori bacteria enter your stomach. H.pylori bacteria spread from person to person via physical contact with saliva, stool, or vomit. It may also transmit through polluted water or food. This infection is one of the leading causes of stomach ulcers (peptic ulcers). Peptic ulcers are sores that may develop on the lining of the stomach, small intestine, or esophagus (the muscular tube that transfers food and liquids from your mouth to the stomach). H.pylori infections are common because about half of the world’s population has experienced it. H.pylori does not show symptoms in most people. This infection may lead to ulcers (peptic ulcer disease), consistent stomach inflammation (gastritis), and gastric (stomach) cancer. The H.pylori bacteria reduces the function of the stomach to develop mucus that allows stomach damage from digestive acid and peptic ulcers. What is the purpose of the Helicobacter pylori antigen stool test? This test detects the H.pylori antigen in your stool sample. A healthcare provider uses a stool antigen test or urea breath test to look for H.pylori infection and monitor the effectiveness of treatment. Both these tests are mostly used because they provide fast results. A doctor usually recommends a H.pylori antigen stool test to children instead of a urea breath test. Why do I need an H.pylori stool test? H.pylori infection does not indicate any signs to most people. The reason is still not clear. If you have signs and symptoms develop along with H.pylori infection, they are linked with a peptic ulcer or gastritis. Symptoms of peptic ulcer include:   Burning pain or inflammation in the stomach Stomach pain that goes worse if you have an empty stomach Reduction in hunger Nausea and vomiting Increased burping (Excretion of excess air from your upper digestive tract) Bloating Unexpected weight loss You may need the H.pylori antigen stool test if you experience these symptoms of peptic ulcer. A provider may order this test if you have the following serious medical condition, such as:   Extreme pain in the stomach that can urge to wake up from sleep Blood or black tarry in the stools Blood in the vomiting seems to be coffee grounds. A healthcare provider may also order this test within 4 to 6 weeks when you have received the treatment from medication to check that the infection is eliminated. What are the risk factors for developing H.pylori infection? Most H.pylori infections develop in the beginning or middle of childhood. Following are the risk factors that may lead to H.pylori infection, including:   A resident of the crowded place Receiving an unclean water supply Living in a developing country Living with people who already infected with an H.pylori infection What happens during the H.pylori antigen stool test? This test collects the stool sample to find the H.pylori infection. The stool antigen test checks for proteins (antigens) linked with H.pylori in the stool. Antigens are the substances that activate the response of your immune system. Following are the steps that are generally involved in collecting the stool sample:   You need to wear rubber gloves during the collection of the stool sample. A healthcare provider will provide a specimen sample to collect the stool sample. If you are a parent and want to collect a stool sample from your child or baby, cover the baby’s diaper with plastic wrap. Avoid mixing urine, water, or toilet paper within the specimen sample. Tight the container Wear Off your gloves and wash your hands. Provide the specimen sample to your healthcare provider. How do I need to prepare for this test? No special preparation is required for this test. Inform your provider if you are using particular medicines for a long time. Your provider may ask you to stop these medicines. What are the risks involved in this test? No risks are involved in the stool antigen test. What does the H.pylori antigen stool test result indicate? A positive H.pylori antigen stool test shows that you have the signs and symptoms of peptic ulcer developed by H.pylori bacteria. A healthcare provider may recommend a group of antibiotics or medicines to eliminate the bacteria and reduce ulcer pain. A negative test result tells that you may not have an H.pylori infection. If you have signs and symptoms, it may develop because of other reasons. You may need additional testing, such as a biopsy, to eliminate the infection if the symptoms remain present. You can consult an online provider to understand your test result and receive treatment for H.pylori. What other tests do I need to take along with this test? A provider may ask for other samples with the stool test for H.pylori infection, which is as under:   Blood test. This test is used to see antibodies in response to H.pylori infection. Breath test. This test is also known as the urea breath test. A urea breath test helps to observe infection by evaluating the specific substances in your breath. Stool Culture. This test checks for H.pylori bacteria in the stool. Endoscopy. This procedure helps your provider see your esophagus (a tube connected from your mouth to the stomach), stomach lining, and small intestine.

Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

Preferred Specimen(s) 0.3 mL serum Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

Preferred Specimen(s) 0.3 mL serum Minimum Volume 0.15 mL/allergen Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

Preferred Specimen(s) 0.3 mL serum Minimum Volume 0.15 mL/allergen Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

"Preferred Specimen(s) 1.5 mL serum Minimum Volume 1 mL Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days Includes If Hazelnut (f17) IgE is ≥0.10 kU/L, Hazelnut Component Panel will be performed at an additional charge (CPT code(s): 86008 x4). Hazelnut Component Panel includes Cor a1 (f428), Cor a8 (f425), Cor a9 (f440), and Cor a14 (f439). Methodology Immunoassay (IA) Assay Category Reference Range(s) See Laboratory Report Alternative Name(s) ImmunoCAP®

HCG lab test Other names for HCG The test for chorionic gonadotropin is also known as the Total Quantitative Test, Human Chorionic Gonadotropin, Human Chorionic Gonadotropin Quantitative Total, and Test for Pregnancy.   What is human chorionic gonadotropin (HCG)?  Human chorionic gonadotropin (HCG) is a type of hormone the body produces in large amount during pregnancy.   What is the HCG lab test? A quantitative human chorionic gonadotropin (HCG) test determines the number of HCG hormones present in the blood. This test makes it easier to analyze whether you are pregnant or not and helps find out about abnormal pregnancies. Symptoms of abnormal pregnancies   unexpected vaginal bleeding discomfort in the abdomen Feeling dizzy or faint shoulders hurt Vomiting Weakness/dizziness reduced blood pressure flue/fever   Why do I need this test? The doctor may want you to have this test to check if you are pregnant. You are also asked to have this test if you have vaginal bleeding or cramping. This could also mean you have an irregular pregnancy. The doctor would also want to know about your pregnancy progress and might order this test more than once after a few days.   What is the HCG process during pregnancy? Approximately 10–11 days after conception, hCG can be seen in a blood sample. After every 48–72 hours, the levels begin to double. Around 8 to 11 weeks after conception, they reach their peak. Following a decline and plateau, hormone levels remain constant for the duration of the pregnancy. Why is this test performed? HCG develops in the blood and urine of pregnant women almost 11 days after conception. This test helps to determine the approximate age of the fetus (unborn baby). It helps to learn about irregular pregnancies such as molar pregnancies, ectopic pregnancies, and miscarriages and is also used for screening for Down syndrome.   How is this test performed?   This test can be carried out in one of two ways: BLOOD TEST: A sample of blood is required for this test. Blood is collected with a small needle and placed in a test container. Your healthcare provider will instruct you to press a bandage that is wrapped around your vein. The test only lasts five minutes. Book an online test at UmbrellaMD now. URINE TEST: Urine tests can also be done at home. It will inform you if it finds the hormone in your urine or not. It's not meant to give out the hormone's exact concentrations. A positive indicator of pregnancy is the presence of hCG in your urine   How do I prepare for the test? For this test, there is no need for preparation. To be safe, make sure that all of the medications, vitamins, and supplements you use are known to your healthcare provide, or anything that you think the healthcare should know about you tell them about it.  What will happen during the test? You might feel a pinch of pain when the needle is injected into the vein. Some people feel a prickling or stinging sensation. The level of pain varies from person to person. There may be some wavering afterward.   Is there any risk associated with it? Having a blood test comes with some risks.   a tiny bruise where the needle was inserted a lot of blood infection (at the needle site) Fainting/lightheadedness Hematoma (blood accumulating under the skin)   Is there any other reason besides pregnancy for this test Beta-HCG is a hormone that causes tumors and is thus classified as a tumor promoter. Due to this reason, the HCG blood test is often used to identify and treat certain cancer forms.   Are there any further tests needed besides this one? Your doctor may additionally request an ultrasound if you are pregnant to check for specific issues. Estradiol and progesterone, two more hormones, could also be examined in your blood. Estradiol, an estrogen subtype, can be measured to determine how well the pregnancy is functioning. Progesterone levels rise throughout pregnancy, and they can help your doctor determine whether you are at risk for pregnancy loss or miscarriage.   What are normal HCG results? Normal levels are for non-pregnant women. During pregnancy, in the first stage, HCG levels rise quickly before beginning to slowly decline over time. The expected HCG range in pregnant women is based on the extent of pregnancy. 5 to 72 mIU/mL after 3 weeks. 10-708 mIU/mL over a 4-week period. During 5 weeks, the concentration ranged from 217-8,245 mIU/mL. After six weeks, the level ranged from 152 to 32,177 mIU/mL. 4,059-153,767 mIU/mL over a 7-week period 31,366 to 149,094 mIU/mL over 8 weeks 59,109 to 135,901 mIU/mL over 9 weeks 44,186–170,409 mIU/mL over 10 weeks 27,107–201,165 mIU/mL after 12 weeks. 14 weeks: 14,302-93,646 mIU/mL 12,540-669,747 mIU/mL at 15 weeks 8,904-555,332 mIU/mL at 16 weeks The range of normal values varies slightly among different laboratories.   What are abnormal HCG results? Results higher than the normal range state A twin or triple pregnancy A molar pregnancy Ovarian cancer Testicular cancer (in men) Results below the normal range could mean An ectopic pregnancy A miscarriage Fetal death If you do not have a prescription, go to Umbrella Health Care Systems to place an order for this lab test. Umbrella Health Care Systems is a healthcare site that offers online services such as e-consultation, medical imaging, primary care, lab testing, and pharmacies. Your test results can all be analyzed and explained while you’re at home. To find out more about this healthcare platform, register here.

HDL CHOLESTEROL TEST What are the other names for this test? HDL Test, High-density lipoprotein cholesterol test, HDL-C test, Good Cholesterol test, High-density lipoprotein test What is an HDL Cholesterol test? An HDL cholesterol test helps to observe HDL levels in your blood. HDL (High-density Lipoprotein) is a type of lipoprotein present in your body. HDL consists of a combination of lipids and fats. Lipids combine with proteins for their flow into the blood. Low HDL levels may indicate health problems such as heart disease. Cholesterol is a waxy substance like fat present in all your body cells. Your liver develops cholesterol in your body. You get cholesterol from foods like meat and dairy products. Some healthy cholesterol is needed for different body functions. HDL is good cholesterol, which helps to move cholesterol from parts of your body to your liver. Your liver helps to eliminate cholesterol from your body. HDL cholesterol provides maintenance of the inner walls of the blood vessel. Atherosclerosis is a condition that narrows your arteries developed by the deposition of cholesterol in your arteries. It leads to heart attacks and strokes. HDL cholesterol helps to clean the inner walls and make them healthy. What is the purpose of this test? An HDL cholesterol test diagnoses cardiovascular health problems such as developing a risk for heart disease. HDL-C test also helps screen and monitor specific problems that may affect your heart, blood vessels, and blood supply to your body. HDL cholesterol test is often conducted with total cholesterol test, and these two are included in lipid panel test. When do I need to take this test? A healthcare provider recommends the HDL cholesterol test to every age group. The following are the considerations for this test: People aged 19 or below   The initial test should be conducted at ages starting from 9 to 11. Children need to take this test every five years. Some children may need this test at age two if they have a family history of high blood cholesterol, heart attack, or stroke. People aged 20 or above   You should take this test every five years if you are a young adult. Men and women ages 45 to 65 and 55 to 65, respectively, should take this test every one to two years. Your provider may also suggest this test by observing your age, risk factors, and family history. You can take an HDL cholesterol test at a discounted price. What is the procedure for this test? An HDL cholesterol test often performs with a blood sample. A healthcare provider may collect blood samples from your vein. The following are the steps for collecting blood samples from your vein after visiting the laboratory.   Sit in front of your provider. Be relaxed and stay in a fixed position. It is difficult for your provider to collect a blood sample if you do the muscle movement. Remove the portion of your cloth from the arm and elastic band tie on your upper arm. A small needle will inject into a vein in your arm. A small amount of blood will collect in a test tube. Blood samples will store in the laboratory for examination of an allergy. You can go home for regular activities. This test usually takes five minutes. How do I need to prepare for this test? An HDL Cholesterol test does not require special preparation. You can inform your provider about the medicines or supplements you are using. Your provider will instruct you when to stop or take your medications. You can eat or drink before the test. You may need to fast for several hours if your provider asks for an additional blood test. Are there any risks involved in this test? An HDL Cholesterol test does not have high risks when you give a blood sample. Veins differ from person to person. Some people or children may have difficulty providing a blood sample compared to others. You may experience low risks when the needle injects into your vein. These risks include   Bruising Extreme Bleeding Slight pain Infection Hematoma (Deposition of blood under the skin) What do the test results indicate? HDL cholesterol test results depend on many factors, such as age, gender, and medical history. The test results may also slightly differ among laboratories. It is because each lab may use different methods for examination. High HDL cholesterol levels may decrease your chance of heart stroke and coronary artery disease. The measurement unit of HDL cholesterol is a milligram per deciliter (mg/dL). The recommended range of healthy HDL cholesterol levels are:   Above 45 mg/dL to age 19 or younger Above 40 mg/dL to men aged 20 or above Above 50 mg/dL to women aged 20 or above Low HDL levels may develop due to the following conditions:   Being overweight Poor diet Smoking Lack of physical exercise High blood glucose levels Few cholesterol medicines may increase HDL levels, such as statins if you use them to decrease your LDL level. You do not require any medication or supplement to increase HDL levels. You may need medication if you experience low HDL and high LDL levels. How can I increase my HDL cholesterol levels? You may increase your HDL levels by applying these steps in your daily lifestyle, including:   Taking a healthy diet - You can eat healthy saturated fats rather than bad trans fats. The saturated fats include cheese, high-fat meats, full-fat milk, and things made from butter. You can avoid trans fats such as fried and processed foods. Maintain a healthy weight - Reduce your weight if you have a high deposition of fats in your belly and waist. Do physical activity daily - At least 30 minutes of exercise each day will increase your HDL levels and decrease your LDL levels. Decrease your alcohol consumption - You can avoid the use of alcohol to increase your HDL levels. Quit smoking - Avoiding smoking will boost your HDL levels. You can get more ways to increase your HDL cholesterol levels by e-consultation with a provider. What factors may affect the test results? Diabetes may also decrease your HDL levels. Some medicines may reduce HDL levels in a few people, including:   Progestin - Females hormones present in birth control pills and hormone replacement therapy Benzodiazepines - It is used to eliminate insomnia and stress. Beta-blockers - A blood pressure medicine Anabolic steroids present in testosterone (a male hormone) You can ask your provider about the continuation of these medications if you are using any of these and experiencing low HDL levels. What additional tests do I need along with this test? Your healthcare provider may recommend the following test along with the HDL cholesterol test: Total Cholesterol test: This test determines HDL and LDL amounts in the blood. LDL Cholesterol test:  This test helps to measure LDL (bad cholesterol) levels in your blood.

HELICOBACTER PYLORI BREATH Test, UREA BREATH TEST, H.PYLORI What are the other names for this test? H.Pylori, Helicobacter pylori, H.pylori breath test What is a Urea Breath Test? A urea breath test helps look at your breath for Helicobacter pylori (H.pylori), a common infection. The H.pylori breath test is a simple method to identify H.pylori bacteria and infection. H.pylori is a general bacteria that cause damage to your stomach or duodenum (the first part of the small intestines). H.pylori bacteria often develop in childhood and can remain in the stomach for a long time if not get treatment. A big reason for H.pylori infection is due to peptic ulcer disease. A peptic ulcer in the stomach is known as a gastric ulcer. It is a form of sores that develops on the lining of your stomach and small intestine. This lining of the stomach helps to prevent the stomach from the strong stomach acid, which digests food. The signs and symptoms of H.pylori infection do not appear as it mostly lives in your stomach lining. In some people, the H.pylori infection leads to stomach cancer and gastritis (inflamed lining of your stomach). What is the purpose of the H.pylori breath test? An H.pylori breath test determines the presence of H.pylori bacteria in your stomach. An H.pylori bacteria lives in your stomach and produces an enzyme called urease that forms urea. Urease helps to convert urea into ammonia and carbon dioxide. A urea breath test measures the traces of carbon dioxide in your breath to find the presence of H.pylori bacteria in your stomach. This test may also suggest for adults and children aged above six years if they can coordinate with the test. An H.pylori breath test helps your doctor to:   Diagnose the ulcer in your stomach or upper small intestine. Observe an ulcer if you have experienced it in the past and didn’t take this test before. Monitors the effectiveness of the treatment if a person has experienced H.pylori infection. When to conduct this test? Your healthcare provider may recommend the H.pylori breath test if you are giving treatment for an H.pylori infection. In general, about 50 % of people had infected with H.pylori bacteria throughout the world. Symptoms of the bacteria do not show up in most people. An H.pylori infection leads to problems in the stomach. Therefore, if you experience any pain in your digestive system, you may need to take this test. You may also place an online order for a urea breath test if you see symptoms of peptic ulcer (a form of sores that develops on the lining of your stomach and small intestine). The following are the symptoms of peptic ulcer that include:   Bloating Feeling pain when you eat something or use an antacid. A condition of burning in your middle or upper stomach during meals or at night. Nausea and vomiting Weight Loss Burning or inflammation in the heart. What is the procedure for the H.pylori breath test? In a urea breath test, your provider will first discuss the procedure with you, which may take about 40 to 60 minutes. You will guide about the following steps to take your breath sample.   You will first exhale into a balloon-like bag to measure your first sample for carbon dioxide. For a second sample, you will need to chew up a tablet or capsule containing urea. After 15 to 20 minutes, you will again need to exhale that tablet into a bag similar to a balloon. The amount of carbon dioxide will measure with an instrument or device for a second time. The carbon dioxide will release when you take a breath in a bag because your body can absorb it. Your breath samples will go to the laboratory for examination. You can go home for regular activities. You can take your regular diet or medicines if you take them. How do I get ready for this test? You have to follow these steps for the urea breath test:   Avoid eating or drinking at least 4 to 6 hours before your test. Stop the use of antibiotics at least four weeks before the test. If you are pregnant, have heart or lung problems, or any other disease, talk with your provider. Inform your doctor if you have an allergy to any medications. Avoid the intake of gum on the day of your test. With approval from your doctor, you can take medicine on the day of the test. Do not use the following medications at least 2 to 4 weeks before your test. Proton pump inhibitors (Aciphex, Nexium, Prevacid, Prilosec, etc.) Bismuth subsalicylate Histamine blockers          What are the risks of the H.pylori breath test? This test does not have any risk. What do the test results indicate? The urea breath test results depend on age, gender, medical history, and other factors. An H.pylori breath test can measure H.pylori bacteria by noticing the difference between the first and second samples of carbon dioxide levels. If you want to get more information about your test results with more details, you can book an online talk with a doctor. The positive test results indicate higher carbon dioxide levels in your second sample compared to the first sample. It shows that an H.pylori infection lies in your stomach. The negative test results show no difference between the first and second samples of your carbon dioxide. It indicates that there is no H.pylori infection in your stomach. What are the factors that may change the H.pylori breath test results? You may receive an inaccurate or false-negative result if you perform this test earlier after treatment. It shows that H.pylori bacteria are present in your stomach, but in reality, they are not. The use of specific medications may also affect the test results. You may need to repeat this test at least four weeks after treatment for H.pylori bacteria to receive accurate results. What additional tests do I need to take along with the urea breath test? You may also need the following additional tests with the H.pylori breath test. ● Blood tests ● Stool sample ● Endoscopy - A test in which a thin and lighted tube injects into your stomach by your mouth. This test looks at the lining of your stomach and collects small samples for examination. Umbrella Health Care Systems is an online source of getting knowledge about laboratory tests and e-consultation services. You can register here to solve all your health problems.  

Clinical Significance Alternative Names UBiT, Urea Breath Test, Breath Test, H.pylori Helicobacter pylori, Urea Breath Test, Pediatric - Helicobacter pylori is a gram-negative microaerophilic curved bacillus with an affinity for human gastric mucosa. H. pylori has been identified as an important pathogen in the upper GI tract. The casual relationship between H. pylori and chronic active gastritis, duodenal ulcers, and gastric ulcers has been well documented. BreathTek™ UBiT® for H. pylori is a non-invasive, non radioactive method for detecting urease activity associated with H. pylori infection. This test offers 95.2% sensitivity and 89.7% specificity compared with endoscopic methods. Patient Preparation Patient should fast one hour before collection of baseline breath sample. Pranactin®-Citric contains a small amount of aspartame sweetener. Test may not be suitable for patients with phenylketonuria whose dietary phenylalanine should be restricted. Use of antimicrobials, proton pump inhibitors, or bismuth preparations within two weeks prior to administering the BreathTek™ UBT may cause a false negative result. However, a positive result is still valid. Methodology Infra-red Spectrophotometry (IR) Preferred Specimen(s) Human breath from patients 3-17 years of age: Paired breath samples (pre and post) collected in BreathTek™ UBT Collection Kit bags and must be submitted together. Follow instructions provided with kit. Collection Instructions This test can only be performed on specimens from patients 3-17 years old. Patients >17 years of age must use test code 14839-Helicobacter pylori, Urea Breath Test. Gender, height, weight and age must be provided on the pediatric UHR card included in the BreathTek™ UBT collection kit bags. Place the completed card inside the sample transport bag along with the collected breath samples. Transport Container Tightly capped blue and pink bags. Bags may leak if cap is not attached. Keep each pair of breath samples together reusing the plastic kit pouch provided. Transport Temperature Room temperature Specimen Stability Room temperature: 7 days Refrigerated: Unacceptable Frozen: Unacceptable Reject Criteria Specimen types other than BreathTek™ UBT bags • Specimens from patients <3 years old

Clinical Significance Helminthosporium halodes (m8) IgE - This allergen-specific IgE antibody test quantifies an individual’s IgE response to Helminthosporium halodes. It is an in vitro quantitative assay that is intended to be used in conjunction with other clinical information to aid in the diagnosis of allergic diseases [1]. While allergen-specific serum IgE testing is considered comparable to skin testing in many instances, both the American Academy of Allergy, Asthma, and Immunology and the American College of Allergy, Asthma, and Immunology recognize that allergen-specific serum IgE testing may be preferred in some clinical situations. These include 1) the presence of widespread skin disease, 2) the recent use of antihistamines or other medications that can affect the results of allergy skin tests, 3) uncooperative patients, and 4) medical history suggesting that allergen skin testing would pose a significant risk for a serious allergic reaction [1]. A definitive clinical diagnosis of allergy should not be based on the results of any single diagnostic method, but should be made by a trained healthcare provider after all clinical and laboratory findings have been evaluated. Preferred Specimen(s) 0.3 mL serum Minimum Volume 0.15 mL/allergen Transport Container Serum Separator Tube (SST®) Transport Temperature Room temperature Specimen Stability Room temperature: 14 days Refrigerated: 14 days Frozen: 30 days

"Clinical Significance Hematocrit - Usual method for determining anemia. Used to calculate indices. Preferred Specimen(s) Whole blood from a full EDTA (lavender-top) tube Minimum Volume Microtainer: 0.5 mL • EDTA (lavender-top) tube: 1 mL Collection Instructions Maintain specimen at room temperature. Do not refrigerate. If multiple draw, collect EDTA (lavender-top) tube last. Traumatic draw can introduce thromboplastin and trap WBC and platelets. Refrigeration can precipitate fibrin and trap WBC and platelets. Transport Container EDTA (lavender-top) tube Transport Temperature Room temperature Specimen Stability Room temperature: 48 hours Refrigerated: 48 hours (may cause platelet clumping) Frozen: Unstable Reject Criteria Hemolysis • Clotted • Received frozen Methodology Electronic Cell, Sizing/Cytometry/Microscopy Reference Range(s) ≤2  Weeks    42.0-65.0 % 1 Month    33.0-55.0 % 2 Months    28.0-42.0 % 6 Months    29.0-41.0 % 2 Years    31.0-41.0 % 6 Years    34.0-42.0 % 12 Years    35.0-45.0 %      Male    Female 18 Years    36.0-49.0 %    34.0-46.0 % >18 Years    38.5-50.0 %    35.0-45.0 % Alternative Name(s) HCT